Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_036221                                                              16    5631
XP_006711818                                                           16    5631
XP_006711817                                                           16    5631
NP_004870                                                              16    7355
NP_001277064                                                           16    7355
NP_001077422                                                           16    7355
NP_071348                                                              16    7355
NP_060557                                                              16    7355
XP_005271879                                                           16    7355
XP_006712132                                                           16    7355
XP_006712131                                                           16    7355
XP_006712130                                                           16    7355
XP_006712129                                                           16    7355
XP_006712128                                                           16    7355
XP_006712127                                                           16    7355
XP_006712126                                                           16    7355
XP_006712125                                                           16    7355
XP_006712124                                                           16    7355
XP_006710825                                                           16    7355
NP_001162023                                                           16    7355
NP_001005207                                                           15    9605
NP_001191827                                                           15    9605
NP_653267                                                              15    9605
NP_056109                                                              15    9605
NP_612470                                                              15    9605
XP_005257447                                                           15    9605
XP_005257446                                                           15    9605
XP_005257445                                                           15    9605
XP_005257444                                                           15    9605
XP_005257443                                                           15    9605
XP_005257442                                                           15    9605
>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTSLFSALI 9
           KT+LFSALI
Sbjct: 596 KTNLFSALI 604
>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTSLFSALI 9
           KT+LFSALI
Sbjct: 615 KTNLFSALI 623
>NP_036221
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KTSLFSALI 9
           +TSLFS+++
Sbjct: 248 RTSLFSSIL 256
>XP_006711818
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  KTSLFSALI 9
          +TSLFS+++
Sbjct: 69 RTSLFSSIL 77
>XP_006711817
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  KTSLFSALI 9
          +TSLFS+++
Sbjct: 69 RTSLFSSIL 77
>NP_004870
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TSLFSAL 8
           TS+FSAL
Sbjct: 123 TSIFSAL 129
>NP_001277064
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TSLFSAL 8
           TS+FSAL
Sbjct: 109 TSIFSAL 115
>NP_001077422
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>NP_071348
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>NP_060557
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           KTSLFS+
Sbjct: 430 KTSLFSS 436
>XP_005271879
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLFSALI 9
          SLFSAL+
Sbjct: 10 SLFSALV 16
>XP_006712132
          Length = 1136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TSLFSALI 9
           T LFSALI
Sbjct: 437 TLLFSALI 444
>XP_006712131
          Length = 1453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>XP_006712130
          Length = 1831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1132 TLLFSALI 1139
>XP_006712129
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1133 TLLFSALI 1140
>XP_006712128
          Length = 1879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>XP_006712127
          Length = 1909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>XP_006712126
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1214 TLLFSALI 1221
>XP_006712125
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1253 TLLFSALI 1260
>XP_006712124
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    TSLFSALI 9
            T LFSALI
Sbjct: 1254 TLLFSALI 1261
>XP_006710825
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           KTSLFS+
Sbjct: 425 KTSLFSS 431
>NP_001162023
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           KTSLFS+
Sbjct: 390 KTSLFSS 396
>NP_001005207
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>NP_001191827
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLFSALI 9
           SLFSAL+
Sbjct: 149 SLFSALL 155
>NP_653267
          Length = 4753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KTSLFSALI 9
            +TSL SAL+
Sbjct: 1567 QTSLLSALL 1575
>NP_056109
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>NP_612470
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLFSALI 9
           SLFSAL+
Sbjct: 175 SLFSALL 181
>XP_005257447
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257446
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257445
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257444
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 676 QTSLFSA 682
>XP_005257443
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 676 QTSLFSA 682
>XP_005257442
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KTSLFSA 7
           +TSLFSA
Sbjct: 710 QTSLFSA 716
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.132    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,639
Number of extensions: 446
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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