Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_789765                                                              19     869
NP_001123914                                                           19     869
NP_005334                                                              19     869
NP_004976                                                              19     869
NP_203524                                                              19     869
NP_002515                                                              19     869
XP_006725199                                                           19     869
XP_006719132                                                           19     869
XP_006718280                                                           19     869
NP_853510                                                              18    1135
NP_076429                                                              18    1482
NP_006261                                                              17    2528
NP_001157994                                                           17    2528
XP_006711351                                                           17    2528
NP_796377                                                              17    2528
NP_056400                                                              17    3301
XP_005260753                                                           17    3301
XP_005260752                                                           17    3301
XP_005260751                                                           17    3301
XP_005260750                                                           17    3301
XP_005260749                                                           17    3301
XP_005260748                                                           17    3301
XP_005260747                                                           17    3301
XP_005260746                                                           17    3301
XP_005260745                                                           17    3301
NP_001078518                                                           17    4312
NP_036351                                                              17    4312
NP_001405                                                              17    4312
NP_001239019                                                           17    4312
NP_005909                                                              17    4312
NP_001238851                                                           17    4312
NP_001238847                                                           17    4312
NP_001238846                                                           17    4312
NP_056461                                                              17    4312
NP_001238850                                                           17    4312
NP_001010942                                                           17    4312
NP_057086                                                              17    4312
NP_001243750                                                           17    4312
NP_008843                                                              17    4312
NP_001269332                                                           17    4312
XP_005247286                                                           17    4312
XP_005247285                                                           17    4312
XP_006710866                                                           17    4312
NP_001010935                                                           17    4312
NP_002875                                                              17    4312
NP_001138890                                                           16    7355
NP_002198                                                              16    7355
XP_006724234                                                           16    7355
XP_005261462                                                           16    7355
NP_008927                                                              15    9605
NP_775759                                                              15    9605
NP_001275933                                                           15    9605
NP_000099                                                              15    9605
NP_001275931                                                           15    9605
NP_006316                                                              15    9605
NP_001276680                                                           15    9605
NP_001276679                                                           15    9605
NP_001276681                                                           15    9605
NP_001438                                                              15    9605
NP_061907                                                              15    9605
XP_006714824                                                           15    9605
XP_005271931                                                           15    9605
>NP_789765
          Length = 170

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_001123914
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_005334
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_004976
          Length = 188

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_203524
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_002515
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>XP_006725199
          Length = 170

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>XP_006719132
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>XP_006718280
          Length = 170

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVVVGA G
Sbjct: 5  KLVVVGAGG 13
>NP_853510
          Length = 233

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          K VVVGASG
Sbjct: 43 KAVVVGASG 51
>NP_076429
          Length = 248

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          K+ VVGASG
Sbjct: 35 KIAVVGASG 43
>NP_006261
          Length = 218

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 31 KLVVVGGGG 39
>NP_001157994
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KL++VGA G
Sbjct: 10 KLIIVGAIG 18
>XP_006711351
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KL++VGA G
Sbjct: 10 KLIIVGAIG 18
>NP_796377
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KL++VGA G
Sbjct: 10 KLIIVGAIG 18
>NP_056400
          Length = 1237

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 667 KIIVVGAS 674
>XP_005260753
          Length = 846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 276 KIIVVGAS 283
>XP_005260752
          Length = 1046

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 476 KIIVVGAS 483
>XP_005260751
          Length = 1060

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 490 KIIVVGAS 497
>XP_005260750
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 672 KIIVVGAS 679
>XP_005260749
          Length = 1211

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 641 KIIVVGAS 648
>XP_005260748
          Length = 1216

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 646 KIIVVGAS 653
>XP_005260747
          Length = 1217

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 647 KIIVVGAS 654
>XP_005260746
          Length = 1237

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 667 KIIVVGAS 674
>XP_005260745
          Length = 1242

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLVVVGAS 8
           K++VVGAS
Sbjct: 672 KIIVVGAS 679
>NP_001078518
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_036351
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_001405
          Length = 305

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGASG 9
           LV+VGA G
Sbjct: 192 LVIVGAEG 199
>NP_001239019
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>NP_005909
          Length = 338

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          K+ V+GASG
Sbjct: 26 KVAVLGASG 34
>NP_001238851
          Length = 137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238847
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238846
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_056461
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001238850
          Length = 165

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001010942
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_057086
          Length = 429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  LVVVGASG 9
          LVV GASG
Sbjct: 10 LVVFGASG 17
>NP_001243750
          Length = 236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLV++GA G
Sbjct: 40 KLVMLGAGG 48
>NP_008843
          Length = 219

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLV++GA G
Sbjct: 23 KLVMLGAGG 31
>NP_001269332
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          K+ V+GASG
Sbjct: 26 KVAVLGASG 34
>XP_005247286
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>XP_005247285
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLVVVG  G
Sbjct: 15 KLVVVGDGG 23
>XP_006710866
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001010935
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_002875
          Length = 184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLVVVGASG 9
          KLVV+G+ G
Sbjct: 5  KLVVLGSGG 13
>NP_001138890
          Length = 2481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KLVVVGAS 8
            KLVV+G+S
Sbjct: 1619 KLVVLGSS 1626
>NP_002198
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLVVVGASG 9
           +LVV+GA G
Sbjct: 205 ELVVMGAPG 213
>XP_006724234
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KLVVVGAS 8
            KLVV+G+S
Sbjct: 1501 KLVVLGSS 1508
>XP_005261462
          Length = 2473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KLVVVGAS 8
            KLVV+G+S
Sbjct: 1619 KLVVLGSS 1626
>NP_008927
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVVVGASG 9
           L+VV ASG
Sbjct: 440 LIVVDASG 447
>NP_775759
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LVVVGAS 8
           LV++GAS
Sbjct: 397 LVIIGAS 403
>NP_001275933
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LVVVGAS 8
           LV++GAS
Sbjct: 335 LVIIGAS 341
>NP_000099
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 215 KMVVIGA 221
>NP_001275931
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LVVVGAS 8
           LV++GAS
Sbjct: 397 LVIIGAS 403
>NP_006316
          Length = 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          KLV+VG  G
Sbjct: 12 KLVLVGDGG 20
>NP_001276680
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 192 KMVVIGA 198
>NP_001276679
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 116 KMVVIGA 122
>NP_001276681
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLVVVGA 7
           K+VV+GA
Sbjct: 167 KMVVIGA 173
>NP_001438
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVVVGASG 9
            LV++GA G
Sbjct: 1987 LVILGAQG 1994
>NP_061907
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KLVVVGASG 9
          K+V+VG  G
Sbjct: 21 KIVIVGDGG 29
>XP_006714824
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVVVGASG 9
            LV++GA G
Sbjct: 1987 LVILGAQG 1994
>XP_005271931
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LVVVGAS 8
           LV++GAS
Sbjct: 397 LVIIGAS 403
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.136    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,578
Number of extensions: 870
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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