Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     299
XP_006716142                                                           20     299
XP_005250088                                                           20     299
XP_006716141                                                           20     299
XP_006716140                                                           20     299
XP_005250084                                                           20     299
XP_005250083                                                           20     299
XP_005250082                                                           20     299
NP_001265488                                                           17    2528
XP_006715693                                                           17    2528
XP_006715692                                                           17    2528
XP_005266998                                                           17    3301
NP_689908                                                              17    4312
XP_005262452                                                           17    4312
NP_001099007                                                           16    5631
XP_006712793                                                           16    5631
NP_997244                                                              16    7355
NP_003092                                                              16    7355
NP_001239441                                                           16    7355
NP_001171992                                                           16    7355
NP_009062                                                              16    7355
NP_001239440                                                           16    7355
NP_075048                                                              16    7355
XP_005262528                                                           16    7355
XP_005262527                                                           16    7355
XP_005262526                                                           16    7355
XP_006710345                                                           16    7355
XP_006710344                                                           16    7355
XP_006710343                                                           16    7355
XP_006710342                                                           16    7355
NP_006305                                                              16    7355
NP_665739                                                              15    9605
NP_997054                                                              15    9605
NP_001181866                                                           15    9605
NP_055915                                                              15    9605
NP_001181867                                                           15    9605
NP_005567                                                              15    9605
NP_000410                                                              15    9605
NP_055392                                                              15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_002603                                                              15    9605
NP_001005850                                                           15    9605
NP_055077                                                              15    9605
XP_005261530                                                           15    9605
XP_006724279                                                           15    9605
XP_006724278                                                           15    9605
XP_006724277                                                           15    9605
XP_006724276                                                           15    9605
XP_006724275                                                           15    9605
XP_005261529                                                           15    9605
XP_006724274                                                           15    9605
XP_006724273                                                           15    9605
XP_005261528                                                           15    9605
XP_005261527                                                           15    9605
XP_005259440                                                           15    9605
XP_005259439                                                           15    9605
XP_006722935                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_006711300                                                           15    9605
XP_005245063                                                           15    9605
XP_005245062                                                           15    9605
XP_005245061                                                           15    9605
XP_005245060                                                           15    9605
XP_005245057                                                           15    9605
XP_005245058                                                           15    9605
XP_005245056                                                           15    9605
NP_067092                                                              15    9605
>NP_733751
          Length = 4911

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4720 KRFVLRPHT 4728
>XP_006716142
          Length = 4927

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4736 KRFVLRPHT 4744
>XP_005250088
          Length = 4928

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4737 KRFVLRPHT 4745
>XP_006716141
          Length = 4959

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4768 KRFVLRPHT 4776
>XP_006716140
          Length = 4982

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4791 KRFVLRPHT 4799
>XP_005250084
          Length = 4982

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4791 KRFVLRPHT 4799
>XP_005250083
          Length = 4982

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4791 KRFVLRPHT 4799
>XP_005250082
          Length = 4983

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KRFVLRSHT 9
            KRFVLR HT
Sbjct: 4792 KRFVLRPHT 4800
>NP_001265488
          Length = 1004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KRFVLRSH 8
           KRFV +SH
Sbjct: 408 KRFVYKSH 415
>XP_006715693
          Length = 1004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KRFVLRSH 8
           KRFV +SH
Sbjct: 408 KRFVYKSH 415
>XP_006715692
          Length = 1004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KRFVLRSH 8
           KRFV +SH
Sbjct: 408 KRFVYKSH 415
>XP_005266998
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           +R VLR+HT
Sbjct: 653 ERHVLRAHT 661
>NP_689908
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF  RSH
Sbjct: 386 KRFTRRSH 393
>XP_005262452
          Length = 277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF  RSH
Sbjct: 145 KRFTRRSH 152
>NP_001099007
          Length = 1687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RFVLRSH 8
            RF+LR+H
Sbjct: 1577 RFLLRTH 1583
>XP_006712793
          Length = 1887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RFVLRSH 8
            RF+LR+H
Sbjct: 1777 RFLLRTH 1783
>NP_997244
          Length = 3169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KRFVLRSH 8
           +RFV+R H
Sbjct: 687 QRFVIRIH 694
>NP_003092
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RFVLRSHT 9
           RFV+++H+
Sbjct: 262 RFVMKAHS 269
>NP_001239441
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RFVLRSHT 9
           RFV+++H+
Sbjct: 197 RFVMKAHS 204
>NP_001171992
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF+  SH
Sbjct: 361 KRFIQNSH 368
>NP_009062
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF+  SH
Sbjct: 456 KRFIQNSH 463
>NP_001239440
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RFVLRSHT 9
           RFV+++H+
Sbjct: 204 RFVMKAHS 211
>NP_075048
          Length = 1088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RFVLRSHT 9
           +F+L++HT
Sbjct: 636 KFMLKNHT 643
>XP_005262528
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF+  SH
Sbjct: 249 KRFIQNSH 256
>XP_005262527
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF+  SH
Sbjct: 288 KRFIQNSH 295
>XP_005262526
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF+  SH
Sbjct: 456 KRFIQNSH 463
>XP_006710345
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FVLRSHT 9
           FVL+ HT
Sbjct: 164 FVLKGHT 170
>XP_006710344
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FVLRSHT 9
           FVL+ HT
Sbjct: 429 FVLKGHT 435
>XP_006710343
          Length = 754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FVLRSHT 9
           FVL+ HT
Sbjct: 463 FVLKGHT 469
>XP_006710342
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FVLRSHT 9
           FVL+ HT
Sbjct: 470 FVLKGHT 476
>NP_006305
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FVLRSHT 9
           FVL+ HT
Sbjct: 422 FVLKGHT 428
>NP_665739
          Length = 1315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   RFVLRSH 8
           RF+LR H
Sbjct: 979 RFMLRHH 985
>NP_997054
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1021 RFMLRHH 1027
>NP_001181866
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1065 RFMLRHH 1071
>NP_055915
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1074 RFMLRHH 1080
>NP_001181867
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1012 RFMLRHH 1018
>NP_005567
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   KRFVLRSHT 9
           KR+   SHT
Sbjct: 493 KRYACTSHT 501
>NP_000410
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RFVLRSH 8
           +FVL+SH
Sbjct: 952 QFVLQSH 958
>NP_055392
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 470 KQFVERAHS 478
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    FVLRSH 8
            F++RSH
Sbjct: 2822 FIMRSH 2827
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    FVLRSH 8
            F++RSH
Sbjct: 2847 FIMRSH 2852
>NP_002603
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RFVLRS 7
          RFVLRS
Sbjct: 5  RFVLRS 10
>NP_001005850
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF  RSH
Sbjct: 369 KRFSNRSH 376
>NP_055077
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KRFVLRS 7
           +RF+LRS
Sbjct: 377 QRFILRS 383
>XP_005261530
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KRFVLRSHT 9
          K+FV R+H+
Sbjct: 65 KQFVERAHS 73
>XP_006724279
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KRFVLRSHT 9
          K+FV R+H+
Sbjct: 83 KQFVERAHS 91
>XP_006724278
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 507 KQFVERAHS 515
>XP_006724277
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 507 KQFVERAHS 515
>XP_006724276
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 470 KQFVERAHS 478
>XP_006724275
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 507 KQFVERAHS 515
>XP_005261529
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 507 KQFVERAHS 515
>XP_006724274
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 470 KQFVERAHS 478
>XP_006724273
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 470 KQFVERAHS 478
>XP_005261528
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 470 KQFVERAHS 478
>XP_005261527
          Length = 1226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRFVLRSHT 9
           K+FV R+H+
Sbjct: 507 KQFVERAHS 515
>XP_005259440
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF  RSH
Sbjct: 369 KRFSNRSH 376
>XP_005259439
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           KRF  RSH
Sbjct: 369 KRFSNRSH 376
>XP_006722935
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           K F+L SH
Sbjct: 419 KSFILSSH 426
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    FVLRSH 8
            F++RSH
Sbjct: 2847 FIMRSH 2852
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    FVLRSH 8
            F++RSH
Sbjct: 2847 FIMRSH 2852
>XP_006711300
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1012 RFMLRHH 1018
>XP_005245063
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1021 RFMLRHH 1027
>XP_005245062
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1021 RFMLRHH 1027
>XP_005245061
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1021 RFMLRHH 1027
>XP_005245060
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1065 RFMLRHH 1071
>XP_005245057
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1074 RFMLRHH 1080
>XP_005245058
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1074 RFMLRHH 1080
>XP_005245056
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RFVLRSH 8
            RF+LR H
Sbjct: 1074 RFMLRHH 1080
>NP_067092
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRFVLRSH 8
           K F+L SH
Sbjct: 483 KSFILSSH 490
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.139    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 548,289
Number of extensions: 969
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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