Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_057225                                                              19     869
NP_004963                                                              18    1482
XP_005251512                                                           18    1482
NP_006132                                                              17    2528
NP_001273086                                                           17    2528
NP_001360                                                              17    4312
XP_005248319                                                           17    4312
NP_002379                                                              16    5631
NP_001257401                                                           16    5631
NP_002935                                                              16    5631
NP_001753                                                              16    5631
NP_150091                                                              16    5631
NP_001121689                                                           16    5631
NP_001273648                                                           16    5631
NP_057117                                                              16    5631
NP_006575                                                              16    5631
NP_001180458                                                           16    5631
XP_005259832                                                           16    5631
XP_005259830                                                           16    5631
XP_006721705                                                           16    5631
XP_006721704                                                           16    5631
XP_006716637                                                           16    5631
XP_005251005                                                           16    5631
XP_006716636                                                           16    5631
XP_005251004                                                           16    5631
XP_005251002                                                           16    5631
XP_005251001                                                           16    5631
XP_006715611                                                           16    5631
NP_060372                                                              16    7355
NP_115717                                                              16    7355
NP_057613                                                              16    7355
XP_006719899                                                           16    7355
XP_006719898                                                           16    7355
XP_006719897                                                           16    7355
XP_006719896                                                           16    7355
XP_006719895                                                           16    7355
XP_005266476                                                           16    7355
NP_001001711                                                           16    7355
NP_940980                                                              15    9605
NP_998758                                                              15    9605
NP_000783                                                              15    9605
NP_002255                                                              15    9605
NP_443125                                                              15    9605
NP_001099001                                                           15    9605
NP_079114                                                              15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
NP_001158283                                                           15    9605
XP_005268686                                                           15    9605
XP_005252654                                                           15    9605
XP_005248808                                                           15    9605
XP_005248807                                                           15    9605
XP_005248806                                                           15    9605
XP_005248805                                                           15    9605
XP_005248804                                                           15    9605
XP_005248803                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
XP_005267021                                                           15    9605
XP_006715537                                                           15    9605
XP_005248898                                                           15    9605
XP_005247496                                                           15    9605
XP_005247494                                                           15    9605
XP_005270768                                                           15    9605
NP_001092742                                                           15    9605
NP_803875                                                              15    9605
NP_001034805                                                           15    9605
NP_001034804                                                           15    9605
NP_036448                                                              15    9605
NP_002260                                                              15    9605
>NP_057225
          Length = 523

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  KNILLIGEE 9
          KN+LL+GE+
Sbjct: 68 KNVLLLGED 76
>NP_004963
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           KNILLI EE
Sbjct: 677 KNILLIREE 685
>XP_005251512
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           KNILLI EE
Sbjct: 677 KNILLIREE 685
>NP_006132
          Length = 492

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          KNIL+ GE+
Sbjct: 55 KNILVFGED 63
>NP_001273086
          Length = 415

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          KNIL+ GE+
Sbjct: 55 KNILVFGED 63
>NP_001360
          Length = 4624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KNILLIGEE 9
            K +LLIGE+
Sbjct: 2584 KAVLLIGEQ 2592
>XP_005248319
          Length = 4609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KNILLIGEE 9
            K +LLIGE+
Sbjct: 2569 KAVLLIGEQ 2577
>NP_002379
          Length = 853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           NILLIG+
Sbjct: 385 NILLIGD 391
>NP_001257401
          Length = 818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           NILLIG+
Sbjct: 350 NILLIGD 356
>NP_002935
          Length = 2347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    KNILLIGEE 9
            +NI+L+G++
Sbjct: 1846 ENIILVGDD 1854
>NP_001753
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>NP_150091
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KNILLIGE 8
           KN+ L+GE
Sbjct: 424 KNMFLVGE 431
>NP_001121689
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KNILLIGE 8
           KN+ L+GE
Sbjct: 424 KNMFLVGE 431
>NP_001273648
          Length = 284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 231 KNLLLLGK 238
>NP_057117
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 261 KNLLLLGK 268
>NP_006575
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>NP_001180458
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>XP_005259832
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          KN++++G E
Sbjct: 42 KNLIILGSE 50
>XP_005259830
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          KN++++G E
Sbjct: 42 KNLIILGSE 50
>XP_006721705
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  NILLIGE 8
          N+L+IGE
Sbjct: 29 NVLIIGE 35
>XP_006721704
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILLIGE 8
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>XP_006716637
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 261 KNLLLLGK 268
>XP_005251005
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 217 KNLLLLGK 224
>XP_006716636
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 217 KNLLLLGK 224
>XP_005251004
          Length = 353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 231 KNLLLLGK 238
>XP_005251002
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 261 KNLLLLGK 268
>XP_005251001
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KNILLIGE 8
           KN+LL+G+
Sbjct: 261 KNLLLLGK 268
>XP_006715611
          Length = 2342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    KNILLIGEE 9
            +NI+L+G++
Sbjct: 1841 ENIILVGDD 1849
>NP_060372
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILLIGEE 9
           N+LLIG E
Sbjct: 185 NLLLIGME 192
>NP_115717
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+L+IG
Sbjct: 338 KNVLVIG 344
>NP_057613
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 669 KNLLLLG 675
>XP_006719899
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719898
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719897
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719896
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 486 KNLLLLG 492
>XP_006719895
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 563 KNLLLLG 569
>XP_005266476
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>NP_001001711
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KNILLIG 7
           KN+L+IG
Sbjct: 346 KNVLVIG 352
>NP_940980
          Length = 2527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    KNILLIG 7
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>NP_998758
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          +NIL +GE+
Sbjct: 39 RNILAMGEK 47
>NP_000783
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          +NIL +GE+
Sbjct: 39 RNILAMGEK 47
>NP_002255
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 448 ENILRLGEQ 456
>NP_443125
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LLIGEE 9
          LLIGEE
Sbjct: 29 LLIGEE 34
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1219 KNVVLVG 1225
>NP_079114
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KNILLIG 7
          KNI+L+G
Sbjct: 56 KNIILMG 62
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1202 KNVVLVG 1208
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>NP_001158283
          Length = 81

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          +NI L+GE+
Sbjct: 50 ENIRLLGEQ 58
>XP_005268686
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    KNILLIG 7
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>XP_005252654
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KNILLIG 7
          KNI+L+G
Sbjct: 56 KNIILMG 62
>XP_005248808
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1021 KNVVLVG 1027
>XP_005248807
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1082 KNVVLVG 1088
>XP_005248806
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1217 KNVVLVG 1223
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1245 KNVVLVG 1251
>XP_005248804
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1278 KNVVLVG 1284
>XP_005248803
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1355 KNVVLVG 1361
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    KNILLIG 7
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
>XP_005267021
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 446 ENILRLGEQ 454
>XP_006715537
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 449 ENILRLGEQ 457
>XP_005248898
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LLIGEE 9
          LLIGEE
Sbjct: 29 LLIGEE 34
>XP_005247496
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 247 ENILRLGEQ 255
>XP_005247494
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 448 ENILRLGEQ 456
>XP_005270768
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 476 ENILRLGEQ 484
>NP_001092742
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LLIGEE 9
          LLIGEE
Sbjct: 29 LLIGEE 34
>NP_803875
          Length = 4243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KNILLIGEE 9
            +NI ++GE+
Sbjct: 3259 RNIKIVGED 3267
>NP_001034805
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          +NIL +GE+
Sbjct: 39 RNILAMGEK 47
>NP_001034804
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNILLIGEE 9
          +NIL +GE+
Sbjct: 39 RNILAMGEK 47
>NP_036448
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 446 ENILRLGEQ 454
>NP_002260
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNILLIGEE 9
           +NIL +GE+
Sbjct: 449 ENILRLGEQ 457
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.147    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,069
Number of extensions: 1027
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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