Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_001245240                                                           17    3301
NP_037484                                                              17    4312
NP_001074445                                                           17    4312
NP_001121190                                                           17    4312
NP_001121189                                                           17    4312
NP_008966                                                              17    4312
XP_005267010                                                           17    4312
NP_003356                                                              16    5631
NP_937762                                                              16    7355
NP_000218                                                              16    7355
NP_055616                                                              16    7355
XP_005273329                                                           16    7355
NP_001273596                                                           15    9605
NP_001273595                                                           15    9605
NP_001273594                                                           15    9605
NP_598397                                                              15    9605
NP_004728                                                              15    9605
NP_001129406                                                           15    9605
NP_001129407                                                           15    9605
NP_006466                                                              15    9605
NP_001129408                                                           15    9605
NP_001265520                                                           15    9605
NP_001265519                                                           15    9605
NP_919433                                                              15    9605
NP_006850                                                              15    9605
NP_002261                                                              15    9605
NP_694858                                                              15    9605
NP_001243481                                                           15    9605
NP_001129668                                                           15    9605
NP_078884                                                              15    9605
NP_001230050                                                           15    9605
NP_001104779                                                           15    9605
NP_006193                                                              15    9605
NP_001104778                                                           15    9605
NP_001104777                                                           15    9605
NP_001258029                                                           15    9605
NP_001129505                                                           15    9605
NP_001129667                                                           15    9605
NP_038461                                                              15    9605
NP_055096                                                              15    9605
NP_510965                                                              15    9605
NP_001032416                                                           15    9605
NP_002591                                                              15    9605
NP_001258028                                                           15    9605
NP_001258026                                                           15    9605
NP_001032418                                                           15    9605
NP_078895                                                              15    9605
NP_001258025                                                           15    9605
NP_001258027                                                           15    9605
XP_006724438                                                           15    9605
XP_005261889                                                           15    9605
XP_005261888                                                           15    9605
XP_005259990                                                           15    9605
XP_006722828                                                           15    9605
XP_006720745                                                           15    9605
XP_005254716                                                           15    9605
XP_006720744                                                           15    9605
XP_006720743                                                           15    9605
XP_006720742                                                           15    9605
XP_006720740                                                           15    9605
XP_005266289                                                           15    9605
XP_005266288                                                           15    9605
XP_005248557                                                           15    9605
XP_005248558                                                           15    9605
XP_005270983                                                           15    9605
XP_005270981                                                           15    9605
XP_005270982                                                           15    9605
XP_006710743                                                           15    9605
XP_005270980                                                           15    9605
NP_001032417                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KN LRNMVM
Sbjct: 3606 KNDLRNMVM 3614
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KN LRNMVM
Sbjct: 3598 KNDLRNMVM 3606
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KN LRNMVM
Sbjct: 3559 KNDLRNMVM 3567
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KN LRNMVM
Sbjct: 3638 KNDLRNMVM 3646
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KN LRNMVM
Sbjct: 3651 KNDLRNMVM 3659
>NP_001245240
          Length = 524

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NVLRNMVM 9
           NVL+NMV+
Sbjct: 133 NVLKNMVV 140
>NP_037484
          Length = 958

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KNV RN+++
Sbjct: 552 KNVQRNLIL 560
>NP_001074445
          Length = 958

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KNV RN+++
Sbjct: 552 KNVQRNLIL 560
>NP_001121190
          Length = 1668

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KNV+RN+ M
Sbjct: 329 KNVIRNVHM 337
>NP_001121189
          Length = 3277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KNVLRNMVM 9
            KNV+RN+ M
Sbjct: 1938 KNVIRNVHM 1946
>NP_008966
          Length = 352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KNVLRNM 7
           KN LRNM
Sbjct: 201 KNALRNM 207
>XP_005267010
          Length = 958

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KNV RN+++
Sbjct: 552 KNVQRNLIL 560
>NP_003356
          Length = 480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN+LRN ++
Sbjct: 392 KNILRNALV 400
>NP_937762
          Length = 3333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KNVLRNM 7
            KNV+RN+
Sbjct: 1938 KNVIRNV 1944
>NP_000218
          Length = 1724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           KNV+RN+
Sbjct: 329 KNVIRNV 335
>NP_055616
          Length = 2137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KNVLRNMV 8
            K VLRN++
Sbjct: 1810 KQVLRNLI 1817
>XP_005273329
          Length = 1934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KNVLRNMV 8
            K VLRN++
Sbjct: 1607 KQVLRNLI 1614
>NP_001273596
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_001273595
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_001273594
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_598397
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVLRNMVM 9
           N+LRN+ M
Sbjct: 544 NLLRNVAM 551
>NP_004728
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVLRNMVM 9
           N+LRN+ M
Sbjct: 544 NLLRNVAM 551
>NP_001129406
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_001129407
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_006466
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_001129408
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>NP_001265520
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNVLRNM 7
           KN LRN+
Sbjct: 94  KNTLRNL 100
>NP_001265519
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNVLRNM 7
           KN LRN+
Sbjct: 94  KNTLRNL 100
>NP_919433
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNVLRNM 7
           KN LRN+
Sbjct: 94  KNTLRNL 100
>NP_006850
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNVLRNM 7
           KN LRN+
Sbjct: 94  KNTLRNL 100
>NP_002261
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 241 KNVCRALVM 249
>NP_694858
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 233 KNVCRALVM 241
>NP_001243481
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 232 ENVLRNL 238
>NP_001129668
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 231 KNVCRALVM 239
>NP_078884
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 146 ENVLRNL 152
>NP_001230050
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 560 VLRNMV 565
>NP_001104779
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 521 VLRNMV 526
>NP_006193
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 343 VLRNMV 348
>NP_001104778
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 556 VLRNMV 561
>NP_001104777
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 582 VLRNMV 587
>NP_001258029
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 405 VLRNMV 410
>NP_001129505
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 422 VLRNMV 427
>NP_001129667
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 231 KNVCRALVM 239
>NP_038461
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 231 KNVCRALVM 239
>NP_055096
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 448 VLRNMV 453
>NP_510965
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 465 VLRNMV 470
>NP_001032416
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 383 VLRNMV 388
>NP_002591
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 555 VLRNMV 560
>NP_001258028
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 436 VLRNMV 441
>NP_001258026
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 419 VLRNMV 424
>NP_001032418
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 555 VLRNMV 560
>NP_078895
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   NVLRNMV 8
           N++RN+V
Sbjct: 302 NIMRNLV 308
>NP_001258025
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 447 VLRNMV 452
>NP_001258027
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 464 VLRNMV 469
>XP_006724438
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVLRNMVM 9
           N+LRN+ M
Sbjct: 544 NLLRNVAM 551
>XP_005261889
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVLRNMVM 9
           N+LRN+ M
Sbjct: 544 NLLRNVAM 551
>XP_005261888
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVLRNMVM 9
           N+LRN+ M
Sbjct: 544 NLLRNVAM 551
>XP_005259990
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 278 VLRNMV 283
>XP_006722828
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 395 VLRNMV 400
>XP_006720745
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 146 ENVLRNL 152
>XP_005254716
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 146 ENVLRNL 152
>XP_006720744
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 146 ENVLRNL 152
>XP_006720743
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 146 ENVLRNL 152
>XP_006720742
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 189 ENVLRNL 195
>XP_006720740
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNVLRNM 7
           +NVLRN+
Sbjct: 223 ENVLRNL 229
>XP_005266289
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>XP_005266288
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNVLRNMVM 9
           KN L+N+++
Sbjct: 556 KNALQNIIL 564
>XP_005248557
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 233 KNVCRALVM 241
>XP_005248558
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KNVLRNMVM 9
           KNV R +VM
Sbjct: 241 KNVCRALVM 249
>XP_005270983
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 322 VLRNMV 327
>XP_005270981
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 336 VLRNMV 341
>XP_005270982
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 336 VLRNMV 341
>XP_006710743
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 350 VLRNMV 355
>XP_005270980
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 358 VLRNMV 363
>NP_001032417
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VLRNMV 8
           VLRNMV
Sbjct: 540 VLRNMV 545
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.134    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 325,570
Number of extensions: 496
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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