Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     299
NP_001185763                                                           20     299
NP_055459                                                              20     299
XP_006726410                                                           20     299
XP_006711719                                                           20     299
XP_006711718                                                           20     299
XP_006711717                                                           20     299
XP_006711716                                                           20     299
XP_006711715                                                           20     299
XP_006711714                                                           20     299
XP_006711713                                                           20     299
XP_006711712                                                           20     299
XP_006711711                                                           20     299
XP_006711710                                                           20     299
XP_006711709                                                           20     299
XP_005277503                                                           20     299
XP_005273038                                                           20     299
XP_006711708                                                           20     299
XP_005277500                                                           20     299
XP_006711707                                                           20     299
XP_005277499                                                           20     299
XP_006711706                                                           20     299
XP_006711705                                                           20     299
XP_006711164                                                           20     299
XP_006710143                                                           20     299
XP_006710142                                                           20     299
XP_006710141                                                           20     299
NP_001239264                                                           17    4312
NP_005251                                                              17    4312
NP_060151                                                              17    4312
NP_001996                                                              17    4312
NP_001137257                                                           17    4312
NP_001137255                                                           17    4312
NP_001137256                                                           17    4312
NP_005986                                                              17    4312
NP_116255                                                              17    4312
XP_005254784                                                           17    4312
XP_005254783                                                           17    4312
XP_005254939                                                           17    4312
XP_005254938                                                           17    4312
XP_005254937                                                           17    4312
XP_005254934                                                           17    4312
XP_005271926                                                           17    4312
NP_004548                                                              16    5631
NP_001005335                                                           16    5631
NP_001524                                                              16    5631
NP_001012520                                                           16    5631
NP_003743                                                              16    5631
NP_001254503                                                           16    5631
NP_001273407                                                           16    5631
NP_001032897                                                           16    5631
NP_683721                                                              16    5631
NP_001186071                                                           16    5631
NP_001093131                                                           16    5631
XP_005255592                                                           16    5631
XP_006717127                                                           16    5631
NP_075384                                                              16    7355
XP_005256713                                                           16    7355
NP_036424                                                              15    9605
NP_001191344                                                           15    9605
NP_001191343                                                           15    9605
NP_071447                                                              15    9605
NP_001269263                                                           15    9605
NP_001269264                                                           15    9605
NP_001245257                                                           15    9605
NP_777614                                                              15    9605
XP_006722776                                                           15    9605
XP_006713148                                                           15    9605
XP_005271164                                                           15    9605
XP_005271163                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1510 KSEKDQAGL 1518
>NP_001185763
          Length = 2362

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1554 KSEKDQAGL 1562
>NP_055459
          Length = 2346

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1554 KSEKDQAGL 1562
>XP_006726410
          Length = 2087

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1357 KSEKDQAGL 1365
>XP_006711719
          Length = 2302

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1510 KSEKDQAGL 1518
>XP_006711718
          Length = 1436

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KSERDQAGL 9
           KSE+DQAGL
Sbjct: 561 KSEKDQAGL 569
>XP_006711717
          Length = 2385

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1510 KSEKDQAGL 1518
>XP_006711716
          Length = 2411

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1619 KSEKDQAGL 1627
>XP_006711715
          Length = 2428

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1553 KSEKDQAGL 1561
>XP_006711714
          Length = 2429

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1554 KSEKDQAGL 1562
>XP_006711713
          Length = 2432

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1557 KSEKDQAGL 1565
>XP_006711712
          Length = 2473

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_006711711
          Length = 2482

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1607 KSEKDQAGL 1615
>XP_006711710
          Length = 2494

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1619 KSEKDQAGL 1627
>XP_006711709
          Length = 2495

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1620 KSEKDQAGL 1628
>XP_005277503
          Length = 2498

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_005273038
          Length = 2509

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_006711708
          Length = 2512

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_005277500
          Length = 2525

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_006711707
          Length = 2553

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_005277499
          Length = 2561

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_006711706
          Length = 2591

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1716 KSEKDQAGL 1724
>XP_006711705
          Length = 2592

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1717 KSEKDQAGL 1725
>XP_006711164
          Length = 2087

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KSERDQAGL 9
            KSE+DQAGL
Sbjct: 1357 KSEKDQAGL 1365
>XP_006710143
          Length = 562

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KSERDQAGL 9
           KSE+DQAGL
Sbjct: 396 KSEKDQAGL 404
>XP_006710142
          Length = 671

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KSERDQAGL 9
           KSE+DQAGL
Sbjct: 505 KSEKDQAGL 513
>XP_006710141
          Length = 672

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KSERDQAGL 9
           KSE+DQAGL
Sbjct: 506 KSEKDQAGL 514
>NP_001239264
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SERDQAG 8
           SE+DQAG
Sbjct: 813 SEQDQAG 819
>NP_005251
          Length = 454

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ERDQAGL 9
          ERD+AGL
Sbjct: 55 ERDRAGL 61
>NP_060151
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSERDQAGL 9
           +S RDQ+GL
Sbjct: 156 ESTRDQSGL 164
>NP_001996
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>NP_001137257
          Length = 694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>NP_001137255
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>NP_001137256
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>NP_005986
          Length = 385

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSERDQAGL 9
           +++RDQ GL
Sbjct: 354 RADRDQGGL 362
>NP_116255
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SERDQAG 8
           SE+DQAG
Sbjct: 813 SEQDQAG 819
>XP_005254784
          Length = 1303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SERDQAG 8
           SE+DQAG
Sbjct: 813 SEQDQAG 819
>XP_005254783
          Length = 1303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SERDQAG 8
           SE+DQAG
Sbjct: 813 SEQDQAG 819
>XP_005254939
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>XP_005254938
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>XP_005254937
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>XP_005254934
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSERDQAGL 9
          KS+R+ AGL
Sbjct: 39 KSDREYAGL 47
>XP_005271926
          Length = 702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KSERDQAG 8
           K  RDQAG
Sbjct: 406 KKRRDQAG 413
>NP_004548
          Length = 2003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RDQAGL 9
            RDQAGL
Sbjct: 1796 RDQAGL 1801
>NP_001005335
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSERDQAGL 9
           KSER  +GL
Sbjct: 405 KSERSSSGL 413
>NP_001524
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSERDQAGL 9
           KSER  +GL
Sbjct: 538 KSERSSSGL 546
>NP_001012520
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSERDQAGL 9
           KS+RDQ  L
Sbjct: 329 KSQRDQLSL 337
>NP_003743
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 531 KSEQDQA 537
>NP_001254503
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 531 KSEQDQA 537
>NP_001273407
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 521 KSEQDQA 527
>NP_001032897
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 531 KSEQDQA 537
>NP_683721
          Length = 760

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSERDQAGL 9
           ++ER QAGL
Sbjct: 553 EAERGQAGL 561
>NP_001186071
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 531 KSEQDQA 537
>NP_001093131
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 532 KSEQDQA 538
>XP_005255592
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KSERDQA 7
           KSE+DQA
Sbjct: 532 KSEQDQA 538
>XP_006717127
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSERDQAGL 9
           KS+RDQ  L
Sbjct: 329 KSQRDQLSL 337
>NP_075384
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSERDQAG 8
           K +RD+AG
Sbjct: 610 KPQRDEAG 617
>XP_005256713
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SERDQAGL 9
            SER++AG+
Sbjct: 1036 SEREEAGV 1043
>NP_036424
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSERDQAG 8
           K+E +QAG
Sbjct: 425 KAEEEQAG 432
>NP_001191344
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ERDQAG 8
           ERD+AG
Sbjct: 194 ERDEAG 199
>NP_001191343
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ERDQAG 8
           ERD+AG
Sbjct: 268 ERDEAG 273
>NP_071447
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ERDQAG 8
           ERD+AG
Sbjct: 299 ERDEAG 304
>NP_001269263
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KSERDQAG 8
          K+E +QAG
Sbjct: 60 KAEEEQAG 67
>NP_001269264
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSERDQAG 8
           K+E +QAG
Sbjct: 308 KAEEEQAG 315
>NP_001245257
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSERDQAG 8
           K+E +QAG
Sbjct: 441 KAEEEQAG 448
>NP_777614
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SERDQAG 8
            SER++AG
Sbjct: 1036 SEREEAG 1042
>XP_006722776
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSERDQAG 8
           K+E +QAG
Sbjct: 425 KAEEEQAG 432
>XP_006713148
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SERDQAG 8
           +E+DQAG
Sbjct: 669 NEQDQAG 675
>XP_005271164
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ERDQAG 8
           ERD+AG
Sbjct: 194 ERDEAG 199
>XP_005271163
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ERDQAG 8
           ERD+AG
Sbjct: 299 ERDEAG 304
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.121    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 587,326
Number of extensions: 927
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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