Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              18    1135
NP_009297                                                              18    1135
NP_006280                                                              17    3301
NP_055874                                                              17    3301
XP_006720784                                                           17    3301
XP_006720783                                                           17    3301
XP_006720782                                                           17    3301
XP_006720781                                                           17    3301
XP_005254772                                                           17    3301
XP_005254771                                                           17    3301
XP_006720780                                                           17    3301
XP_005254769                                                           17    3301
XP_005254770                                                           17    3301
XP_005254765                                                           17    3301
XP_005254767                                                           17    3301
XP_006720779                                                           17    3301
XP_005254768                                                           17    3301
XP_005254764                                                           17    3301
XP_006716915                                                           17    3301
XP_005251621                                                           17    3301
XP_006710367                                                           16    7355
XP_005270450                                                           16    7355
XP_005270449                                                           16    7355
XP_006710366                                                           16    7355
XP_005270448                                                           16    7355
NP_006811                                                              16    7355
NP_057315                                                              15    9605
XP_005258045                                                           15    9605
>NP_005148
          Length = 1130

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLLSSVKQI 9
            KLLSSVK+I
Sbjct: 1116 KLLSSVKEI 1124
>NP_009297
          Length = 1149

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLLSSVKQI 9
            KLLSSVK+I
Sbjct: 1135 KLLSSVKEI 1143
>NP_006280
          Length = 2541

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2423 KLISSAKQV 2431
>NP_055874
          Length = 2542

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_006720784
          Length = 2502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2384 KLISSAKQV 2392
>XP_006720783
          Length = 2512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2379 KLISSAKQV 2387
>XP_006720782
          Length = 2517

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2384 KLISSAKQV 2392
>XP_006720781
          Length = 2542

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254772
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254771
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_006720780
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254769
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254770
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254765
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254767
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_006720779
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254768
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005254764
          Length = 2557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_006716915
          Length = 2542

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_005251621
          Length = 2542

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KLLSSVKQI 9
            KL+SS KQ+
Sbjct: 2424 KLISSAKQV 2432
>XP_006710367
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLSSVKQI 9
          K+L+ VKQ+
Sbjct: 76 KMLAKVKQV 84
>XP_005270450
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLSSVKQI 9
          K+L+ VKQ+
Sbjct: 76 KMLAKVKQV 84
>XP_005270449
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLSSVKQI 9
          K+L+ VKQ+
Sbjct: 76 KMLAKVKQV 84
>XP_006710366
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLSSVKQI 9
          K+L+ VKQ+
Sbjct: 76 KMLAKVKQV 84
>XP_005270448
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLSSVKQI 9
          K+L+ VKQ+
Sbjct: 76 KMLAKVKQV 84
>NP_006811
          Length = 452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLSSVKQI 9
           K+L+ VKQ+
Sbjct: 334 KMLAKVKQV 342
>NP_057315
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLLSSVKQI 9
           K LSSV+Q+
Sbjct: 469 KNLSSVRQV 477
>XP_005258045
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLLSSVKQI 9
           K LSSV+Q+
Sbjct: 440 KNLSSVRQV 448
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.127    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,300
Number of extensions: 419
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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