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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              19     665
XP_005269721                                                           19     665
NP_008952                                                              17    3301
NP_001034463                                                           17    3301
NP_443198                                                              17    3301
NP_001123362                                                           16    5631
NP_001275938                                                           16    7355
NP_001275990                                                           16    7355
NP_001275987                                                           16    7355
NP_112168                                                              16    7355
NP_060512                                                              16    7355
XP_006722030                                                           16    7355
XP_005258052                                                           16    7355
XP_006718343                                                           16    7355
XP_006718342                                                           16    7355
XP_006718341                                                           16    7355
XP_006713324                                                           16    7355
NP_001171886                                                           15    9605
NP_115513                                                              15    9605
NP_001171887                                                           15    9605
NP_036585                                                              15    9605
NP_001273424                                                           15    9605
NP_006181                                                              15    9605
NP_062546                                                              15    9605
NP_060009                                                              15    9605
NP_001182719                                                           15    9605
XP_006721125                                                           15    9605
XP_006720675                                                           15    9605
XP_006720674                                                           15    9605
XP_006720673                                                           15    9605
XP_006720672                                                           15    9605
XP_005254605                                                           15    9605
XP_005254604                                                           15    9605
XP_006715986                                                           15    9605
XP_006713407                                                           15    9605
XP_006713406                                                           15    9605
XP_006713405                                                           15    9605
XP_006713404                                                           15    9605
XP_006712618                                                           15    9605

>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRDITSRFI 9
           KRDI SRFI
Sbjct: 590 KRDIRSRFI 598



>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRDITSRFI 9
           KRDI SRFI
Sbjct: 590 KRDIRSRFI 598



>NP_008952
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RDITSRF 8
          RDIT+RF
Sbjct: 83 RDITARF 89



>NP_001034463
          Length = 534

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DITSRFI 9
           DITSRF+
Sbjct: 317 DITSRFL 323



>NP_443198
          Length = 928

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  KRDITSRFI 9
          +RD+TS+F+
Sbjct: 51 QRDLTSQFL 59



>NP_001123362
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RDITSRFI 9
           ++ITSRF+
Sbjct: 251 QEITSRFV 258



>NP_001275938
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRDITS 6
           KRDITS
Sbjct: 128 KRDITS 133



>NP_001275990
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 67 RDITSR 72



>NP_001275987
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 26 RDITSR 31



>NP_112168
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 67 RDITSR 72



>NP_060512
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRDITS 6
           KRDITS
Sbjct: 128 KRDITS 133



>XP_006722030
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRDITS 6
           KRDITS
Sbjct: 128 KRDITS 133



>XP_005258052
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRDITS 6
           KRDITS
Sbjct: 128 KRDITS 133



>XP_006718343
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 26 RDITSR 31



>XP_006718342
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 67 RDITSR 72



>XP_006718341
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RDITSR 7
          RDITSR
Sbjct: 26 RDITSR 31



>XP_006713324
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    KRDITSRF 8
            KRD+  RF
Sbjct: 1257 KRDVKKRF 1264



>NP_001171886
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DITSRFI 9
          DIT RF+
Sbjct: 46 DITRRFV 52



>NP_115513
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 168 DITRRFV 174



>NP_001171887
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DITSRFI 9
          DIT RF+
Sbjct: 46 DITRRFV 52



>NP_036585
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 382 DITGRFL 388



>NP_001273424
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 630 DLTSRF 635



>NP_006181
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRDITSRF 8
           KRD+  RF
Sbjct: 319 KRDLLERF 326



>NP_062546
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 623 DLTSRF 628



>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    KRDITSRF 8
            + DIT RF
Sbjct: 2196 RNDITGRF 2203



>NP_001182719
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KRDITS 6
           KRD+TS
Sbjct: 146 KRDVTS 151



>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    KRDITSRF 8
            + DIT RF
Sbjct: 2150 RNDITGRF 2157



>XP_006720675
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 535 DLTSRF 540



>XP_006720674
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 535 DLTSRF 540



>XP_006720673
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 623 DLTSRF 628



>XP_006720672
          Length = 1053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 623 DLTSRF 628



>XP_005254605
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 623 DLTSRF 628



>XP_005254604
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DITSRF 8
           D+TSRF
Sbjct: 623 DLTSRF 628



>XP_006715986
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 349 DITGRFL 355



>XP_006713407
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 168 DITRRFV 174



>XP_006713406
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 168 DITRRFV 174



>XP_006713405
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 168 DITRRFV 174



>XP_006713404
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DITSRFI 9
           DIT RF+
Sbjct: 168 DITRRFV 174



>XP_006712618
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KRDITSRF 8
           KRD+  RF
Sbjct: 319 KRDLLERF 326



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.147    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,467
Number of extensions: 529
Number of successful extensions: 39
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)