Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     869
NP_036462                                                              19     869
NP_001243397                                                           19     869
XP_005269721                                                           19     869
NP_620636                                                              18    1935
NP_003062                                                              18    1935
XP_005247781                                                           18    1935
NP_003585                                                              17    3301
XP_005271334                                                           17    3301
XP_006711044                                                           17    3301
XP_006711043                                                           17    3301
XP_006711042                                                           17    3301
NP_003174                                                              16    7355
NP_001157755                                                           15    9605
NP_079410                                                              15    9605
NP_679211                                                              15    9605
NP_001157753                                                           15    9605
NP_659469                                                              15    9605
NP_001104508                                                           15    9605
NP_001274079                                                           15    9605
NP_001171671                                                           15    9605
NP_006768                                                              15    9605
XP_005256233                                                           15    9605
XP_005256232                                                           15    9605
XP_005256231                                                           15    9605
XP_005256229                                                           15    9605
XP_005256228                                                           15    9605
XP_005256227                                                           15    9605
XP_006721346                                                           15    9605
XP_005256226                                                           15    9605
XP_006721345                                                           15    9605
XP_006721344                                                           15    9605
XP_006721343                                                           15    9605
XP_005256225                                                           15    9605
XP_005250270                                                           15    9605
XP_005250269                                                           15    9605
XP_005250266                                                           15    9605
XP_006715960                                                           15    9605
XP_005250265                                                           15    9605
XP_005250264                                                           15    9605
XP_005250262                                                           15    9605
XP_006715382                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNILLR SK
Sbjct: 469 KNILLRHSK 477
>NP_036462
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNILLR SK
Sbjct: 761 KNILLRHSK 769
>NP_001243397
          Length = 1890

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNILLR SK
Sbjct: 578 KNILLRHSK 586
>XP_005269721
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNILLR SK
Sbjct: 761 KNILLRHSK 769
>NP_620636
          Length = 1009

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNI LRR+K
Sbjct: 638 KNITLRRTK 646
>NP_003062
          Length = 1009

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNI LRR+K
Sbjct: 638 KNITLRRTK 646
>XP_005247781
          Length = 1008

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KNILLRRSK 9
           KNI LRR+K
Sbjct: 637 KNITLRRTK 645
>NP_003585
          Length = 1162

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           K++LLRR+K
Sbjct: 814 KSLLLRRTK 822
>XP_005271334
          Length = 1161

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           K++LLRR+K
Sbjct: 813 KSLLLRRTK 821
>XP_006711044
          Length = 1168

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           K++LLRR+K
Sbjct: 820 KSLLLRRTK 828
>XP_006711043
          Length = 1169

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           K++LLRR+K
Sbjct: 821 KSLLLRRTK 829
>XP_006711042
          Length = 1169

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           K++LLRR+K
Sbjct: 821 KSLLLRRTK 829
>NP_003174
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNILLRRSK 9
           KN+ LR+ K
Sbjct: 620 KNLFLRKGK 628
>NP_001157755
          Length = 109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 81 KNILLR 86
>NP_079410
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>NP_679211
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 537 KNILLR 542
>NP_001157753
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 536 KNILLR 541
>NP_659469
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 72 KNILLR 77
>NP_001104508
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 72 KNILLR 77
>NP_001274079
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 72 KNILLR 77
>NP_001171671
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           KN+++++SK
Sbjct: 145 KNLVIQKSK 153
>NP_006768
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KNILLRRSK 9
           KN+++++SK
Sbjct: 145 KNLVIQKSK 153
>XP_005256233
          Length = 2391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ILLRRSK 9
           ILLRR+K
Sbjct: 875 ILLRRTK 881
>XP_005256232
          Length = 2424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ILLRRSK 9
           ILLRR+K
Sbjct: 908 ILLRRTK 914
>XP_005256231
          Length = 2573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256229
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256228
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256227
          Length = 2897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721346
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256226
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721345
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721344
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721343
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256225
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ILLRRSK 9
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005250270
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 72 KNILLR 77
>XP_005250269
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 162 KNILLR 167
>XP_005250266
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 72 KNILLR 77
>XP_006715960
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 74 KNILLR 79
>XP_005250265
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 162 KNILLR 167
>XP_005250264
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 162 KNILLR 167
>XP_005250262
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KNILLR 6
           KNILLR
Sbjct: 162 KNILLR 167
>XP_006715382
          Length = 109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KNILLR 6
          KNILLR
Sbjct: 81 KNILLR 86
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.139    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,112
Number of extensions: 511
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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