Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_071754                                                              19     665
NP_001185763                                                           19     665
NP_001002810                                                           19     665
NP_055459                                                              19     665
NP_001182189                                                           19     665
NP_001002812                                                           19     665
NP_001182190                                                           19     665
XP_006711719                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
NP_060719                                                              17    3301
NP_001258968                                                           17    3301
NP_001011649                                                           17    3301
XP_006717248                                                           17    3301
XP_006717247                                                           17    3301
XP_006717246                                                           17    3301
XP_006717245                                                           17    3301
XP_006717244                                                           17    3301
XP_006717243                                                           17    3301
XP_006717242                                                           17    3301
NP_002408                                                              16    7355
NP_001139438                                                           16    7355
NP_689810                                                              16    7355
NP_005723                                                              16    7355
XP_006720481                                                           16    7355
XP_006720480                                                           16    7355
XP_005254266                                                           16    7355
XP_006720479                                                           16    7355
XP_005254265                                                           16    7355
XP_006717927                                                           16    7355
XP_006716433                                                           16    7355
XP_005273633                                                           16    7355
XP_006716432                                                           16    7355
XP_005273632                                                           16    7355
NP_112561                                                              16    7355
NP_689879                                                              15    9605
NP_001182740                                                           15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_060103                                                              15    9605
NP_001185736                                                           15    9605
NP_004679                                                              15    9605
XP_006724177                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_005246998                                                           15    9605
XP_006711815                                                           15    9605
NP_443175                                                              15    9605
NP_060179                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>NP_071754
          Length = 310

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 183 KRNIELKV 190
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>NP_001002810
          Length = 173

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>NP_001182189
          Length = 141

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 14 KRNIELKV 21
>NP_001002812
          Length = 969

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>NP_001182190
          Length = 176

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 49 KRNIELKV 56
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 46 KRNIELKV 53
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  KRNIELKV 8
          KRNIELKV
Sbjct: 49 KRNIELKV 56
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KRNIELKV 8
           KRNIELKV
Sbjct: 112 KRNIELKV 119
>NP_060719
          Length = 1893

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>NP_001258968
          Length = 1663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>NP_001011649
          Length = 1814

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717248
          Length = 1664

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717247
          Length = 1670

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717246
          Length = 1820

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717245
          Length = 1861

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717244
          Length = 1867

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 101 KTNIELKV 108
>XP_006717243
          Length = 1889

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KRNIELKV 8
          K NIELKV
Sbjct: 91 KTNIELKV 98
>XP_006717242
          Length = 1898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KRNIELKV 8
           K NIELKV
Sbjct: 100 KTNIELKV 107
>NP_002408
          Length = 3256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KRNIELK 7
           K NIELK
Sbjct: 933 KENIELK 939
>NP_001139438
          Length = 2896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KRNIELK 7
           K NIELK
Sbjct: 573 KENIELK 579
>NP_689810
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>NP_005723
          Length = 1312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KRNIELKVV 9
            KRN ELK V
Sbjct: 1026 KRNEELKEV 1034
>XP_006720481
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>XP_006720480
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>XP_005254266
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>XP_006720479
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>XP_005254265
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRNIEL 6
           KRNIEL
Sbjct: 256 KRNIEL 261
>XP_006717927
          Length = 2406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  KRNIELK 7
          K NIELK
Sbjct: 83 KENIELK 89
>XP_006716433
          Length = 3069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIELK 7
            KRN+E+K
Sbjct: 1574 KRNLEVK 1580
>XP_005273633
          Length = 3069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIELK 7
            KRN+E+K
Sbjct: 1574 KRNLEVK 1580
>XP_006716432
          Length = 3172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIELK 7
            KRN+E+K
Sbjct: 1677 KRNLEVK 1683
>XP_005273632
          Length = 3172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIELK 7
            KRN+E+K
Sbjct: 1677 KRNLEVK 1683
>NP_112561
          Length = 2789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KRNIELK 7
            KRN+E+K
Sbjct: 1294 KRNLEVK 1300
>NP_689879
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RNIELKVV 9
           +NIE+K+V
Sbjct: 179 QNIEIKLV 186
>NP_001182740
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RNIELKVV 9
           +NIE+K+V
Sbjct: 117 QNIEIKLV 124
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RNIELKVV 9
            ++IELKVV
Sbjct: 2714 QSIELKVV 2721
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RNIELKVV 9
            ++IELKVV
Sbjct: 2739 QSIELKVV 2746
>NP_060103
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNIELKVV 9
           +N+ELK V
Sbjct: 212 KNVELKFV 219
>NP_001185736
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KRNIELKVV 9
           KR++EL ++
Sbjct: 146 KRSLELSII 154
>NP_004679
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KRNIELK 7
          K+NI+LK
Sbjct: 35 KKNIQLK 41
>XP_006724177
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KRNIELKVV 9
          +RN+ +KV+
Sbjct: 6  ERNLSIKVI 14
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RNIELKVV 9
            ++IELKVV
Sbjct: 2739 QSIELKVV 2746
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RNIELKVV 9
            ++IELKVV
Sbjct: 2739 QSIELKVV 2746
>XP_005246998
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KRNIELK 7
          K+NI+LK
Sbjct: 35 KKNIQLK 41
>XP_006711815
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RNIELKVV 9
           +NIE+K+V
Sbjct: 179 QNIEIKLV 186
>NP_443175
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNIELKVV 9
           +N+ELK V
Sbjct: 198 KNVELKFV 205
>NP_060179
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNIELKVV 9
           +N+ELK V
Sbjct: 163 KNVELKFV 170
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.139    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 406,869
Number of extensions: 910
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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