Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_071754                                                              18    1135
NP_001185763                                                           18    1135
NP_001002810                                                           18    1135
NP_055459                                                              18    1135
NP_001182189                                                           18    1135
NP_001002812                                                           18    1135
NP_001182190                                                           18    1135
XP_006711719                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
NP_004953                                                              17    4312
XP_006717825                                                           17    4312
NP_004841                                                              16    5631
NP_056386                                                              16    5631
XP_006715520                                                           16    5631
XP_005246247                                                           16    5631
NP_001093879                                                           16    5631
NP_005742                                                              16    7355
NP_671714                                                              16    7355
NP_008893                                                              16    7355
NP_001171570                                                           16    7355
NP_001007089                                                           16    7355
XP_006715890                                                           16    7355
XP_005250160                                                           16    7355
XP_005250159                                                           16    7355
NP_001074001                                                           16    7355
NP_000811                                                              15    9605
NP_001137417                                                           15    9605
NP_001137418                                                           15    9605
NP_775966                                                              15    9605
NP_001191385                                                           15    9605
NP_055907                                                              15    9605
NP_001001894                                                           15    9605
NP_003307                                                              15    9605
NP_001192                                                              15    9605
NP_001191442                                                           15    9605
NP_057279                                                              15    9605
NP_001271188                                                           15    9605
XP_005261112                                                           15    9605
XP_005261113                                                           15    9605
XP_005261111                                                           15    9605
XP_005261109                                                           15    9605
XP_005261110                                                           15    9605
XP_005261108                                                           15    9605
XP_005261106                                                           15    9605
XP_005261107                                                           15    9605
XP_005261105                                                           15    9605
XP_005261104                                                           15    9605
XP_005261103                                                           15    9605
XP_005261102                                                           15    9605
XP_005255242                                                           15    9605
XP_005255241                                                           15    9605
XP_005255240                                                           15    9605
XP_005255239                                                           15    9605
XP_006714354                                                           15    9605
NP_066986                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>NP_071754
          Length = 310

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 183 KRNIELKVE 191
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>NP_001002810
          Length = 173

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>NP_001182189
          Length = 141

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 14 KRNIELKVE 22
>NP_001002812
          Length = 969

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>NP_001182190
          Length = 176

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 49 KRNIELKVE 57
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 46 KRNIELKVE 54
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          KRNI LKVE
Sbjct: 49 KRNIELKVE 57
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRNIVLKVE 9
           KRNI LKVE
Sbjct: 112 KRNIELKVE 120
>NP_004953
          Length = 478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           RN+VLKV
Sbjct: 460 RNVVLKV 466
>XP_006717825
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           RN+VLKV
Sbjct: 459 RNVVLKV 465
>NP_004841
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNIVLKVE 9
           RN+ LK+E
Sbjct: 790 RNLTLKIE 797
>NP_056386
          Length = 1112

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RNI+LK++
Sbjct: 1072 RNIILKLQ 1079
>XP_006715520
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RNI+LK++
Sbjct: 1016 RNIILKLQ 1023
>XP_005246247
          Length = 1417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNIVLKVE 9
           RN+ LK+E
Sbjct: 790 RNLTLKIE 797
>NP_001093879
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RNI+LK++
Sbjct: 1065 RNIILKLQ 1072
>NP_005742
          Length = 3907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RN+V+K+E
Sbjct: 3610 RNMVMKLE 3617
>NP_671714
          Length = 3899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RN+V+K+E
Sbjct: 3602 RNMVMKLE 3609
>NP_008893
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N++LK+E
Sbjct: 72 KPNLILKLE 80
>NP_001171570
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N++LK+E
Sbjct: 72 KPNLILKLE 80
>NP_001007089
          Length = 620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N++LK+E
Sbjct: 53 KPNLILKLE 61
>XP_006715890
          Length = 3860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RN+V+K+E
Sbjct: 3563 RNMVMKLE 3570
>XP_005250160
          Length = 3939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RN+V+K+E
Sbjct: 3642 RNMVMKLE 3649
>XP_005250159
          Length = 3952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    RNIVLKVE 9
            RN+V+K+E
Sbjct: 3655 RNMVMKLE 3662
>NP_001074001
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RNIVLKVE 9
          +NIVLK E
Sbjct: 82 KNIVLKFE 89
>NP_000811
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           RN+V+KV
Sbjct: 389 RNLVIKV 395
>NP_001137417
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           RN+V+KV
Sbjct: 116 RNLVIKV 122
>NP_001137418
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RNIVLKV 8
          RN+V+KV
Sbjct: 90 RNLVIKV 96
>NP_775966
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KRNIVLK 7
          K+NI+LK
Sbjct: 7  KQNIILK 13
>NP_001191385
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N+++K+E
Sbjct: 53 KPNVIIKLE 61
>NP_055907
          Length = 3661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIVLK 7
            +RN+VLK
Sbjct: 3285 RRNLVLK 3291
>NP_001001894
          Length = 2025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1184 KKNIKTKVE 1192
>NP_003307
          Length = 2025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1184 KKNIKTKVE 1192
>NP_001192
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           +N+VLKV
Sbjct: 454 KNVVLKV 460
>NP_001191442
          Length = 113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N+++K+E
Sbjct: 53 KPNVIIKLE 61
>NP_057279
          Length = 1780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KRNIVLKVE 9
            K +I+LK+E
Sbjct: 1150 KESIILKLE 1158
>NP_001271188
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KRNIVLKVE 9
            K +I+LK+E
Sbjct: 1190 KESIILKLE 1198
>XP_005261112
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KRNIVLKVE 9
           K+NI  KVE
Sbjct: 892 KKNIKTKVE 900
>XP_005261113
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KRNIVLKVE 9
           K+NI  KVE
Sbjct: 892 KKNIKTKVE 900
>XP_005261111
          Length = 2043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1202 KKNIKTKVE 1210
>XP_005261109
          Length = 2043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1202 KKNIKTKVE 1210
>XP_005261110
          Length = 2043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1202 KKNIKTKVE 1210
>XP_005261108
          Length = 2047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1206 KKNIKTKVE 1214
>XP_005261106
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1218 KKNIKTKVE 1226
>XP_005261107
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1218 KKNIKTKVE 1226
>XP_005261105
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1218 KKNIKTKVE 1226
>XP_005261104
          Length = 2063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1222 KKNIKTKVE 1230
>XP_005261103
          Length = 2065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1224 KKNIKTKVE 1232
>XP_005261102
          Length = 2081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KRNIVLKVE 9
            K+NI  KVE
Sbjct: 1240 KKNIKTKVE 1248
>XP_005255242
          Length = 3609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIVLK 7
            +RN+VLK
Sbjct: 3233 RRNLVLK 3239
>XP_005255241
          Length = 3637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIVLK 7
            +RN+VLK
Sbjct: 3261 RRNLVLK 3267
>XP_005255240
          Length = 3663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIVLK 7
            +RN+VLK
Sbjct: 3287 RRNLVLK 3293
>XP_005255239
          Length = 3689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIVLK 7
            +RN+VLK
Sbjct: 3313 RRNLVLK 3319
>XP_006714354
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RNIVLKV 8
           +N+VLKV
Sbjct: 421 KNVVLKV 427
>NP_066986
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KRNIVLKVE 9
          K N+++K+E
Sbjct: 53 KPNVIIKLE 61
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.139    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 360,701
Number of extensions: 780
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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