Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_057323                                                              17    4312
XP_005256732                                                           17    4312
NP_001273479                                                           16    5631
NP_001007528                                                           16    5631
NP_001139017                                                           16    5631
NP_004447                                                              16    7355
NP_694543                                                              16    7355
NP_001190177                                                           16    7355
NP_001190178                                                           16    7355
NP_001190176                                                           16    7355
NP_008919                                                              16    7355
NP_055928                                                              16    7355
NP_733751                                                              16    7355
NP_055504                                                              16    7355
NP_001277192                                                           16    7355
NP_056169                                                              16    7355
NP_055626                                                              16    7355
NP_055160                                                              16    7355
XP_005256618                                                           16    7355
XP_005256617                                                           16    7355
XP_006717405                                                           16    7355
XP_006717404                                                           16    7355
XP_006717403                                                           16    7355
XP_005263469                                                           16    7355
XP_005263468                                                           16    7355
XP_006716142                                                           16    7355
XP_005250088                                                           16    7355
XP_006716141                                                           16    7355
XP_005250085                                                           16    7355
XP_006716140                                                           16    7355
XP_005250084                                                           16    7355
XP_005250083                                                           16    7355
XP_005250082                                                           16    7355
XP_005250021                                                           16    7355
XP_006715950                                                           16    7355
XP_006715948                                                           16    7355
XP_005250020                                                           16    7355
XP_006715946                                                           16    7355
XP_005250019                                                           16    7355
XP_006715469                                                           16    7355
XP_005266931                                                           16    7355
XP_006712687                                                           16    7355
XP_006712686                                                           16    7355
XP_006712685                                                           16    7355
XP_006712684                                                           16    7355
XP_006712683                                                           16    7355
XP_006712682                                                           16    7355
XP_006712681                                                           16    7355
XP_005246730                                                           16    7355
XP_005246729                                                           16    7355
XP_006712680                                                           16    7355
XP_006712679                                                           16    7355
NP_073592                                                              15    9605
NP_853514                                                              15    9605
NP_004648                                                              15    9605
XP_006718102                                                           15    9605
XP_006717298                                                           15    9605
>NP_057323
          Length = 3530

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLVSSHRQ 9
            +LVS HRQ
Sbjct: 3383 NLVSQHRQ 3390
>XP_005256732
          Length = 3531

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLVSSHRQ 9
            +LVS HRQ
Sbjct: 3384 NLVSQHRQ 3391
>NP_001273479
          Length = 153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLVSSHRQ 9
          SLVS+H Q
Sbjct: 90 SLVSAHNQ 97
>NP_001007528
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSLVSSHRQ 9
           KSLV  H+Q
Sbjct: 304 KSLVKLHKQ 312
>NP_001139017
          Length = 154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLVSSHRQ 9
           SLV SHR+
Sbjct: 101 SLVGSHRR 108
>NP_004447
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>NP_694543
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>NP_001190177
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>NP_001190178
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>NP_001190176
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>NP_008919
          Length = 967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSLVSSHR 8
           K  VSSHR
Sbjct: 251 KRFVSSHR 258
>NP_055928
          Length = 2961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSLVSSHR 8
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>NP_733751
          Length = 4911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4126 LVSSHR 4131
>NP_055504
          Length = 2186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1601 KSIVRSHLQ 1609
>NP_001277192
          Length = 2180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1595 KSIVRSHLQ 1603
>NP_056169
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSLVSSHRQ 9
           K LVS +RQ
Sbjct: 167 KELVSKYRQ 175
>NP_055626
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>NP_055160
          Length = 2279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSLVSSHR 8
          +S VSSHR
Sbjct: 7  RSSVSSHR 14
>XP_005256618
          Length = 2962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSLVSSHR 8
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>XP_005256617
          Length = 2966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSLVSSHR 8
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>XP_006717405
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>XP_006717404
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>XP_006717403
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>XP_005263469
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>XP_005263468
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL+ SH++
Sbjct: 261 KSLLKSHQE 269
>XP_006716142
          Length = 4927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4142 LVSSHR 4147
>XP_005250088
          Length = 4928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4143 LVSSHR 4148
>XP_006716141
          Length = 4959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4174 LVSSHR 4179
>XP_005250085
          Length = 4979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4198 LVSSHR 4203
>XP_006716140
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250084
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250083
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250082
          Length = 4983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LVSSHR 8
            LVSSHR
Sbjct: 4198 LVSSHR 4203
>XP_005250021
          Length = 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 47 KSMFSSNRQ 55
>XP_006715950
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 47 KSMFSSNRQ 55
>XP_006715948
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>XP_005250020
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 47 KSMFSSNRQ 55
>XP_006715946
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 39 KSMFSSNRQ 47
>XP_005250019
          Length = 754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSLVSSHRQ 9
          KS+ SS+RQ
Sbjct: 47 KSMFSSNRQ 55
>XP_006715469
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLVSSHRQ 9
          SL+SSH++
Sbjct: 71 SLISSHQR 78
>XP_005266931
          Length = 1283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVSSHRQ 9
           SL+SSH++
Sbjct: 119 SLISSHQR 126
>XP_006712687
          Length = 2166

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1605 KSIVRSHLQ 1613
>XP_006712686
          Length = 2173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_006712685
          Length = 2175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_006712684
          Length = 2189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1595 KSIVRSHLQ 1603
>XP_006712683
          Length = 2195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1601 KSIVRSHLQ 1609
>XP_006712682
          Length = 2199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1605 KSIVRSHLQ 1613
>XP_006712681
          Length = 2199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_005246730
          Length = 2199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_005246729
          Length = 2201

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_006712680
          Length = 2206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>XP_006712679
          Length = 2208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KSLVSSHRQ 9
            KS+V SH Q
Sbjct: 1614 KSIVRSHLQ 1622
>NP_073592
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSLVSSHRQ 9
          KSLV +H Q
Sbjct: 19 KSLVVAHAQ 27
>NP_853514
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SLVSSH 7
            SLVSSH
Sbjct: 1042 SLVSSH 1047
>NP_004648
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSLVSSHRQ 9
           KSL S+H++
Sbjct: 273 KSLTSNHQK 281
>XP_006718102
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSLVSSHRQ 9
           K+ VSSH Q
Sbjct: 826 KAKVSSHSQ 834
>XP_006717298
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSLVSSHRQ 9
          KSLV +H Q
Sbjct: 19 KSLVVAHAQ 27
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.111    0.271 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 552,853
Number of extensions: 878
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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