Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_036478                                                              17    2528
NP_057637                                                              17    2528
NP_714941                                                              17    2528
NP_714940                                                              17    2528
NP_001180286                                                           17    2528
NP_940943                                                              17    4312
NP_056083                                                              16    5631
XP_005247302                                                           16    5631
NP_003451                                                              16    7355
NP_055785                                                              16    7355
NP_006286                                                              16    7355
NP_001277033                                                           16    7355
NP_001191446                                                           16    7355
NP_001191445                                                           16    7355
XP_005275347                                                           16    7355
XP_005275078                                                           16    7355
XP_005272926                                                           16    7355
XP_005274943                                                           16    7355
XP_005255619                                                           16    7355
XP_005249419                                                           16    7355
XP_005245027                                                           16    7355
NP_065099                                                              15    9605
NP_001026883                                                           15    9605
NP_064504                                                              15    9605
NP_114159                                                              15    9605
NP_078901                                                              15    9605
NP_072045                                                              15    9605
XP_005250558                                                           15    9605
XP_006714396                                                           15    9605
XP_006714395                                                           15    9605
XP_006714394                                                           15    9605
XP_005263325                                                           15    9605
XP_005263324                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1152 LLNANVDS 1159
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1152 LLNANVDS 1159
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1152 LLNANVDS 1159
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1149 LLNANVDS 1156
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1152 LLNANVDS 1159
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLNANVDS 9
            LLNANVDS
Sbjct: 1162 LLNANVDS 1169
>NP_036478
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLLNANVDS 9
           K+LNA++DS
Sbjct: 476 KILNAHMDS 484
>NP_057637
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLLNANVDS 9
           K+LNA++DS
Sbjct: 476 KILNAHMDS 484
>NP_714941
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLLNANVDS 9
           K+LNA++DS
Sbjct: 476 KILNAHMDS 484
>NP_714940
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLLNANVDS 9
           K+LNA++DS
Sbjct: 476 KILNAHMDS 484
>NP_001180286
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KLLNANVDS 9
           K+LNA++DS
Sbjct: 476 KILNAHMDS 484
>NP_940943
          Length = 110

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KLLNANVDS 9
          KL+N N DS
Sbjct: 89 KLINQNCDS 97
>NP_056083
          Length = 2243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KLLNANVDS 9
            K+LN+N +S
Sbjct: 1631 KMLNSNTES 1639
>XP_005247302
          Length = 2248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KLLNANVDS 9
            K+LN+N +S
Sbjct: 1636 KMLNSNTES 1644
>NP_003451
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLNANVDS 9
           LLN NV+S
Sbjct: 473 LLNINVES 480
>NP_055785
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KLLNANVD 8
          K LNAN D
Sbjct: 59 KSLNANTD 66
>NP_006286
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 888 QLLNSNLD 895
>NP_001277033
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLNANVDS 9
           LLN NV+S
Sbjct: 464 LLNINVES 471
>NP_001191446
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KLLNANVD 8
          K LNAN D
Sbjct: 19 KSLNANTD 26
>NP_001191445
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KLLNANVD 8
          K LNAN D
Sbjct: 15 KSLNANTD 22
>XP_005275347
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 889 QLLNSNLD 896
>XP_005275078
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 889 QLLNSNLD 896
>XP_005272926
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 889 QLLNSNLD 896
>XP_005274943
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 889 QLLNSNLD 896
>XP_005255619
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLNANVDS 9
           LLN NV+S
Sbjct: 562 LLNINVES 569
>XP_005249419
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLNANVD 8
           +LLN+N+D
Sbjct: 889 QLLNSNLD 896
>XP_005245027
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  KLLNANVD 8
          K LNAN D
Sbjct: 59 KSLNANTD 66
>NP_065099
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KLLNANVD 8
           KLLN N D
Sbjct: 372 KLLNDNYD 379
>NP_001026883
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           K+L AN+D
Sbjct: 194 KILEANMD 201
>NP_064504
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLLNANVDS 9
           K  N+NVDS
Sbjct: 627 KRKNSNVDS 635
>NP_114159
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 185 KLINSNSD 192
>NP_078901
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLLNANVDS 9
           K  N+NVDS
Sbjct: 627 KRKNSNVDS 635
>NP_072045
          Length = 152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  KLLNANVD 8
          ++LN N+D
Sbjct: 14 RVLNTNID 21
>XP_005250558
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLLNANVDS 9
           K  N+NVDS
Sbjct: 749 KRKNSNVDS 757
>XP_006714396
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 185 KLINSNSD 192
>XP_006714395
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 248 KLINSNSD 255
>XP_006714394
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 349 KLINSNSD 356
>XP_005263325
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 349 KLINSNSD 356
>XP_005263324
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLLNANVD 8
           KL+N+N D
Sbjct: 349 KLINSNSD 356
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.122    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 406,307
Number of extensions: 671
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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