Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006726390                                                           18    1135
XP_006726389                                                           18    1135
XP_006726388                                                           18    1135
XP_006726387                                                           18    1135
XP_006711142                                                           18    1135
XP_006711141                                                           18    1135
XP_006711140                                                           18    1135
XP_006710131                                                           18    1135
XP_006710130                                                           18    1135
XP_006710129                                                           18    1135
XP_006710128                                                           18    1135
NP_149162                                                              17    3301
NP_001835                                                              17    3301
XP_006719305                                                           17    3301
XP_006712967                                                           17    4312
NP_004632                                                              16    5631
NP_001182555                                                           16    5631
NP_001171619                                                           16    5631
NP_005928                                                              16    5631
XP_006725391                                                           16    5631
XP_006725389                                                           16    5631
XP_006725388                                                           16    5631
XP_006725387                                                           16    5631
XP_005257438                                                           16    5631
XP_006721974                                                           16    5631
XP_006721973                                                           16    5631
XP_005257436                                                           16    5631
XP_005252669                                                           16    5631
XP_006717572                                                           16    5631
XP_005252667                                                           16    5631
XP_005252666                                                           16    5631
XP_005252665                                                           16    5631
XP_005252663                                                           16    5631
XP_005252662                                                           16    5631
XP_005262946                                                           16    5631
XP_005262945                                                           16    5631
NP_001120965                                                           16    7355
NP_066187                                                              16    7355
NP_001139                                                              16    7355
NP_055897                                                              16    7355
XP_006714257                                                           16    7355
XP_006714256                                                           16    7355
XP_006714255                                                           16    7355
XP_005263005                                                           16    7355
XP_006714254                                                           16    7355
XP_006714253                                                           16    7355
XP_005263002                                                           16    7355
XP_005262999                                                           16    7355
XP_006714252                                                           16    7355
XP_006714251                                                           16    7355
XP_006714250                                                           16    7355
NP_001186170                                                           15    9605
NP_001153399                                                           15    9605
NP_996985                                                              15    9605
NP_001153401                                                           15    9605
NP_003928                                                              15    9605
NP_659407                                                              15    9605
XP_006724591                                                           15    9605
XP_006724590                                                           15    9605
XP_006724589                                                           15    9605
XP_005272646                                                           15    9605
NP_001028170                                                           15    9605
>XP_006726390
          Length = 1353

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006726389
          Length = 1471

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006726388
          Length = 1489

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006726387
          Length = 1497

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006711142
          Length = 1471

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006711141
          Length = 1489

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006711140
          Length = 1497

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006710131
          Length = 1353

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006710130
          Length = 1471

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006710129
          Length = 1489

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>XP_006710128
          Length = 1497

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AARLRCQ 9
           AARLRCQ
Sbjct: 251 AARLRCQ 257
>NP_149162
          Length = 1418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  VAARLRCQ 9
          VAA LRCQ
Sbjct: 17 VAAVLRCQ 24
>NP_001835
          Length = 1487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  VAARLRCQ 9
          VAA LRCQ
Sbjct: 17 VAAVLRCQ 24
>XP_006719305
          Length = 1488

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  VAARLRCQ 9
          VAA LRCQ
Sbjct: 17 VAAVLRCQ 24
>XP_006712967
          Length = 298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  AARLRC 8
          AARLRC
Sbjct: 29 AARLRC 34
>NP_004632
          Length = 1027

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>NP_001182555
          Length = 1068

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>NP_001171619
          Length = 582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ARLRCQ 9
          AR+RCQ
Sbjct: 67 ARIRCQ 72
>NP_005928
          Length = 1093

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006725391
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006725389
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006725388
          Length = 1094

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006725387
          Length = 1120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_005257438
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006721974
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_006721973
          Length = 1094

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_005257436
          Length = 1120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 60 AARVRCE 66
>XP_005252669
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_006717572
          Length = 1003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005252667
          Length = 1052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005252666
          Length = 1057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005252665
          Length = 1068

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005252663
          Length = 1084

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005252662
          Length = 1084

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AARLRCQ 9
          AAR+RC+
Sbjct: 77 AARVRCE 83
>XP_005262946
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ARLRCQ 9
          AR+RCQ
Sbjct: 67 ARIRCQ 72
>XP_005262945
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ARLRCQ 9
          AR+RCQ
Sbjct: 67 ARIRCQ 72
>NP_001120965
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1331 IEARLRC 1337
>NP_066187
          Length = 1872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1340 IEARLRC 1346
>NP_001139
          Length = 3957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1340 IEARLRC 1346
>NP_055897
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VAARLRC 8
           VAA LRC
Sbjct: 356 VAASLRC 362
>XP_006714257
          Length = 4145

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1349 IEARLRC 1355
>XP_006714256
          Length = 1901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1369 IEARLRC 1375
>XP_006714255
          Length = 1970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1357 IEARLRC 1363
>XP_005263005
          Length = 2019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1339 IEARLRC 1345
>XP_006714254
          Length = 2049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1369 IEARLRC 1375
>XP_006714253
          Length = 2069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1369 IEARLRC 1375
>XP_005263002
          Length = 4072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1307 IEARLRC 1313
>XP_005262999
          Length = 4147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1351 IEARLRC 1357
>XP_006714252
          Length = 4153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1357 IEARLRC 1363
>XP_006714251
          Length = 4165

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1369 IEARLRC 1375
>XP_006714250
          Length = 4190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VAARLRC 8
            + ARLRC
Sbjct: 1394 IEARLRC 1400
>NP_001186170
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AA L+C
Sbjct: 15 RIAAELKC 22
>NP_001153399
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KVAARLRC 8
           +VAA L+C
Sbjct: 266 QVAAHLKC 273
>NP_996985
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KVAARLRC 8
           +VAA L+C
Sbjct: 336 QVAAHLKC 343
>NP_001153401
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KVAARLRC 8
           +VAA L+C
Sbjct: 317 QVAAHLKC 324
>NP_003928
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AA L+C
Sbjct: 15 RIAAELKC 22
>NP_659407
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AARL C
Sbjct: 5  ELAARLNC 12
>XP_006724591
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AARL C
Sbjct: 5  ELAARLNC 12
>XP_006724590
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AARL C
Sbjct: 56 ELAARLNC 63
>XP_006724589
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AARL C
Sbjct: 56 ELAARLNC 63
>XP_005272646
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AARL C
Sbjct: 56 ELAARLNC 63
>NP_001028170
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KVAARLRC 8
          ++AA L+C
Sbjct: 15 RIAAELKC 22
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.133    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,024
Number of extensions: 430
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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