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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001156863                                                           16    5631
NP_653294                                                              16    5631
XP_005259813                                                           16    5631
XP_005259812                                                           16    5631
XP_006715347                                                           16    5631
XP_006715346                                                           16    5631
XP_006715345                                                           16    5631
NP_001254708                                                           16    7355
NP_001180481                                                           16    7355
NP_001273424                                                           16    7355
NP_062546                                                              16    7355
XP_006723248                                                           16    7355
XP_005258914                                                           16    7355
XP_005258915                                                           16    7355
XP_006720675                                                           16    7355
XP_006720674                                                           16    7355
XP_006720672                                                           16    7355
XP_005254605                                                           16    7355
XP_005254604                                                           16    7355
XP_005249007                                                           16    7355
NP_001012458                                                           16    7355
NP_001073991                                                           15    9605
NP_000099                                                              15    9605
NP_001276680                                                           15    9605
NP_001276679                                                           15    9605
NP_001276681                                                           15    9605
NP_001136279                                                           15    9605
NP_859074                                                              15    9605
NP_071904                                                              15    9605
NP_001803                                                              15    9605
XP_005266561                                                           15    9605
XP_005266560                                                           15    9605
XP_005266559                                                           15    9605
XP_005273535                                                           15    9605
XP_006716393                                                           15    9605
XP_006716392                                                           15    9605
XP_006716391                                                           15    9605
XP_005273534                                                           15    9605
XP_006714128                                                           15    9605
XP_006714127                                                           15    9605
XP_005248234                                                           15    9605

>NP_001156863
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RSI+
Sbjct: 393 KSFSRRSIL 401



>NP_653294
          Length = 402

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+SRS +
Sbjct: 187 KSFSSRSYL 195



>XP_005259813
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+SRS +
Sbjct: 116 KSFSSRSYL 124



>XP_005259812
          Length = 402

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+SRS +
Sbjct: 187 KSFSSRSYL 195



>XP_006715347
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RSI+
Sbjct: 393 KSFSRRSIL 401



>XP_006715346
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RSI+
Sbjct: 393 KSFSRRSIL 401



>XP_006715345
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RSI+
Sbjct: 393 KSFSRRSIL 401



>NP_001254708
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 536 KSFTSRSAL 544




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 816 KSFTSRSTL 824



>NP_001180481
          Length = 1090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 568 KSFTSRSAL 576




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 848 KSFTSRSTL 856



>NP_001273424
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 848 KSFSSRS 854



>NP_062546
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 841 KSFSSRS 847



>XP_006723248
          Length = 1060

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 538 KSFTSRSAL 546




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 818 KSFTSRSTL 826



>XP_005258914
          Length = 1092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 570 KSFTSRSAL 578




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 850 KSFTSRSTL 858



>XP_005258915
          Length = 1092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 570 KSFTSRSAL 578




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSFASRSIM 9
           KSF SRS +
Sbjct: 850 KSFTSRSTL 858



>XP_006720675
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 753 KSFSSRS 759



>XP_006720674
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 753 KSFSSRS 759



>XP_006720672
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 841 KSFSSRS 847



>XP_005254605
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 841 KSFSSRS 847



>XP_005254604
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           KSF+SRS
Sbjct: 841 KSFSSRS 847



>XP_005249007
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RS++
Sbjct: 340 KSFSRRSVL 348



>NP_001012458
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSFASRSIM 9
           KSF+ RS++
Sbjct: 340 KSFSRRSVL 348



>NP_001073991
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KSFASRSI 8
            KSF SRS+
Sbjct: 1463 KSFFSRSL 1470



>NP_000099
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSFASRSI 8
           K FASR I
Sbjct: 104 KDFASRGI 111



>NP_001276680
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KSFASRSI 8
          K FASR I
Sbjct: 81 KDFASRGI 88



>NP_001276679
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KSFASRSI 8
          K FASR I
Sbjct: 5  KDFASRGI 12



>NP_001276681
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSFASRSI 8
           K FASR I
Sbjct: 104 KDFASRGI 111



>NP_001136279
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KSFASRSIM 9
          K+F SRS++
Sbjct: 30 KNFVSRSLV 38



>NP_859074
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 447 NFASRSI 453



>NP_071904
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KSFASRS 7
           K FASRS
Sbjct: 731 KQFASRS 737



>NP_001803
          Length = 943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           +SFASRS
Sbjct: 310 QSFASRS 316



>XP_005266561
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KSFASRS 7
           K FASRS
Sbjct: 441 KQFASRS 447



>XP_005266560
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KSFASRS 7
           K FASRS
Sbjct: 731 KQFASRS 737



>XP_005266559
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KSFASRS 7
           K FASRS
Sbjct: 657 KQFASRS 663



>XP_005273535
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 271 NFASRSI 277



>XP_006716393
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 324 NFASRSI 330



>XP_006716392
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 402 NFASRSI 408



>XP_006716391
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 415 NFASRSI 421



>XP_005273534
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFASRSI 8
           +FASRSI
Sbjct: 434 NFASRSI 440



>XP_006714128
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           +SFASRS
Sbjct: 97  QSFASRS 103



>XP_006714127
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSFASRS 7
           +SFASRS
Sbjct: 310 QSFASRS 316



>XP_005248234
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KSFASRSI 8
            KSF SRS+
Sbjct: 1463 KSFFSRSL 1470



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.120    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 270,414
Number of extensions: 512
Number of successful extensions: 46
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)