Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_071423                                                              19     665
XP_005272100                                                           19     665
NP_115803                                                              19     869
NP_061987                                                              18    1482
NP_060894                                                              18    1482
XP_006717209                                                           18    1482
XP_006717208                                                           18    1482
XP_006717207                                                           18    1482
NP_060125                                                              18    1935
XP_005271015                                                           18    1935
XP_005271014                                                           18    1935
XP_005271013                                                           18    1935
NP_060513                                                              17    2528
NP_001171868                                                           17    2528
NP_065960                                                              17    2528
NP_001171866                                                           17    2528
NP_001171867                                                           17    2528
XP_006718668                                                           17    2528
XP_006718666                                                           17    2528
XP_006718664                                                           17    2528
XP_006718663                                                           17    2528
XP_006718660                                                           17    2528
XP_006712716                                                           17    2528
XP_005263777                                                           17    2528
XP_005263776                                                           17    2528
XP_006712715                                                           17    2528
XP_006712714                                                           17    2528
NP_974197                                                              17    4312
NP_974198                                                              17    4312
NP_005707                                                              17    4312
NP_974199                                                              17    4312
NP_974223                                                              17    4312
NP_031374                                                              16    5631
NP_114106                                                              16    5631
XP_005248395                                                           16    5631
XP_005248394                                                           16    5631
XP_006711288                                                           16    5631
XP_006711287                                                           16    5631
NP_056372                                                              16    7355
NP_001034589                                                           16    7355
XP_006710313                                                           16    7355
NP_001018081                                                           15    9605
NP_001274151                                                           15    9605
NP_542415                                                              15    9605
NP_001265485                                                           15    9605
NP_542416                                                              15    9605
NP_542414                                                              15    9605
NP_006255                                                              15    9605
NP_796374                                                              15    9605
NP_006159                                                              15    9605
NP_005843                                                              15    9605
NP_001005273                                                           15    9605
NP_573568                                                              15    9605
XP_005259549                                                           15    9605
XP_006721493                                                           15    9605
XP_006721492                                                           15    9605
XP_006721491                                                           15    9605
XP_006721490                                                           15    9605
XP_006721489                                                           15    9605
XP_006721488                                                           15    9605
XP_005256486                                                           15    9605
XP_005256485                                                           15    9605
XP_006721487                                                           15    9605
XP_006721486                                                           15    9605
XP_005256484                                                           15    9605
XP_005273479                                                           15    9605
XP_005263224                                                           15    9605
XP_006714293                                                           15    9605
NP_001005271                                                           15    9605
NP_001010860                                                           15    9605
>NP_071423
          Length = 686

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSEY LGLT
Sbjct: 218 KSEYFLGLT 226
>XP_005272100
          Length = 658

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSEY LGLT
Sbjct: 218 KSEYFLGLT 226
>NP_115803
          Length = 1156

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSEYS GLT
Sbjct: 365 KSEYSPGLT 373
>NP_061987
          Length = 900

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   EYSLGLT 9
           EYSLGLT
Sbjct: 286 EYSLGLT 292
>NP_060894
          Length = 518

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   EYSLGLT 9
           EYSLGLT
Sbjct: 286 EYSLGLT 292
>XP_006717209
          Length = 812

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   EYSLGLT 9
           EYSLGLT
Sbjct: 286 EYSLGLT 292
>XP_006717208
          Length = 838

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   EYSLGLT 9
           EYSLGLT
Sbjct: 286 EYSLGLT 292
>XP_006717207
          Length = 861

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   EYSLGLT 9
           EYSLGLT
Sbjct: 286 EYSLGLT 292
>NP_060125
          Length = 315

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSE SLGLT
Sbjct: 122 KSEDSLGLT 130
>XP_005271015
          Length = 223

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KSEYSLGLT 9
          KSE SLGLT
Sbjct: 30 KSEDSLGLT 38
>XP_005271014
          Length = 241

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KSEYSLGLT 9
          KSE SLGLT
Sbjct: 48 KSEDSLGLT 56
>XP_005271013
          Length = 249

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSE SLGLT
Sbjct: 122 KSEDSLGLT 130
>NP_060513
          Length = 986

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 261 KAKYSMGIT 269
>NP_001171868
          Length = 505

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>NP_065960
          Length = 733

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>NP_001171866
          Length = 687

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>NP_001171867
          Length = 505

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>XP_006718668
          Length = 840

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 145 KAKYSMGIT 153
>XP_006718666
          Length = 928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 233 KAKYSMGIT 241
>XP_006718664
          Length = 997

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 302 KAKYSMGIT 310
>XP_006718663
          Length = 1001

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 302 KAKYSMGIT 310
>XP_006718660
          Length = 1027

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KSEYSLGLT 9
           K++YS+G+T
Sbjct: 302 KAKYSMGIT 310
>XP_006712716
          Length = 668

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 171 NDYSLGLT 178
>XP_005263777
          Length = 735

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 246 NDYSLGLT 253
>XP_005263776
          Length = 736

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 246 NDYSLGLT 253
>XP_006712715
          Length = 740

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>XP_006712714
          Length = 740

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SEYSLGLT 9
           ++YSLGLT
Sbjct: 243 NDYSLGLT 250
>NP_974197
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSE +LGLT
Sbjct: 138 KSEDALGLT 146
>NP_974198
          Length = 236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KSEYSLGLT 9
          KSE +LGLT
Sbjct: 41 KSEDALGLT 49
>NP_005707
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSE +LGLT
Sbjct: 138 KSEDALGLT 146
>NP_974199
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           KSE +LGLT
Sbjct: 138 KSEDALGLT 146
>NP_974223
          Length = 236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KSEYSLGLT 9
          KSE +LGLT
Sbjct: 41 KSEDALGLT 49
>NP_031374
          Length = 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSEYSLGL 8
           K EY LGL
Sbjct: 327 KKEYMLGL 334
>NP_114106
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SEYSLGLT 9
           S Y+LGLT
Sbjct: 201 SPYTLGLT 208
>XP_005248395
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SEYSLGLT 9
           S Y+LGLT
Sbjct: 201 SPYTLGLT 208
>XP_005248394
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SEYSLGLT 9
           S Y+LGLT
Sbjct: 200 SPYTLGLT 207
>XP_006711288
          Length = 604

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSEYSLGL 8
           K EY LGL
Sbjct: 261 KKEYMLGL 268
>XP_006711287
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSEYSLGL 8
           K EY LGL
Sbjct: 327 KKEYMLGL 334
>NP_056372
          Length = 1954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1369 QSEYSIG 1375
>NP_001034589
          Length = 1215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SEYSLGLT 9
          S Y+LGLT
Sbjct: 25 SGYALGLT 32
>XP_006710313
          Length = 160

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSEYSLGL 8
           + EYS+GL
Sbjct: 127 RGEYSVGL 134
>NP_001018081
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 107 YSLGMT 112
>NP_001274151
          Length = 177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KSEYSLGLT 9
           K  Y+LG+T
Sbjct: 93  KEMYTLGIT 101
>NP_542415
          Length = 2294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 102 YSLGMT 107
>NP_001265485
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KSEYSLGLT 9
           K  Y+LG+T
Sbjct: 93  KEMYTLGIT 101
>NP_542416
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 102 YSLGMT 107
>NP_542414
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 102 YSLGMT 107
>NP_006255
          Length = 2466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 102 YSLGMT 107
>NP_796374
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 183 YSLGMT 188
>NP_006159
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 271 YSLGMT 276
>NP_005843
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>NP_001005273
          Length = 2000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>NP_573568
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           K+E +LGLT
Sbjct: 117 KTEDALGLT 125
>XP_005259549
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSEYSLGLT 9
           K+E +LGLT
Sbjct: 117 KTEDALGLT 125
>XP_006721493
          Length = 2056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1415 QSEYSVG 1421
>XP_006721492
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721491
          Length = 2025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721490
          Length = 2036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1340 QSEYSVG 1346
>XP_006721489
          Length = 2045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721488
          Length = 2056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>XP_005256486
          Length = 2060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_005256485
          Length = 2080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721487
          Length = 2111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1415 QSEYSVG 1421
>XP_006721486
          Length = 2114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_005256484
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_005273479
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 174 YSLGMT 179
>XP_005263224
          Length = 2491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 108 YSLGMT 113
>XP_006714293
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   YSLGLT 9
           YSLG+T
Sbjct: 271 YSLGMT 276
>NP_001005271
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KSEYSLG 7
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>NP_001010860
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KSEYSLG 7
           KS+YS+G
Sbjct: 429 KSKYSVG 435
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.122    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 595,566
Number of extensions: 972
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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