Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055833                                                              17    2528
NP_001186871                                                           17    2528
XP_006715463                                                           17    2528
XP_006715462                                                           17    2528
XP_006715461                                                           17    2528
XP_006715460                                                           17    2528
XP_006715459                                                           17    2528
XP_006715458                                                           17    2528
XP_006715457                                                           17    2528
XP_006715456                                                           17    2528
NP_062541                                                              17    4312
NP_006268                                                              17    4312
NP_001137531                                                           16    7355
NP_001137530                                                           16    7355
NP_057606                                                              16    7355
NP_001041674                                                           16    7355
NP_055592                                                              16    7355
NP_115655                                                              16    7355
XP_006718920                                                           16    7355
XP_006718919                                                           16    7355
XP_006718918                                                           16    7355
XP_005271639                                                           16    7355
XP_006718917                                                           16    7355
XP_005271637                                                           16    7355
XP_005271638                                                           16    7355
XP_005247886                                                           16    7355
XP_006713849                                                           16    7355
XP_005273417                                                           16    7355
XP_006710019                                                           16    7355
NP_002509                                                              15    9605
XP_005264018                                                           15    9605
XP_005264017                                                           15    9605
XP_005264016                                                           15    9605
XP_005264015                                                           15    9605
XP_005264014                                                           15    9605
XP_005264012                                                           15    9605
XP_005264011                                                           15    9605
XP_005264010                                                           15    9605
>NP_055833
          Length = 2465

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>NP_001186871
          Length = 2476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>XP_006715463
          Length = 2434

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2267 QFQMYR 2272
>XP_006715462
          Length = 2452

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2285 QFQMYR 2290
>XP_006715461
          Length = 2456

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>XP_006715460
          Length = 2465

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>XP_006715459
          Length = 2475

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2308 QFQMYR 2313
>XP_006715458
          Length = 2476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>XP_006715457
          Length = 2485

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>XP_006715456
          Length = 2485

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    QFQMYR 9
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>NP_062541
          Length = 1670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SAQFQMYR 9
            +AQF+MY+
Sbjct: 1456 NAQFKMYK 1463
>NP_006268
          Length = 1697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SAQFQMYR 9
            +AQF+MY+
Sbjct: 1483 NAQFKMYK 1490
>NP_001137531
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_001137530
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_057606
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_001041674
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_055592
          Length = 1524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KSAQFQMYR 9
           + AQF+ YR
Sbjct: 383 EEAQFRFYR 391
>NP_115655
          Length = 1196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   KSAQFQMYR 9
           K   FQ+YR
Sbjct: 388 KPVNFQLYR 396
>XP_006718920
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 209 SAEFQWYK 216
>XP_006718919
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 209 SAEFQWYK 216
>XP_006718918
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 241 SAEFQWYK 248
>XP_005271639
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_006718917
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 241 SAEFQWYK 248
>XP_005271637
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_005271638
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_005247886
          Length = 1127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   KSAQFQMYR 9
           K   FQ+YR
Sbjct: 388 KPVNFQLYR 396
>XP_006713849
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   KSAQFQMYR 9
           K   FQ+YR
Sbjct: 339 KPVNFQLYR 347
>XP_005273417
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KSAQFQMYR 9
           + AQF+ YR
Sbjct: 383 EEAQFRFYR 391
>XP_006710019
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SA+FQ Y+
Sbjct: 448 SAEFQWYK 455
>NP_002509
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 496 SAQFSMFQ 503
>XP_005264018
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 372 SAQFSMFQ 379
>XP_005264017
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 458 SAQFSMFQ 465
>XP_005264016
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 561 SAQFSMFQ 568
>XP_005264015
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 510 SAQFSMFQ 517
>XP_005264014
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 523 SAQFSMFQ 530
>XP_005264012
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 526 SAQFSMFQ 533
>XP_005264011
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 561 SAQFSMFQ 568
>XP_005264010
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SAQFQMYR 9
           SAQF M++
Sbjct: 561 SAQFSMFQ 568
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.125    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 297,130
Number of extensions: 361
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package