Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           19     869
NP_001257437                                                           19     869
NP_006281                                                              19     869
XP_006715618                                                           19     869
XP_005267176                                                           19     869
NP_055898                                                              16    5631
NP_057591                                                              16    5631
XP_005257515                                                           16    5631
XP_005257513                                                           16    5631
XP_006726651                                                           16    7355
>NP_001257436
          Length = 790

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           KRTT EASS
Sbjct: 541 KRTTAEASS 549
>NP_001257437
          Length = 790

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           KRTT EASS
Sbjct: 541 KRTTAEASS 549
>NP_006281
          Length = 790

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           KRTT EASS
Sbjct: 541 KRTTAEASS 549
>XP_006715618
          Length = 577

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           KRTT EASS
Sbjct: 328 KRTTAEASS 336
>XP_005267176
          Length = 790

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           KRTT EASS
Sbjct: 541 KRTTAEASS 549
>NP_055898
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    KRTTVEASS 9
            ++TT+EASS
Sbjct: 1193 EQTTLEASS 1201
>NP_057591
          Length = 1490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    KRTTVEASS 9
            ++TT+EASS
Sbjct: 1193 EQTTLEASS 1201
>XP_005257515
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    KRTTVEASS 9
            ++TT+EASS
Sbjct: 1193 EQTTLEASS 1201
>XP_005257513
          Length = 1489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    KRTTVEASS 9
            ++TT+EASS
Sbjct: 1192 EQTTLEASS 1200
>XP_006726651
          Length = 1456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KRTTVEASS 9
           K+T VEAS+
Sbjct: 180 KKTLVEASA 188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286   0.0948    0.205 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 254,662
Number of extensions: 226
Number of successful extensions: 10
Number of sequences better than 10000.0: 10
Number of HSP's gapped: 10
Number of HSP's successfully gapped: 10
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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