Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1482
NP_002760                                                              16    5631
NP_055515                                                              15    9605
XP_006725309                                                           15    9605
XP_006725308                                                           15    9605
XP_006725307                                                           15    9605
XP_006725306                                                           15    9605
XP_006725305                                                           15    9605
XP_005255772                                                           15    9605
XP_005255771                                                           15    9605
XP_006721051                                                           15    9605
XP_006721050                                                           15    9605
XP_005255770                                                           15    9605
NP_001135744                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLSSRAVAR 9
            K SSRAVAR
Sbjct: 1154 KFSSRAVAR 1162
>NP_002760
          Length = 247

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   KLSSRAV 7
           KLSSRAV
Sbjct: 112 KLSSRAV 118
>NP_055515
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 426 RLSSKKVAR 434
>XP_006725309
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 161 RLSSKKVAR 169
>XP_006725308
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 175 RLSSKKVAR 183
>XP_006725307
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>XP_006725306
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>XP_006725305
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>XP_005255772
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 161 RLSSKKVAR 169
>XP_005255771
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 175 RLSSKKVAR 183
>XP_006721051
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>XP_006721050
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>XP_005255770
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 471 RLSSKKVAR 479
>NP_001135744
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLSSRAVAR 9
           +LSS+ VAR
Sbjct: 130 RLSSKKVAR 138
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.116    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 164,760
Number of extensions: 91
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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