Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_116271                                                              18    1935
NP_005742                                                              17    2528
NP_671714                                                              17    2528
XP_006715890                                                           17    2528
XP_005250160                                                           17    2528
XP_005250159                                                           17    2528
NP_878918                                                              16    5631
NP_055995                                                              16    5631
NP_001094383" target = "next">NP_001094383                                                           16    5631
NP_056012                                                              16    5631
NP_001257313                                                           16    5631
NP_940951                                                              16    5631
NP_060496                                                              16    5631
NP_001230056                                                           16    5631
XP_006720155                                                           16    5631
XP_006720154                                                           16    5631
XP_006720153                                                           16    5631
XP_006720152                                                           16    5631
XP_006720151                                                           16    5631
XP_006720150                                                           16    5631
XP_005267520                                                           16    5631
XP_006720149                                                           16    5631
XP_005267519                                                           16    5631
XP_006720148                                                           16    5631
XP_005267517                                                           16    5631
XP_005267516                                                           16    5631
XP_005267515                                                           16    5631
XP_005267514                                                           16    5631
XP_005267513                                                           16    5631
XP_005267512                                                           16    5631
XP_005267511                                                           16    5631
XP_005274154                                                           16    5631
XP_005270907                                                           16    5631
XP_005270905                                                           16    5631
XP_005270904                                                           16    5631
XP_005270903                                                           16    5631
NP_036546                                                              16    7355
NP_853514                                                              16    7355
NP_003651                                                              16    7355
XP_006723513                                                           16    7355
NP_001231743                                                           15    9605
NP_001231739                                                           15    9605
NP_001231745                                                           15    9605
NP_116071                                                              15    9605
NP_001231744                                                           15    9605
NP_001231742                                                           15    9605
NP_001231737                                                           15    9605
NP_001093322                                                           15    9605
NP_006065                                                              15    9605
NP_001186502                                                           15    9605
NP_001265273                                                           15    9605
NP_001094                                                              15    9605
NP_001265272                                                           15    9605
NP_002262                                                              15    9605
NP_001073005                                                           15    9605
NP_872426                                                              15    9605
XP_005254110                                                           15    9605
XP_005254109                                                           15    9605
XP_005254106                                                           15    9605
XP_005263039                                                           15    9605
XP_005264786                                                           15    9605
XP_006713169                                                           15    9605
XP_005264799                                                           15    9605
XP_006713168                                                           15    9605
XP_005264795                                                           15    9605
XP_005264794                                                           15    9605
XP_006713167                                                           15    9605
XP_006713166                                                           15    9605
XP_006713165                                                           15    9605
XP_005264793                                                           15    9605
XP_005264792                                                           15    9605
NP_803235                                                              15    9605
NP_001555                                                              15    9605
>NP_116271
          Length = 399

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KLQVLLQKA 9
           +L+VLLQKA
Sbjct: 262 RLEVLLQKA 270
>NP_005742
          Length = 3907

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLQVLLQKA 9
            KLQVL QKA
Sbjct: 3525 KLQVLPQKA 3533
>NP_671714
          Length = 3899

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLQVLLQKA 9
            KLQVL QKA
Sbjct: 3517 KLQVLPQKA 3525
>XP_006715890
          Length = 3860

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLQVLLQKA 9
            KLQVL QKA
Sbjct: 3478 KLQVLPQKA 3486
>XP_005250160
          Length = 3939

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLQVLLQKA 9
            KLQVL QKA
Sbjct: 3557 KLQVLPQKA 3565
>XP_005250159
          Length = 3952

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KLQVLLQKA 9
            KLQVL QKA
Sbjct: 3570 KLQVLPQKA 3578
>NP_878918
          Length = 6907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>NP_055995
          Length = 6885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>NP_001094383" target = "next">NP_001094383
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>NP_056012
          Length = 889

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>NP_001257313
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 267 KLEALLQRA 275
>NP_940951
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 267 KLEALLQRA 275
>NP_060496
          Length = 963

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 189 KLQIMLQR 196
>NP_001230056
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KLQVLLQK 8
          KLQ++LQ+
Sbjct: 43 KLQIMLQR 50
>XP_006720155
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720154
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720153
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720152
          Length = 911

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720151
          Length = 915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720150
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_005267520
          Length = 921

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720149
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_005267519
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_006720148
          Length = 926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 110 KLQIMLQR 117
>XP_005267517
          Length = 6883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4793 KLQSLLQK 4800
>XP_005267516
          Length = 6884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005267515
          Length = 6899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005267514
          Length = 6908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005267513
          Length = 6921

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005267512
          Length = 6922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005267511
          Length = 6922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    KLQVLLQK 8
            KLQ LLQK
Sbjct: 4832 KLQSLLQK 4839
>XP_005274154
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           KLQ++LQ+
Sbjct: 189 KLQIMLQR 196
>XP_005270907
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 267 KLEALLQRA 275
>XP_005270905
          Length = 601

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 235 KLEALLQRA 243
>XP_005270904
          Length = 601

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 235 KLEALLQRA 243
>XP_005270903
          Length = 604

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLQVLLQKA 9
           KL+ LLQ+A
Sbjct: 267 KLEALLQRA 275
>NP_036546
          Length = 1393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQ LL+K
Sbjct: 681 KLQALLEK 688
>NP_853514
          Length = 1732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LQVLLQKA 9
           LQV LQKA
Sbjct: 268 LQVSLQKA 275
>NP_003651
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLQVLLQKA 9
           KLQ  LQKA
Sbjct: 360 KLQQTLQKA 368
>XP_006723513
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLQVLLQKA 9
           KLQ  LQKA
Sbjct: 360 KLQQTLQKA 368
>NP_001231743
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>NP_001231739
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>NP_001231745
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>NP_116071
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>NP_001231744
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 127 QLQVLLQQ 134
>NP_001231742
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KLQVLLQK 8
          +LQVLLQ+
Sbjct: 25 QLQVLLQQ 32
>NP_001231737
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>NP_001093322
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQVLLQK 8
           LQVLL+K
Sbjct: 340 LQVLLEK 346
>NP_006065
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQV LQ+
Sbjct: 143 KLQVALQR 150
>NP_001186502
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQV LQ+
Sbjct: 143 KLQVALQR 150
>NP_001265273
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           K Q+LLQK
Sbjct: 212 KEQILLQK 219
>NP_001094
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           K Q+LLQK
Sbjct: 420 KEQILLQK 427
>NP_001265272
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           K Q+LLQK
Sbjct: 420 KEQILLQK 427
>NP_002262
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQ L+QK
Sbjct: 514 KLQELIQK 521
>NP_001073005
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           K QV++QK
Sbjct: 150 KFQVMIQK 157
>NP_872426
          Length = 121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLQVLLQKA 9
          KL+++ QKA
Sbjct: 7  KLELMFQKA 15
>XP_005254110
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQ L+QK
Sbjct: 514 KLQELIQK 521
>XP_005254109
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQ L+QK
Sbjct: 514 KLQELIQK 521
>XP_005254106
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           KLQ L+QK
Sbjct: 514 KLQELIQK 521
>XP_005263039
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLQVLLQKA 9
          +LQ LLQ+A
Sbjct: 41 RLQQLLQRA 49
>XP_005264786
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_006713169
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 127 QLQVLLQQ 134
>XP_005264799
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KLQVLLQK 8
          +LQVLLQ+
Sbjct: 25 QLQVLLQQ 32
>XP_006713168
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KLQVLLQK 8
          +LQVLLQ+
Sbjct: 32 QLQVLLQQ 39
>XP_005264795
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_005264794
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_006713167
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_006713166
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_006713165
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 125 QLQVLLQQ 132
>XP_005264793
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 127 QLQVLLQQ 134
>XP_005264792
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLQVLLQK 8
           +LQVLLQ+
Sbjct: 127 QLQVLLQQ 134
>NP_803235
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLQVLLQK 8
           K QV++QK
Sbjct: 122 KFQVMIQK 129
>NP_001555
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLQVLLQKA 9
          +LQ LLQ+A
Sbjct: 81 RLQQLLQRA 89
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.134    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 376,220
Number of extensions: 1058
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package