Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     869
NP_036462                                                              19     869
NP_001243397                                                           19     869
XP_005269721                                                           19     869
NP_001094891                                                           18    1482
NP_004320                                                              18    1935
NP_004882                                                              18    1935
NP_001124388                                                           17    2528
NP_004603                                                              17    2528
NP_001104537                                                           17    2528
NP_001096                                                              17    2528
NP_001104502                                                           17    2528
NP_660302                                                              17    2528
NP_001104501                                                           17    2528
NP_001104503                                                           17    2528
NP_001243721                                                           17    2528
NP_001243722                                                           17    2528
NP_001243723                                                           17    2528
NP_001194                                                              17    2528
NP_001004441                                                           17    2528
NP_064732                                                              17    2528
NP_001607                                                              17    2528
NP_001097                                                              17    2528
NP_004293                                                              17    2528
NP_064733                                                              17    2528
NP_001265509                                                           17    2528
NP_001265508                                                           17    2528
XP_006719748                                                           17    2528
XP_005252207                                                           17    2528
XP_006714662                                                           17    2528
XP_006714355                                                           17    2528
XP_005265640                                                           17    2528
XP_005263900                                                           17    2528
XP_006712888                                                           17    2528
XP_005246996                                                           17    2528
XP_005246997                                                           17    2528
NP_996888                                                              17    3301
NP_009053                                                              17    3301
NP_001263302                                                           17    3301
NP_659469                                                              17    4312
NP_001104508                                                           17    4312
NP_001274079                                                           17    4312
XP_005250270                                                           17    4312
XP_005250269                                                           17    4312
XP_005250266                                                           17    4312
XP_006715960                                                           17    4312
XP_005250265                                                           17    4312
XP_005250264                                                           17    4312
XP_005250262                                                           17    4312
NP_006276                                                              16    7355
NP_954984                                                              15    9605
NP_001157755                                                           15    9605
NP_001106674                                                           15    9605
NP_001106673                                                           15    9605
NP_679211                                                              15    9605
NP_001157753                                                           15    9605
NP_620636                                                              15    9605
NP_003062                                                              15    9605
NP_001139806                                                           15    9605
XP_006719484                                                           15    9605
XP_006719483                                                           15    9605
XP_006719482                                                           15    9605
XP_006719481                                                           15    9605
XP_006719480                                                           15    9605
XP_006719479                                                           15    9605
XP_006719478                                                           15    9605
XP_006719477                                                           15    9605
XP_006719476                                                           15    9605
XP_006719475                                                           15    9605
XP_006715737                                                           15    9605
XP_006715382                                                           15    9605
XP_005247781                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKNILLR
Sbjct: 467 KSKNILLR 474
>NP_036462
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKNILLR
Sbjct: 759 KSKNILLR 766
>NP_001243397
          Length = 1890

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKNILLR
Sbjct: 576 KSKNILLR 583
>XP_005269721
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKNILLR
Sbjct: 759 KSKNILLR 766
>NP_001094891
          Length = 1022

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKNI+LR
Sbjct: 536 KSKNIILR 543
>NP_004320
          Length = 532

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 364 KSKNILIKK 372
>NP_004882
          Length = 65

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  KSKNILLR 8
          KSKNIL+R
Sbjct: 12 KSKNILVR 19
>NP_001124388
          Length = 426

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 258 KSKNILVKK 266
>NP_004603
          Length = 503

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 335 KSKNILVKK 343
>NP_001104537
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 338 KSKNILVKK 346
>NP_001096
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 338 KSKNILVKK 346
>NP_001104502
          Length = 413

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 245 KSKNILVKK 253
>NP_660302
          Length = 493

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 325 KSKNILVKK 333
>NP_001104501
          Length = 443

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 275 KSKNILVKK 283
>NP_001104503
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 168 KSKNILVKK 176
>NP_001243721
          Length = 502

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 334 KSKNILVKK 342
>NP_001243722
          Length = 532

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 364 KSKNILVKK 372
>NP_001243723
          Length = 502

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 334 KSKNILVKK 342
>NP_001194
          Length = 502

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 334 KSKNILVKK 342
>NP_001004441
          Length = 514

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSKNILLRR 9
           KSK +LLRR
Sbjct: 492 KSKKMLLRR 500
>NP_064732
          Length = 453

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 285 KSKNILVKK 293
>NP_001607
          Length = 513

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 324 KSKNVLLK 331
>NP_001097
          Length = 512

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 323 KSKNVLLK 330
>NP_004293
          Length = 505

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 337 KSKNILVKK 345
>NP_064733
          Length = 546

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 378 KSKNILVKK 386
>NP_001265509
          Length = 405

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 216 KSKNVLLK 223
>NP_001265508
          Length = 513

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 324 KSKNVLLK 331
>XP_006719748
          Length = 545

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 377 KSKNILVKK 385
>XP_005252207
          Length = 507

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 339 KSKNILVKK 347
>XP_006714662
          Length = 514

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSKNILLRR 9
           KSK +LLRR
Sbjct: 492 KSKKMLLRR 500
>XP_006714355
          Length = 502

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 334 KSKNILVKK 342
>XP_005265640
          Length = 533

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 344 KSKNVLLK 351
>XP_005263900
          Length = 361

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           KSKN+LL+
Sbjct: 324 KSKNVLLK 331
>XP_006712888
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 338 KSKNILVKK 346
>XP_005246996
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 338 KSKNILVKK 346
>XP_005246997
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKNILLRR 9
           KSKNIL+++
Sbjct: 338 KSKNILVKK 346
>NP_996888
          Length = 251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           K+KN+LLR
Sbjct: 227 KNKNLLLR 234
>NP_009053
          Length = 310

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           K+KN+LLR
Sbjct: 286 KNKNLLLR 293
>NP_001263302
          Length = 310

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSKNILLR 8
           K+KN+LLR
Sbjct: 286 KNKNLLLR 293
>NP_659469
          Length = 735

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 70 KLKNILLR 77
>NP_001104508
          Length = 690

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 70 KLKNILLR 77
>NP_001274079
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 70 KLKNILLR 77
>XP_005250270
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 70 KLKNILLR 77
>XP_005250269
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSKNILLR 8
           K KNILLR
Sbjct: 160 KLKNILLR 167
>XP_005250266
          Length = 735

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 70 KLKNILLR 77
>XP_006715960
          Length = 737

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KSKNILLR 8
          K KNILLR
Sbjct: 72 KLKNILLR 79
>XP_005250265
          Length = 780

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSKNILLR 8
           K KNILLR
Sbjct: 160 KLKNILLR 167
>XP_005250264
          Length = 792

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSKNILLR 8
           K KNILLR
Sbjct: 160 KLKNILLR 167
>XP_005250262
          Length = 825

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSKNILLR 8
           K KNILLR
Sbjct: 160 KLKNILLR 167
>NP_006276
          Length = 626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKNILLRR 9
           SKN L+RR
Sbjct: 178 SKNCLVRR 185
>NP_954984
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>NP_001157755
          Length = 109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KNILLR 8
          KNILLR
Sbjct: 81 KNILLR 86
>NP_001106674
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 808 KSKNIL 813
>NP_001106673
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>NP_679211
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KNILLR 8
           KNILLR
Sbjct: 537 KNILLR 542
>NP_001157753
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KNILLR 8
           KNILLR
Sbjct: 536 KNILLR 541
>NP_620636
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KNILLRR 9
           KNI LRR
Sbjct: 638 KNITLRR 644
>NP_003062
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KNILLRR 9
           KNI LRR
Sbjct: 638 KNITLRR 644
>NP_001139806
          Length = 1562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1439 KSKNIL 1444
>XP_006719484
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>XP_006719483
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>XP_006719482
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>XP_006719481
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KSKNIL 6
           KSKNIL
Sbjct: 98  KSKNIL 103
>XP_006719480
          Length = 2035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1914 KSKNIL 1919
>XP_006719479
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1938 KSKNIL 1943
>XP_006719478
          Length = 2078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1961 KSKNIL 1966
>XP_006719477
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1961 KSKNIL 1966
>XP_006719476
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1961 KSKNIL 1966
>XP_006719475
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1961 KSKNIL 1966
>XP_006715737
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KSKNIL 6
            KSKNIL
Sbjct: 1226 KSKNIL 1231
>XP_006715382
          Length = 109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KNILLR 8
          KNILLR
Sbjct: 81 KNILLR 86
>XP_005247781
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KNILLRR 9
           KNI LRR
Sbjct: 637 KNITLRR 643
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.139    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,037
Number of extensions: 867
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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