Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_659547                                                              17    3301
XP_005255220                                                           17    3301
XP_006721086                                                           17    3301
NP_652760                                                              17    4312
NP_001263191                                                           17    4312
NP_001269851                                                           17    4312
NP_001269852                                                           17    4312
NP_001263189                                                           17    4312
NP_602299                                                              17    4312
NP_001263190                                                           17    4312
NP_652759                                                              17    4312
NP_570613                                                              17    4312
XP_006717293                                                           17    4312
XP_006717292                                                           17    4312
XP_006717291                                                           17    4312
XP_006717290                                                           17    4312
XP_006717289                                                           17    4312
XP_006717288                                                           17    4312
XP_006717287                                                           17    4312
XP_006717285                                                           17    4312
XP_006717284                                                           17    4312
XP_006717283                                                           17    4312
XP_006717282                                                           17    4312
NP_001035351                                                           16    5631
NP_001035350                                                           16    5631
NP_001182345                                                           16    5631
NP_004725                                                              16    5631
NP_001182344                                                           16    5631
XP_006719956                                                           16    5631
XP_005266649                                                           16    5631
XP_005262843                                                           16    5631
XP_005262842                                                           16    5631
NP_001273564                                                           16    7355
NP_001135916                                                           16    7355
NP_001135915                                                           16    7355
NP_079359                                                              16    7355
NP_065928                                                              16    7355
XP_005256527                                                           16    7355
XP_006715080                                                           16    7355
NP_689947                                                              16    7355
NP_001012418                                                           15    9605
NP_001265436                                                           15    9605
NP_001092882                                                           15    9605
NP_006757                                                              15    9605
NP_001092883                                                           15    9605
NP_001139131                                                           15    9605
NP_001264262                                                           15    9605
NP_001008747                                                           15    9605
NP_001264307                                                           15    9605
XP_003959998                                                           15    9605
XP_005273706                                                           15    9605
XP_005249137                                                           15    9605
XP_006715147                                                           15    9605
XP_006715146                                                           15    9605
XP_006715145                                                           15    9605
XP_006715144                                                           15    9605
XP_005249136                                                           15    9605
XP_005249134                                                           15    9605
XP_005249135                                                           15    9605
NP_940897                                                              15    9605
NP_758441                                                              15    9605
>NP_659547
          Length = 266

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ +FRK
Sbjct: 103 ENELDLFRK 111
>XP_005255220
          Length = 266

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ +FRK
Sbjct: 103 ENELDLFRK 111
>XP_006721086
          Length = 266

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ +FRK
Sbjct: 103 ENELDLFRK 111
>NP_652760
          Length = 311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 145 KNKLGIFRR 153
>NP_001263191
          Length = 168

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNEISIFRK 9
          KN++ IFR+
Sbjct: 2  KNKLGIFRR 10
>NP_001269851
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>NP_001269852
          Length = 1088

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 922 KNKLGIFRR 930
>NP_001263189
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>NP_602299
          Length = 168

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KNEISIFRK 9
          KN++ IFR+
Sbjct: 2  KNKLGIFRR 10
>NP_001263190
          Length = 591

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 425 KNKLGIFRR 433
>NP_652759
          Length = 1198

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KNEISIFRK 9
            KN++ IFR+
Sbjct: 1032 KNKLGIFRR 1040
>NP_570613
          Length = 917

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 751 KNKLGIFRR 759
>XP_006717293
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>XP_006717292
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>XP_006717291
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>XP_006717290
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>XP_006717289
          Length = 519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 353 KNKLGIFRR 361
>XP_006717288
          Length = 521

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 355 KNKLGIFRR 363
>XP_006717287
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 371 KNKLGIFRR 379
>XP_006717285
          Length = 824

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 658 KNKLGIFRR 666
>XP_006717284
          Length = 961

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 795 KNKLGIFRR 803
>XP_006717283
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 920 KNKLGIFRR 928
>XP_006717282
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           KN++ IFR+
Sbjct: 928 KNKLGIFRR 936
>NP_001035351
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 455 ENEVSILRR 463
>NP_001035350
          Length = 766

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 438 ENEVSILRR 446
>NP_001182345
          Length = 433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 127 QNEVSILRR 135
>NP_004725
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 434 QNEVSILRR 442
>NP_001182344
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 127 QNEVSILRR 135
>XP_006719956
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 434 QNEVSILRR 442
>XP_005266649
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 434 QNEVSILRR 442
>XP_005262843
          Length = 765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 437 ENEVSILRR 445
>XP_005262842
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+SI R+
Sbjct: 454 ENEVSILRR 462
>NP_001273564
          Length = 347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NEISIFRK 9
          NEISI+ K
Sbjct: 6  NEISIYDK 13
>NP_001135916
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NEISIFRK 9
           NE+S+F K
Sbjct: 380 NELSLFSK 387
>NP_001135915
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NEISIFRK 9
           NE+S+F K
Sbjct: 380 NELSLFSK 387
>NP_079359
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NEISIFRK 9
           NE+S+F K
Sbjct: 380 NELSLFSK 387
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    KNEISIFRK 9
            KN++SI  K
Sbjct: 1684 KNQVSILNK 1692
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    KNEISIFRK 9
            KN++SI  K
Sbjct: 1684 KNQVSILNK 1692
>XP_006715080
          Length = 347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NEISIFRK 9
          NEISI+ K
Sbjct: 6  NEISIYDK 13
>NP_689947
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NEISIFRK 9
          NEISI+ K
Sbjct: 13 NEISIYDK 20
>NP_001012418
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>NP_001265436
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ ++RK
Sbjct: 393 ENEMKLYRK 401
>NP_001092882
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNEISIF 7
           KN IS+F
Sbjct: 573 KNNISVF 579
>NP_006757
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNEISIF 7
           KN IS+F
Sbjct: 573 KNNISVF 579
>NP_001092883
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNEISIF 7
           KN IS+F
Sbjct: 573 KNNISVF 579
>NP_001139131
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ ++RK
Sbjct: 393 ENEMKLYRK 401
>NP_001264262
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KN IS+ +K
Sbjct: 450 KNNISVLQK 458
>NP_001008747
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ ++RK
Sbjct: 393 ENEMKLYRK 401
>NP_001264307
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NEISIFR 8
           +E+SIFR
Sbjct: 209 HEVSIFR 215
>XP_003959998
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KN IS+ +K
Sbjct: 172 KNNISVLQK 180
>XP_005273706
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KNEISIF 7
           KN IS+F
Sbjct: 566 KNNISVF 572
>XP_005249137
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>XP_006715147
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KNEISIFRK 9
          KNEIS+  +
Sbjct: 84 KNEISVMNQ 92
>XP_006715146
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 138 KNEISVMNQ 146
>XP_006715145
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 143 KNEISVMNQ 151
>XP_006715144
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>XP_005249136
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>XP_005249134
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>XP_005249135
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KNEISIFRK 9
           KNEIS+  +
Sbjct: 149 KNEISVMNQ 157
>NP_940897
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ ++RK
Sbjct: 393 ENEMKLYRK 401
>NP_758441
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KNEISIFRK 9
           +NE+ ++RK
Sbjct: 361 ENEMKLYRK 369
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.138    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 381,579
Number of extensions: 588
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package