Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001157994                                                           19     665
XP_006711351                                                           19     665
NP_796377                                                              19     665
NP_789765                                                              18    1935
NP_001123914                                                           18    1935
NP_005334                                                              18    1935
NP_004976                                                              18    1935
NP_203524                                                              18    1935
NP_002515                                                              18    1935
NP_001138528                                                           18    1935
NP_065161                                                              18    1935
XP_006725199                                                           18    1935
XP_005260056                                                           18    1935
XP_005260055                                                           18    1935
XP_005260054                                                           18    1935
XP_006719132                                                           18    1935
XP_006718280                                                           18    1935
NP_006261                                                              16    5631
NP_001405                                                              16    7355
NP_006047                                                              16    7355
XP_006715335                                                           16    7355
XP_006712259                                                           16    7355
XP_006712258                                                           16    7355
NP_001137442                                                           16    7355
NP_001137443                                                           16    7355
NP_004815                                                              16    7355
NP_001078518                                                           15    9605
NP_036351                                                              15    9605
NP_000080                                                              15    9605
NP_001239019                                                           15    9605
NP_620598                                                              15    9605
NP_620599                                                              15    9605
NP_004348                                                              15    9605
NP_001034579                                                           15    9605
NP_000099                                                              15    9605
NP_001238851                                                           15    9605
NP_001238847                                                           15    9605
NP_001238846                                                           15    9605
NP_056461                                                              15    9605
NP_001238850                                                           15    9605
NP_001010942                                                           15    9605
NP_001243750                                                           15    9605
NP_008843                                                              15    9605
NP_003310                                                              15    9605
NP_001276680                                                           15    9605
NP_597676                                                              15    9605
NP_002200                                                              15    9605
NP_001276679                                                           15    9605
NP_596870                                                              15    9605
NP_001243779                                                           15    9605
NP_001107852                                                           15    9605
NP_036344                                                              15    9605
NP_596869                                                              15    9605
NP_001276681                                                           15    9605
NP_002198                                                              15    9605
NP_001158297                                                           15    9605
NP_001139581                                                           15    9605
NP_001139580                                                           15    9605
NP_001158296                                                           15    9605
NP_612437                                                              15    9605
NP_001760                                                              15    9605
NP_056535                                                              15    9605
XP_006721107                                                           15    9605
XP_005255370                                                           15    9605
XP_005247286                                                           15    9605
XP_005247285                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_006710866                                                           15    9605
XP_005270460                                                           15    9605
NP_001010935                                                           15    9605
NP_002875                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_001157994
          Length = 199

 Score = 19.2 bits (38), Expect =   665
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  KLVVVGAVG 9
          KL++VGA+G
Sbjct: 10 KLIIVGAIG 18
>XP_006711351
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  KLVVVGAVG 9
          KL++VGA+G
Sbjct: 10 KLIIVGAIG 18
>NP_796377
          Length = 199

 Score = 19.2 bits (38), Expect =   665
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  KLVVVGAVG 9
          KL++VGA+G
Sbjct: 10 KLIIVGAIG 18
>NP_789765
          Length = 170

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_001123914
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_005334
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_004976
          Length = 188

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_203524
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_002515
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_001138528
          Length = 704

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLVVVGAVG 9
           KL++VG+VG
Sbjct: 604 KLLIVGSVG 612
>NP_065161
          Length = 706

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLVVVGAVG 9
           KL++VG+VG
Sbjct: 606 KLLIVGSVG 614
>XP_006725199
          Length = 170

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>XP_005260056
          Length = 709

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLVVVGAVG 9
           KL++VG+VG
Sbjct: 604 KLLIVGSVG 612
>XP_005260055
          Length = 711

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLVVVGAVG 9
           KL++VG+VG
Sbjct: 606 KLLIVGSVG 614
>XP_005260054
          Length = 711

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLVVVGAVG 9
           KL++VG+VG
Sbjct: 606 KLLIVGSVG 614
>XP_006719132
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>XP_006718280
          Length = 170

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_006261
          Length = 218

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 31 KLVVVGGGG 39
>NP_001405
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGAVG 9
           LV+VGA G
Sbjct: 192 LVIVGAEG 199
>NP_006047
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LVVVGAVG 9
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>XP_006715335
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGAVG 9
           KLV++ AVG
Sbjct: 339 KLVLLSAVG 347
>XP_006712259
          Length = 333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LVVVGAVG 9
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>XP_006712258
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LVVVGAVG 9
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>NP_001137442
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGAVG 9
           KLV++ AVG
Sbjct: 202 KLVLLSAVG 210
>NP_001137443
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGAVG 9
           KLV++ AVG
Sbjct: 202 KLVLLSAVG 210
>NP_004815
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGAVG 9
           KLV++ AVG
Sbjct: 334 KLVLLSAVG 342
>NP_001078518
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_036351
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_000080
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 626 VVGAVG 631
>NP_001239019
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_620598
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGAVG 9
           L V+GAVG
Sbjct: 220 LRVIGAVG 227
>NP_620599
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGAVG 9
           L V+GAVG
Sbjct: 220 LRVIGAVG 227
>NP_004348
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGAVG 9
           L V+GAVG
Sbjct: 220 LRVIGAVG 227
>NP_001034579
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGAVG 9
           L V+GAVG
Sbjct: 220 LRVIGAVG 227
>NP_000099
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 215 KMVVIGA 221
>NP_001238851
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238847
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238846
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_056461
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238850
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001010942
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001243750
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLV++GA G
Sbjct: 40 KLVMLGAGG 48
>NP_008843
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLV++GA G
Sbjct: 23 KLVMLGAGG 31
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2213 KLIVEGAV 2220
>NP_001276680
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 192 KMVVIGA 198
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2213 KLIVEGAV 2220
>NP_002200
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 364 VVGAVG 369
>NP_001276679
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 116 KMVVIGA 122
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2259 KLIVEGAV 2266
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2259 KLIVEGAV 2266
>NP_001107852
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 281 VVGAVG 286
>NP_036344
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2259 KLIVEGAV 2266
>NP_001276681
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 167 KMVVIGA 173
>NP_002198
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGAVG 9
           +LVV+GA G
Sbjct: 205 ELVVMGAPG 213
>NP_001158297
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VVGAVG 9
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001139581
          Length = 301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_001139580
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_001158296
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VVGAVG 9
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_612437
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VVGAVG 9
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001760
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KLVVVGAVG 9
           K  ++GAVG
Sbjct: 192 KFHIIGAVG 200
>NP_056535
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LVVVGAV 8
           LVV+GA+
Sbjct: 505 LVVIGAI 511
>XP_006721107
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 281 VVGAVG 286
>XP_005255370
          Length = 1169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVGAVG 9
           VVGAVG
Sbjct: 364 VVGAVG 369
>XP_005247286
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>XP_005247285
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGAVG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2260 KLIVEGAV 2267
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2260 KLIVEGAV 2267
>XP_006710866
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>XP_005270460
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VVGAVG 9
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001010935
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_002875
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGAVG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2259 KLIVEGAV 2266
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KLVVVGAV 8
            KL+V GAV
Sbjct: 2213 KLIVEGAV 2220
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.147    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 333,357
Number of extensions: 807
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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