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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              20     390
NP_001273988                                                           16    5631
NP_055867                                                              16    5631
NP_065811                                                              16    5631
XP_006719129                                                           16    5631
XP_006719128                                                           16    5631
XP_006715736                                                           16    5631
XP_006715735                                                           16    5631
XP_005249722                                                           16    5631
XP_006715734                                                           16    5631
XP_006715733                                                           16    5631
XP_006712712                                                           16    5631
XP_006712711                                                           16    5631
XP_006712710                                                           16    5631
XP_006712709                                                           16    5631
NP_001230013                                                           16    7355
NP_851397                                                              16    7355
NP_001521                                                              16    7355
NP_149023                                                              16    7355
NP_149083                                                              16    7355
NP_149084                                                              16    7355
NP_001010872                                                           16    7355
XP_005253241                                                           16    7355
XP_005253240                                                           16    7355
XP_006715085                                                           16    7355
NP_001155973                                                           15    9605
NP_001020014                                                           15    9605
NP_055903                                                              15    9605
NP_001269385                                                           15    9605

>NP_002430
          Length = 1137

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KMGVVKQTE 9
           K+GVVKQTE
Sbjct: 303 KVGVVKQTE 311



>NP_001273988
          Length = 1572

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1417 GVVQQTE 1423



>NP_055867
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1451 GVVQQTE 1457



>NP_065811
          Length = 1572

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1417 GVVQQTE 1423



>XP_006719129
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KMGVVKQT 8
           K+GV++QT
Sbjct: 182 KLGVLRQT 189



>XP_006719128
          Length = 236

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KMGVVKQT 8
           K+GV++QT
Sbjct: 213 KLGVLRQT 220



>XP_006715736
          Length = 1573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1418 GVVQQTE 1424



>XP_006715735
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1451 GVVQQTE 1457



>XP_005249722
          Length = 1607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1452 GVVQQTE 1458



>XP_006715734
          Length = 1607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1452 GVVQQTE 1458



>XP_006715733
          Length = 1608

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1453 GVVQQTE 1459



>XP_006712712
          Length = 1414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1259 GVVQQTE 1265



>XP_006712711
          Length = 1448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1293 GVVQQTE 1299



>XP_006712710
          Length = 1528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1373 GVVQQTE 1379



>XP_006712709
          Length = 1579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    GVVKQTE 9
            GVV+QTE
Sbjct: 1424 GVVQQTE 1430



>NP_001230013
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV++QTE
Sbjct: 699 GVIEQTE 705



>NP_851397
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV++QTE
Sbjct: 675 GVIEQTE 681



>NP_001521
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV++QTE
Sbjct: 675 GVIEQTE 681



>NP_149023
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 252 GVIKRTE 258



>NP_149083
          Length = 347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 252 GVIKRTE 258



>NP_149084
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 252 GVIKRTE 258



>NP_001010872
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MGVVKQTE 9
           +GV KQTE
Sbjct: 642 LGVNKQTE 649



>XP_005253241
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 252 GVIKRTE 258



>XP_005253240
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 252 GVIKRTE 258



>XP_006715085
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MGVVKQTE 9
           +GV KQTE
Sbjct: 642 LGVNKQTE 649



>NP_001155973
          Length = 1833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MGVVKQTE 9
            MG++ QTE
Sbjct: 1069 MGLLSQTE 1076



>NP_001020014
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MGVVKQTE 9
           MG++ QTE
Sbjct: 322 MGLLSQTE 329



>NP_055903
          Length = 1723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MGVVKQTE 9
            MG++ QTE
Sbjct: 1016 MGLLSQTE 1023



>NP_001269385
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVVKQTE 9
           GV+K+TE
Sbjct: 124 GVLKETE 130



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.121    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 383,097
Number of extensions: 546
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)