Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_078966                                                              16    5631
XP_006723004                                                           16    5631
NP_005427                                                              16    7355
NP_005319                                                              15    9605
NP_001186209                                                           15    9605
NP_005320                                                              15    9605
NP_001094064                                                           15    9605
NP_060189                                                              15    9605
XP_005255978                                                           15    9605
XP_005255977                                                           15    9605
XP_005265303                                                           15    9605
XP_005265302                                                           15    9605
>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTLAVNFQI 9
           KTLAVNF+I
Sbjct: 241 KTLAVNFRI 249
>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTLAVNFQI 9
           KTLAVNF+I
Sbjct: 241 KTLAVNFRI 249
>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTLAVNFQI 9
           KTLAVNF+I
Sbjct: 241 KTLAVNFRI 249
>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTLAVNFQI 9
           KTLAVNF+I
Sbjct: 241 KTLAVNFRI 249
>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KTLAVNFQI 9
           KTLAVNF+I
Sbjct: 241 KTLAVNFRI 249
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     KTLAVNFQI 9
             KTL +NF I
Sbjct: 14075 KTLTLNFTI 14083
>XP_006723004
          Length = 6443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KTLAVNFQI 9
            KTL +NF I
Sbjct: 6011 KTLTLNFTI 6019
>NP_005427
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KTLAVNFQ 8
           +TLAVN++
Sbjct: 128 ETLAVNYE 135
>NP_005319
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KTLAVNF 7
           KT+ VNF
Sbjct: 469 KTIVVNF 475
>NP_001186209
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KTLAVNF 7
           KT+ VNF
Sbjct: 472 KTIVVNF 478
>NP_005320
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KTLAVNF 7
           KT+ VNF
Sbjct: 472 KTIVVNF 478
>NP_001094064
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KTLAVNFQ 8
           KT++VN Q
Sbjct: 738 KTISVNIQ 745
>NP_060189
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KTLAVNFQ 8
           KT++VN Q
Sbjct: 738 KTISVNIQ 745
>XP_005255978
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KTLAVNF 7
           KT+ VNF
Sbjct: 472 KTIVVNF 478
>XP_005255977
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KTLAVNF 7
           KT+ VNF
Sbjct: 472 KTIVVNF 478
>XP_005265303
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KTLAVNFQ 8
           KT++VN Q
Sbjct: 738 KTISVNIQ 745
>XP_005265302
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KTLAVNFQ 8
           KT++VN Q
Sbjct: 738 KTISVNIQ 745
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.136    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 331,667
Number of extensions: 399
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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