Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_857597                                                              17    3301
NP_001940                                                              17    4312
NP_001036083                                                           17    4312
NP_005475                                                              17    4312
XP_005267304                                                           17    4312
XP_005248923                                                           17    4312
XP_005248922                                                           17    4312
XP_005250515                                                           16    5631
XP_005250514                                                           16    5631
NP_061877                                                              16    5631
NP_066970                                                              16    5631
NP_878315                                                              16    7355
NP_699165                                                              16    7355
NP_004082                                                              16    7355
NP_001273983                                                           16    7355
NP_003430                                                              16    7355
NP_001273984                                                           16    7355
XP_006716175                                                           16    7355
XP_005245779                                                           16    7355
XP_005245778                                                           16    7355
XP_005245777                                                           16    7355
XP_005245776                                                           16    7355
XP_005245775                                                           16    7355
XP_005245774                                                           16    7355
NP_005830                                                              16    7355
NP_004706                                                              15    9605
NP_001189433                                                           15    9605
NP_430255                                                              15    9605
NP_733468                                                              15    9605
NP_653091                                                              15    9605
NP_001278203                                                           15    9605
NP_116244                                                              15    9605
NP_057371                                                              15    9605
NP_055712                                                              15    9605
NP_001138837                                                           15    9605
NP_001273148                                                           15    9605
NP_004062                                                              15    9605
NP_065973                                                              15    9605
NP_001002838                                                           15    9605
NP_443139                                                              15    9605
NP_073752                                                              15    9605
NP_071918                                                              15    9605
NP_055445                                                              15    9605
XP_003960381                                                           15    9605
XP_006724657                                                           15    9605
XP_006724656                                                           15    9605
XP_006722637                                                           15    9605
XP_005266839                                                           15    9605
XP_006721838                                                           15    9605
XP_006721837                                                           15    9605
XP_005255053                                                           15    9605
XP_006720709                                                           15    9605
XP_005254660                                                           15    9605
XP_005254649                                                           15    9605
XP_005254648                                                           15    9605
XP_006719284                                                           15    9605
XP_006719283                                                           15    9605
XP_006719282                                                           15    9605
XP_006713898                                                           15    9605
XP_003403469                                                           15    9605
XP_006713897                                                           15    9605
XP_006712449                                                           15    9605
XP_005245936                                                           15    9605
XP_005245935                                                           15    9605
XP_005245933                                                           15    9605
XP_005245934                                                           15    9605
XP_005245932                                                           15    9605
XP_006710216                                                           15    9605
XP_003403820                                                           15    9605
XP_006710215                                                           15    9605
NP_001155879                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KSPIQKTRR 9
            KS IQKTRR
Sbjct: 2924 KSQIQKTRR 2932
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KSPIQKTRR 9
            KS IQKTRR
Sbjct: 2719 KSQIQKTRR 2727
>NP_857597
          Length = 1349

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           KSPI KT++
Sbjct: 250 KSPIYKTKQ 258
>NP_001940
          Length = 465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           KSP +KTR
Sbjct: 171 KSPSEKTR 178
>NP_001036083
          Length = 570

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SPIQKTRR 9
          SP +KTRR
Sbjct: 34 SPAKKTRR 41
>NP_005475
          Length = 583

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SPIQKTRR 9
          SP +KTRR
Sbjct: 34 SPAKKTRR 41
>XP_005267304
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SPIQKTRR 9
          SP +KTRR
Sbjct: 34 SPAKKTRR 41
>XP_005248923
          Length = 335

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          KSP +KTR
Sbjct: 41 KSPSEKTR 48
>XP_005248922
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          KSP +KTR
Sbjct: 46 KSPSEKTR 53
>XP_005250515
          Length = 1083

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSPIQK 6
           KSPIQK
Sbjct: 523 KSPIQK 528
>XP_005250514
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSPIQK 6
           KSPIQK
Sbjct: 523 KSPIQK 528
>NP_061877
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSPIQK 6
           KSPIQK
Sbjct: 523 KSPIQK 528
>NP_066970
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  KSPIQKTRR 9
          ++P++K+RR
Sbjct: 26 RAPVKKSRR 34
>NP_878315
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSPIQKTRR 9
           K+PIQK  R
Sbjct: 840 KTPIQKPPR 848
>NP_699165
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSPIQKTRR 9
           K+PIQK  R
Sbjct: 845 KTPIQKPPR 853
>NP_004082
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           KSP +KTR
Sbjct: 122 KSPGEKTR 129
>NP_001273983
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           K+P +KTR+
Sbjct: 281 KNPEEKTRK 289
>NP_003430
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           K+P +KTR+
Sbjct: 317 KNPEEKTRK 325
>NP_001273984
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           K+P +KTR+
Sbjct: 104 KNPEEKTRK 112
>XP_006716175
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           K+P +KTR+
Sbjct: 317 KNPEEKTRK 325
>XP_005245779
          Length = 888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 350 SPPRKTRR 357
>XP_005245778
          Length = 902

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>XP_005245777
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>XP_005245776
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>XP_005245775
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>XP_005245774
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>NP_005830
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP +KTRR
Sbjct: 380 SPPRKTRR 387
>NP_004706
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PIQKTR 8
           PI+KTR
Sbjct: 650 PIEKTR 655
>NP_001189433
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PIQKTR 8
           PI+KTR
Sbjct: 531 PIEKTR 536
>NP_430255
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PIQKTR 8
           PI+KTR
Sbjct: 650 PIEKTR 655
>NP_733468
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KSPIQKT 7
           KSPI+K+
Sbjct: 836 KSPIEKS 842
>NP_653091
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KSPIQKT 7
           KSPI+K+
Sbjct: 810 KSPIEKS 816
>NP_001278203
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           KSP+ +TR+
Sbjct: 136 KSPLGETRQ 144
>NP_116244
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           KSP+ +TR+
Sbjct: 193 KSPLGETRQ 201
>NP_057371
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 503 KTPAKKTR 510
>NP_055712
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P+QK +
Sbjct: 231 KAPVQKAK 238
>NP_001138837
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P+QK +
Sbjct: 231 KAPVQKAK 238
>NP_001273148
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PIQKTRR 9
           P QKT+R
Sbjct: 280 PCQKTKR 286
>NP_004062
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSPIQKTRR 9
           K  IQKTR+
Sbjct: 400 KHMIQKTRK 408
>NP_065973
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPIQKTR 8
           +PI+KTR
Sbjct: 489 TPIKKTR 495
>NP_001002838
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPIQKTR 8
           +PI+KTR
Sbjct: 489 TPIKKTR 495
>NP_443139
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PIQKTRR 9
           P QKT+R
Sbjct: 768 PCQKTKR 774
>NP_073752
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PIQKTRR 9
           P+Q+TR+
Sbjct: 369 PVQRTRQ 375
>NP_071918
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP QKT++
Sbjct: 400 SPTQKTQK 407
>NP_055445
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           +SP++ TR+
Sbjct: 333 RSPLEATRK 341
>XP_003960381
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_006724657
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPIQKTR 8
           +PI+KTR
Sbjct: 489 TPIKKTR 495
>XP_006724656
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPIQKTR 8
           +PI+KTR
Sbjct: 489 TPIKKTR 495
>XP_006722637
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PIQKTR 8
           PI+KTR
Sbjct: 549 PIEKTR 554
>XP_005266839
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PIQKTR 8
           PI+KTR
Sbjct: 650 PIEKTR 655
>XP_006721838
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P+QK +
Sbjct: 231 KAPVQKAK 238
>XP_006721837
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P+QK +
Sbjct: 231 KAPVQKAK 238
>XP_005255053
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KSPIQKTRR 9
           +SP++ TR+
Sbjct: 333 RSPLEATRK 341
>XP_006720709
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PIQKTRR 9
           P+Q+TR+
Sbjct: 98  PVQRTRQ 104
>XP_005254660
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PIQKTRR 9
           P+Q+TR+
Sbjct: 369 PVQRTRQ 375
>XP_005254649
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP QKT++
Sbjct: 423 SPTQKTQK 430
>XP_005254648
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPIQKTRR 9
           SP QKT++
Sbjct: 423 SPTQKTQK 430
>XP_006719284
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PIQKTRR 9
           P QKT+R
Sbjct: 366 PCQKTKR 372
>XP_006719283
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PIQKTRR 9
           P QKT+R
Sbjct: 658 PCQKTKR 664
>XP_006719282
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PIQKTRR 9
           P QKT+R
Sbjct: 658 PCQKTKR 664
>XP_006713898
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_003403469
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_006713897
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_006712449
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    PIQKTRR 9
            P+Q TRR
Sbjct: 1901 PLQATRR 1907
>XP_005245936
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 465 KTPAKKTR 472
>XP_005245935
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 503 KTPAKKTR 510
>XP_005245933
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 503 KTPAKKTR 510
>XP_005245934
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 503 KTPAKKTR 510
>XP_005245932
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSPIQKTR 8
           K+P +KTR
Sbjct: 503 KTPAKKTR 510
>XP_006710216
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_003403820
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>XP_006710215
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KSPIQKTR 8
          K+P+ KT+
Sbjct: 47 KTPVHKTK 54
>NP_001155879
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSPIQKTRR 9
           K  IQKTR+
Sbjct: 442 KHMIQKTRK 450
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.124    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 678,497
Number of extensions: 1475
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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