Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_001001670                                                           18    1935
NP_036320                                                              17    3301
NP_001264125                                                           17    3301
NP_057102                                                              17    3301
XP_006716635                                                           17    3301
XP_005250999                                                           17    3301
XP_005250997                                                           17    3301
XP_005250996                                                           17    3301
XP_005250995                                                           17    3301
XP_005250994                                                           17    3301
XP_005250993                                                           17    3301
XP_005250992                                                           17    3301
XP_005250991                                                           17    3301
XP_005250990                                                           17    3301
XP_005250989                                                           17    3301
XP_005250988                                                           17    3301
XP_005250987                                                           17    3301
NP_001136272                                                           16    5631
NP_002102                                                              16    5631
NP_775836                                                              16    5631
NP_001034976                                                           16    5631
XP_006715831                                                           16    5631
XP_005249890                                                           16    5631
XP_006715830                                                           16    5631
XP_005249889                                                           16    5631
XP_005249888                                                           16    5631
XP_005249887                                                           16    5631
XP_006715829                                                           16    5631
XP_005249716                                                           16    5631
XP_005249717                                                           16    5631
XP_006715732                                                           16    5631
NP_001093167                                                           16    5631
NP_055448                                                              16    5631
NP_003283                                                              16    7355
NP_612429                                                              16    7355
XP_005267356                                                           16    7355
XP_005245528                                                           16    7355
NP_001229295                                                           15    9605
NP_542400                                                              15    9605
NP_000375                                                              15    9605
NP_001167558                                                           15    9605
NP_858045                                                              15    9605
NP_006525                                                              15    9605
NP_001167559                                                           15    9605
XP_005277843                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 777 SKADVSSS 784
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 777 SKADVSSS 784
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SKADVSSS 9
           SKADVSSS
Sbjct: 778 SKADVSSS 785
>NP_001001670
          Length = 1576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           KSKAD+S+S
Sbjct: 930 KSKADLSTS 938
>NP_036320
          Length = 378

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSKADVSSS 9
           K K+DVSSS
Sbjct: 217 KRKSDVSSS 225
>NP_001264125
          Length = 991

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 295 KNEADISSS 303
>NP_057102
          Length = 1017

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 321 KNEADISSS 329
>XP_006716635
          Length = 573

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 321 KNEADISSS 329
>XP_005250999
          Length = 578

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 326 KNEADISSS 334
>XP_005250997
          Length = 913

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 217 KNEADISSS 225
>XP_005250996
          Length = 913

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 217 KNEADISSS 225
>XP_005250995
          Length = 929

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 326 KNEADISSS 334
>XP_005250994
          Length = 991

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 295 KNEADISSS 303
>XP_005250993
          Length = 992

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 296 KNEADISSS 304
>XP_005250992
          Length = 992

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 296 KNEADISSS 304
>XP_005250991
          Length = 1017

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 321 KNEADISSS 329
>XP_005250990
          Length = 1018

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 322 KNEADISSS 330
>XP_005250989
          Length = 1021

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 325 KNEADISSS 333
>XP_005250988
          Length = 1022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 326 KNEADISSS 334
>XP_005250987
          Length = 1022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           K++AD+SSS
Sbjct: 326 KNEADISSS 334
>NP_001136272
          Length = 3144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SKADVSSS 9
            S ADVSSS
Sbjct: 1341 SSADVSSS 1348
>NP_002102
          Length = 3144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KSKADVSSS 9
           +S++DVSSS
Sbjct: 458 ESRSDVSSS 466
>NP_775836
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 835 KEPADVSSS 843
>NP_001034976
          Length = 480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSKADVSSS 9
           +SKA +SSS
Sbjct: 208 RSKASISSS 216
>XP_006715831
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 531 KEPADVSSS 539
>XP_005249890
          Length = 662

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 627 KEPADVSSS 635
>XP_006715830
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 722 KEPADVSSS 730
>XP_005249889
          Length = 810

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 775 KEPADVSSS 783
>XP_005249888
          Length = 827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 792 KEPADVSSS 800
>XP_005249887
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 835 KEPADVSSS 843
>XP_006715829
          Length = 875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 840 KEPADVSSS 848
>XP_005249716
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 835 KEPADVSSS 843
>XP_005249717
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 557 KEPADVSSS 565
>XP_006715732
          Length = 646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 611 KEPADVSSS 619
>NP_001093167
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KSKADVSSS 9
           K  ADVSSS
Sbjct: 835 KEPADVSSS 843
>NP_055448
          Length = 1173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    KSKADVSSS 9
            KSKA +SSS
Sbjct: 1009 KSKAIISSS 1017
>NP_003283
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKADVSSS 9
           S AD+SSS
Sbjct: 522 SSADISSS 529
>NP_612429
          Length = 5795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KSKADVS 7
            K+KADVS
Sbjct: 4162 KAKADVS 4168
>XP_005267356
          Length = 5695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KSKADVS 7
            K+KADVS
Sbjct: 4062 KAKADVS 4068
>XP_005245528
          Length = 2439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKADVSSS 9
           S AD+SSS
Sbjct: 598 SSADISSS 605
>NP_001229295
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SKADVSSS 9
           S ADVSSS
Sbjct: 167 SVADVSSS 174
>NP_542400
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SKADVSSS 9
           S ADVSSS
Sbjct: 167 SVADVSSS 174
>NP_000375
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KSKADVSSS 9
            KSK  VSSS
Sbjct: 3449 KSKPTVSSS 3457
>NP_001167558
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KADVSSS 9
           KADVSS+
Sbjct: 97  KADVSST 103
>NP_858045
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KADVSSS 9
           KADVSS+
Sbjct: 97  KADVSST 103
>NP_006525
          Length = 1420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KADVSSS 9
           KADVSS+
Sbjct: 97  KADVSST 103
>NP_001167559
          Length = 1415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KADVSSS 9
           KADVSS+
Sbjct: 97  KADVSST 103
>XP_005277843
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SKADVSSS 9
           S ADVSSS
Sbjct: 167 SVADVSSS 174
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.270   0.0875    0.180 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,669
Number of extensions: 580
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)

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