Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    2528
XP_006716142                                                           17    2528
XP_005250088                                                           17    2528
XP_006716141                                                           17    2528
XP_005250085                                                           17    2528
XP_006716140                                                           17    2528
XP_005250084                                                           17    2528
XP_005250083                                                           17    2528
XP_005250082                                                           17    2528
NP_005616                                                              16    5631
NP_001007071                                                           16    5631
NP_001007068                                                           16    5631
NP_001007069                                                           16    5631
NP_001007070                                                           16    5631
XP_005256599                                                           16    5631
XP_005251337                                                           16    5631
NP_001135976                                                           16    7355
NP_002660                                                              16    7355
NP_001188493                                                           16    7355
NP_001135975                                                           16    7355
NP_775835                                                              16    7355
NP_055540                                                              16    7355
NP_002310                                                              16    7355
NP_001276863                                                           16    7355
XP_005262372                                                           16    7355
XP_005262371                                                           16    7355
XP_005250403                                                           16    7355
XP_005250285                                                           16    7355
XP_006715971                                                           16    7355
XP_006715970                                                           16    7355
NP_821075                                                              15    9605
NP_443083                                                              15    9605
NP_821074                                                              15    9605
NP_001230405                                                           15    9605
NP_004163                                                              15    9605
NP_004161                                                              15    9605
NP_001160167                                                           15    9605
NP_001276868                                                           15    9605
NP_001276869                                                           15    9605
NP_001136438                                                           15    9605
NP_277039                                                              15    9605
NP_071903                                                              15    9605
XP_006722610                                                           15    9605
XP_006719952                                                           15    9605
XP_006719951                                                           15    9605
XP_005266643                                                           15    9605
XP_005249615                                                           15    9605
XP_005249612                                                           15    9605
XP_006714551                                                           15    9605
XP_005248399                                                           15    9605
XP_005270465                                                           15    9605
>NP_733751
          Length = 4911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 913 KSGIGAVVL 921
>XP_006716142
          Length = 4927

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_005250088
          Length = 4928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_006716141
          Length = 4959

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_005250085
          Length = 4979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_006716140
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_005250084
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>XP_005250083
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 913 KSGIGAVVL 921
>XP_005250082
          Length = 4983

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGIRAVVL 9
           KSGI AVVL
Sbjct: 914 KSGIGAVVL 922
>NP_005616
          Length = 298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 109 KQGIREVIL 117
>NP_001007071
          Length = 297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 108 KQGIREVIL 116
>NP_001007068
          Length = 298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 109 KQGIREVIL 117
>NP_001007069
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 103 KQGIREVIL 111
>NP_001007070
          Length = 297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 108 KQGIREVIL 116
>XP_005256599
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSGIRAVVL 9
          K+GIRA V+
Sbjct: 12 KAGIRAAVV 20
>XP_005251337
          Length = 318

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIR V+L
Sbjct: 129 KQGIREVIL 137
>NP_001135976
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSGIRAVVL 9
           +SG+RA++L
Sbjct: 952 ESGVRALML 960
>NP_002660
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K  +RAVVL
Sbjct: 372 KKSVRAVVL 380
>NP_001188493
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K  +RAVVL
Sbjct: 363 KKSVRAVVL 371
>NP_001135975
          Length = 1103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KSGIRAVVL 9
            +SG+RA++L
Sbjct: 1032 ESGVRALML 1040
>NP_775835
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R VVL
Sbjct: 734 SGVRQVVL 741
>NP_055540
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSGIRAVVL 9
           +SG+RA++L
Sbjct: 952 ESGVRALML 960
>NP_002310
          Length = 683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 435 KPGLRAVV 442
>NP_001276863
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 435 KPGLRAVV 442
>XP_005262372
          Length = 1027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSGIRAVVL 9
           +SG+RA++L
Sbjct: 956 ESGVRALML 964
>XP_005262371
          Length = 1107

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KSGIRAVVL 9
            +SG+RA++L
Sbjct: 1036 ESGVRALML 1044
>XP_005250403
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 396 KPGLRAVV 403
>XP_005250285
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R VVL
Sbjct: 735 SGVRQVVL 742
>XP_006715971
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R VVL
Sbjct: 735 SGVRQVVL 742
>XP_006715970
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R VVL
Sbjct: 735 SGVRQVVL 742
>NP_821075
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GIRAVVL 9
            G+RAVV+
Sbjct: 1036 GVRAVVM 1042
>NP_443083
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIRAVVL 9
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>NP_821074
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GIRAVVL 9
            G+RAVV+
Sbjct: 1044 GVRAVVM 1050
>NP_001230405
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GIRAVVL 9
            G+RAVV+
Sbjct: 1009 GVRAVVM 1015
>NP_004163
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 118 KMGMRAVV 125
>NP_004161
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSGIRAVV 8
          K G+RAVV
Sbjct: 89 KIGLRAVV 96
>NP_001160167
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 118 KMGMRAVV 125
>NP_001276868
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KSGIRAVV 8
          K G+RAVV
Sbjct: 72 KMGMRAVV 79
>NP_001276869
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 118 KMGMRAVV 125
>NP_001136438
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R V+L
Sbjct: 394 SGVRPVIL 401
>NP_277039
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SGIRAVVL 9
          SGI A+VL
Sbjct: 74 SGIAAIVL 81
>NP_071903
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIRA +L
Sbjct: 140 KKGIRARIL 148
>XP_006722610
          Length = 1967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGIRAVVL 9
           SG+R V+L
Sbjct: 437 SGVRPVIL 444
>XP_006719952
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIRAVVL 9
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>XP_006719951
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIRAVVL 9
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>XP_005266643
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GIRAVVL 9
            G+RAVV+
Sbjct: 1029 GVRAVVM 1035
>XP_005249615
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIRA +L
Sbjct: 140 KKGIRARIL 148
>XP_005249612
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGIRAVVL 9
           K GIRA +L
Sbjct: 140 KKGIRARIL 148
>XP_006714551
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 118 KMGMRAVV 125
>XP_005248399
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGIRAVV 8
           K G+RAVV
Sbjct: 118 KMGMRAVV 125
>XP_005270465
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SGIRAVVL 9
          SGI A+VL
Sbjct: 74 SGIAAIVL 81
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.141    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 364,450
Number of extensions: 500
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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