Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1482
XP_005262424                                                           18    1482
NP_000202                                                              17    2528
NP_001120963                                                           17    2528
XP_006724064                                                           17    2528
NP_667338                                                              16    5631
NP_001159608                                                           16    5631
NP_079485                                                              16    5631
NP_001258933                                                           16    5631
NP_001269320                                                           16    5631
NP_001258948                                                           16    5631
XP_006717573                                                           16    5631
XP_006713923                                                           16    5631
XP_006713922                                                           16    5631
NP_001243398                                                           15    9605
NP_036462                                                              15    9605
NP_001243397                                                           15    9605
NP_001276968                                                           15    9605
NP_001276969                                                           15    9605
NP_001276994                                                           15    9605
NP_001122401                                                           15    9605
NP_002933                                                              15    9605
XP_005269721                                                           15    9605
XP_006713342                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSATTQILN 9
           KSATTQ LN
Sbjct: 828 KSATTQRLN 836
>XP_005262424
          Length = 2875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSATTQILN 9
           KSATTQ LN
Sbjct: 623 KSATTQRLN 631
>NP_000202
          Length = 769

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSATTQILN 9
           KSATT ++N
Sbjct: 755 KSATTTVMN 763
>NP_001120963
          Length = 769

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSATTQILN 9
           KSATT ++N
Sbjct: 755 KSATTTVMN 763
>XP_006724064
          Length = 700

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSATTQILN 9
           KSATT ++N
Sbjct: 686 KSATTTVMN 694
>NP_667338
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KSATTQIL 8
            KSA TQIL
Sbjct: 1007 KSACTQIL 1014
>NP_001159608
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSATTQIL 8
           KSA TQIL
Sbjct: 927 KSACTQIL 934
>NP_079485
          Length = 836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SATTQIL 8
           SATTQ+L
Sbjct: 744 SATTQVL 750
>NP_001258933
          Length = 813

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SATTQIL 8
           SATTQ+L
Sbjct: 721 SATTQVL 727
>NP_001269320
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SATTQIL 8
           SATTQ+L
Sbjct: 671 SATTQVL 677
>NP_001258948
          Length = 742

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SATTQIL 8
           SATTQ+L
Sbjct: 650 SATTQVL 656
>XP_006717573
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SATTQIL 8
           SATTQ+L
Sbjct: 694 SATTQVL 700
>XP_006713923
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KSATTQIL 8
           KSA TQIL
Sbjct: 927 KSACTQIL 934
>XP_006713922
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KSATTQIL 8
            KSA TQIL
Sbjct: 1007 KSACTQIL 1014
>NP_001243398
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SATTQILN 9
           S TT++LN
Sbjct: 858 SETTEVLN 865
>NP_036462
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SATTQILN 9
            S TT++LN
Sbjct: 1150 SETTEVLN 1157
>NP_001243397
          Length = 1890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SATTQILN 9
           S TT++LN
Sbjct: 967 SETTEVLN 974
>NP_001276968
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ATTQILN 9
            ATTQIL+
Sbjct: 1002 ATTQILH 1008
>NP_001276969
          Length = 1443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ATTQILN 9
            ATTQIL+
Sbjct: 1002 ATTQILH 1008
>NP_001276994
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ATTQILN 9
           ATTQIL+
Sbjct: 405 ATTQILH 411
>NP_001122401
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ATTQILN 9
            ATTQIL+
Sbjct: 1014 ATTQILH 1020
>NP_002933
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ATTQILN 9
            ATTQIL+
Sbjct: 998  ATTQILH 1004
>XP_005269721
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SATTQILN 9
            S TT++LN
Sbjct: 1150 SETTEVLN 1157
>XP_006713342
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ATTQILN 9
            ATTQIL+
Sbjct: 1018 ATTQILH 1024
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.108    0.250 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 242,909
Number of extensions: 142
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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