Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           20     509
NP_001138390                                                           20     509
NP_001138386                                                           20     509
NP_001138387                                                           20     509
NP_000132                                                              20     509
NP_075259                                                              20     509
NP_001138388                                                           20     509
NP_001138391                                                           20     509
NP_001138385                                                           20     509
NP_075418                                                              20     509
XP_006717776                                                           20     509
XP_006717775                                                           20     509
XP_006717774                                                           20     509
XP_006717773                                                           20     509
XP_006717772                                                           20     509
XP_006717771                                                           20     509
NP_001186017                                                           17    3301
NP_001186015                                                           17    3301
NP_001186016                                                           17    3301
NP_150278                                                              17    3301
NP_001002006                                                           17    3301
NP_001186032                                                           17    3301
NP_001186033                                                           17    3301
NP_056370                                                              17    4312
NP_001026794                                                           17    4312
XP_005249051                                                           17    4312
NP_001157570                                                           16    5631
NP_004376                                                              16    5631
NP_003646                                                              16    5631
NP_056477                                                              16    5631
NP_001017408                                                           16    5631
NP_065132                                                              16    5631
NP_001265874                                                           16    5631
NP_001248385                                                           16    5631
NP_060962                                                              16    5631
NP_002339                                                              16    5631
NP_001713                                                              16    5631
NP_001028839                                                           16    5631
NP_001248386                                                           16    5631
XP_006716431                                                           16    5631
XP_006712050                                                           16    5631
XP_005264311                                                           16    5631
XP_006712049                                                           16    5631
XP_006711388                                                           16    5631
XP_006711387                                                           16    5631
XP_006711386                                                           16    5631
XP_006711385                                                           16    5631
XP_006711384                                                           16    5631
XP_006711383                                                           16    5631
XP_005245221                                                           16    5631
NP_115915                                                              16    7355
NP_001243755                                                           16    7355
NP_057535                                                              16    7355
NP_001137534                                                           16    7355
NP_001137533                                                           16    7355
NP_001030024                                                           15    9605
NP_071420                                                              15    9605
NP_031377                                                              15    9605
NP_775836                                                              15    9605
XP_005268053                                                           15    9605
XP_005268052                                                           15    9605
XP_005250200                                                           15    9605
XP_006715831                                                           15    9605
XP_005249890                                                           15    9605
XP_006715830                                                           15    9605
XP_005249889                                                           15    9605
XP_005249888                                                           15    9605
XP_005249887                                                           15    9605
XP_006715829                                                           15    9605
XP_005249716                                                           15    9605
XP_005249717                                                           15    9605
XP_006715732                                                           15    9605
XP_005262913                                                           15    9605
NP_001132928                                                           15    9605
NP_001093167                                                           15    9605
>NP_001138389
          Length = 705

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 391 KPKEAVTV 398
>NP_001138390
          Length = 704

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 390 KPKEAVTV 397
>NP_001138386
          Length = 709

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 395 KPKEAVTV 402
>NP_001138387
          Length = 707

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 418 KPKEAVTV 425
>NP_000132
          Length = 821

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 507 KPKEAVTV 514
>NP_075259
          Length = 822

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 508 KPKEAVTV 515
>NP_001138388
          Length = 706

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 392 KPKEAVTV 399
>NP_001138391
          Length = 680

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 419 KPKEAVTV 426
>NP_001138385
          Length = 769

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 508 KPKEAVTV 515
>NP_075418
          Length = 732

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 418 KPKEAVTV 425
>XP_006717776
          Length = 806

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 526 KPKEAVTV 533
>XP_006717775
          Length = 726

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 412 KPKEAVTV 419
>XP_006717774
          Length = 752

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 438 KPKEAVTV 445
>XP_006717773
          Length = 807

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 527 KPKEAVTV 534
>XP_006717772
          Length = 838

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 524 KPKEAVTV 531
>XP_006717771
          Length = 839

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   KPKEAVTV 8
           KPKEAVTV
Sbjct: 525 KPKEAVTV 532
>NP_001186017
          Length = 612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 305 KPKNAITI 312
>NP_001186015
          Length = 593

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 286 KPKNAITI 293
>NP_001186016
          Length = 627

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 320 KPKNAITI 327
>NP_150278
          Length = 550

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 243 KPKNAITI 250
>NP_001002006
          Length = 610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 303 KPKNAITI 310
>NP_001186032
          Length = 650

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 245 KPKNAITI 252
>NP_001186033
          Length = 602

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KPK A+T+
Sbjct: 303 KPKNAITI 310
>NP_056370
          Length = 1013

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KPKEAVTVV 9
           KP  A+TV+
Sbjct: 585 KPSSAITVI 593
>NP_001026794
          Length = 1061

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KPKEAVTVV 9
           KP  A+TV+
Sbjct: 585 KPSSAITVI 593
>XP_005249051
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KPKEAVTVV 9
           KP  A+TV+
Sbjct: 585 KPSSAITVI 593
>NP_001157570
          Length = 1642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    PKEAVT 7
            PKEAVT
Sbjct: 1056 PKEAVT 1061
>NP_004376
          Length = 3396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    PKEAVT 7
            PKEAVT
Sbjct: 1056 PKEAVT 1061
>NP_003646
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PKEAVT 7
           PKEAVT
Sbjct: 237 PKEAVT 242
>NP_056477
          Length = 1749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KPKEAV 6
            KPKEAV
Sbjct: 1170 KPKEAV 1175
>NP_001017408
          Length = 454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KPKEAVTVV 9
           K KEAVT++
Sbjct: 340 KHKEAVTIL 348
>NP_065132
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KPKEAVTVV 9
           K KEAVT++
Sbjct: 348 KHKEAVTIL 356
>NP_001265874
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KPKEAV 6
           KPKEAV
Sbjct: 224 KPKEAV 229
>NP_001248385
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>NP_060962
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KPKEAV 6
           KPKEAV
Sbjct: 213 KPKEAV 218
>NP_002339
          Length = 655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>NP_001713
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KPKEAVTV 8
          +PKE VTV
Sbjct: 70 EPKEEVTV 77
>NP_001028839
          Length = 193

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>NP_001248386
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006716431
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KPKEAV 6
           KPKEAV
Sbjct: 213 KPKEAV 218
>XP_006712050
          Length = 1716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KPKEAV 6
            KPKEAV
Sbjct: 1170 KPKEAV 1175
>XP_005264311
          Length = 1727

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KPKEAV 6
            KPKEAV
Sbjct: 1148 KPKEAV 1153
>XP_006712049
          Length = 1728

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KPKEAV 6
            KPKEAV
Sbjct: 1149 KPKEAV 1154
>XP_006711388
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006711387
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006711386
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006711385
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006711384
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_006711383
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>XP_005245221
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KPKEAVTVV 9
          +PKE VT++
Sbjct: 91 RPKENVTIM 99
>NP_115915
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KPKEAVTV 8
          KP+ AVT+
Sbjct: 47 KPQNAVTI 54
>NP_001243755
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KPKEAVTVV 9
           +PK AVT++
Sbjct: 402 RPKVAVTMI 410
>NP_057535
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+E +TV
Sbjct: 501 KPEEEITV 508
>NP_001137534
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+E +TV
Sbjct: 501 KPEEEITV 508
>NP_001137533
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+E +TV
Sbjct: 501 KPEEEITV 508
>NP_001030024
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+EAV V
Sbjct: 108 KPQEAVFV 115
>NP_071420
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+EAV V
Sbjct: 108 KPQEAVFV 115
>NP_031377
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           +PKEA+ +
Sbjct: 667 QPKEAIVI 674
>NP_775836
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 850 PKEDVTV 856
>XP_005268053
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+EAV V
Sbjct: 108 KPQEAVFV 115
>XP_005268052
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           KP+EAV V
Sbjct: 108 KPQEAVFV 115
>XP_005250200
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KPKEAVTVV 9
          KP E VT++
Sbjct: 4  KPTEPVTIL 12
>XP_006715831
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 546 PKEDVTV 552
>XP_005249890
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 642 PKEDVTV 648
>XP_006715830
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 737 PKEDVTV 743
>XP_005249889
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 790 PKEDVTV 796
>XP_005249888
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 807 PKEDVTV 813
>XP_005249887
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 850 PKEDVTV 856
>XP_006715829
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 855 PKEDVTV 861
>XP_005249716
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 850 PKEDVTV 856
>XP_005249717
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 572 PKEDVTV 578
>XP_006715732
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 626 PKEDVTV 632
>XP_005262913
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KPKEAVTV 8
           +PKEA+ +
Sbjct: 632 QPKEAIVI 639
>NP_001132928
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KPKEAVTVV 9
          KP E VT++
Sbjct: 4  KPTEPVTIL 12
>NP_001093167
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PKEAVTV 8
           PKE VTV
Sbjct: 850 PKEDVTV 856
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.121    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 563,765
Number of extensions: 698
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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