Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001013433                                                           20     390
NP_060785                                                              20     390
NP_361014                                                              20     390
XP_005247844                                                           17    3301
NP_079094                                                              17    3301
NP_938143                                                              17    3301
NP_006028                                                              17    4312
NP_997634                                                              17    4312
NP_001268                                                              17    4312
NP_056216                                                              17    4312
NP_001091886                                                           17    4312
NP_001273385                                                           17    4312
XP_006719521                                                           17    4312
XP_006719520                                                           17    4312
XP_006719519                                                           17    4312
XP_005269025                                                           17    4312
XP_006719518                                                           17    4312
XP_006719517                                                           17    4312
XP_005249342                                                           17    4312
XP_006712943                                                           17    4312
XP_006712942                                                           17    4312
XP_006712941                                                           17    4312
XP_006712940                                                           17    4312
NP_056297                                                              17    4312
NP_065194                                                              16    5631
NP_055751                                                              16    5631
NP_478056                                                              16    5631
NP_848512                                                              16    5631
NP_848510                                                              16    5631
NP_848638                                                              16    5631
NP_115618                                                              16    5631
XP_005277842                                                           16    5631
XP_006715865                                                           16    5631
XP_006713726                                                           16    5631
NP_004563                                                              16    7355
NP_001005242                                                           16    7355
NP_659486                                                              16    7355
NP_079023                                                              15    9605
NP_001265092                                                           15    9605
NP_001265091                                                           15    9605
NP_005725                                                              15    9605
NP_001041665                                                           15    9605
NP_001137247                                                           15    9605
NP_056158                                                              15    9605
NP_005779                                                              15    9605
NP_003326                                                              15    9605
NP_001248770                                                           15    9605
NP_059984                                                              15    9605
NP_001138639                                                           15    9605
NP_001138638                                                           15    9605
XP_006724893                                                           15    9605
XP_005274763                                                           15    9605
XP_006724892                                                           15    9605
XP_005274762                                                           15    9605
XP_005255642                                                           15    9605
XP_005252787                                                           15    9605
XP_006718183                                                           15    9605
XP_005252786                                                           15    9605
XP_005265487                                                           15    9605
XP_006713384                                                           15    9605
NP_001098719                                                           15    9605
NP_001098718                                                           15    9605
NP_079056                                                              15    9605
NP_699207                                                              15    9605
>NP_001013433
          Length = 589

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           KLL+LDFDV
Sbjct: 578 KLLVLDFDV 586
>NP_060785
          Length = 627

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           KLL+LDFDV
Sbjct: 616 KLLVLDFDV 624
>NP_361014
          Length = 707

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           KLL+LDFDV
Sbjct: 696 KLLVLDFDV 704
>XP_005247844
          Length = 348

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          KLLL D+D
Sbjct: 43 KLLLFDYD 50
>NP_079094
          Length = 404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLLLLDFD 8
           KLLL D+D
Sbjct: 99  KLLLFDYD 106
>NP_938143
          Length = 348

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          KLLL D+D
Sbjct: 43 KLLLFDYD 50
>NP_006028
          Length = 1084

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 833 KILIVDWDV 841
>NP_997634
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLLLDFD 8
           KL+L+DF+
Sbjct: 307 KLMLIDFE 314
>NP_001268
          Length = 457

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLLLLDFD 8
           KL+L+DF+
Sbjct: 325 KLMLIDFE 332
>NP_056216
          Length = 991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 739 KILIVDWDV 747
>NP_001091886
          Length = 954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 702 KILIVDWDV 710
>NP_001273385
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLLLDFD 8
          LLLLD+D
Sbjct: 75 LLLLDYD 81
>XP_006719521
          Length = 944

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 692 KILIVDWDV 700
>XP_006719520
          Length = 950

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 698 KILIVDWDV 706
>XP_006719519
          Length = 968

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 716 KILIVDWDV 724
>XP_005269025
          Length = 974

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 722 KILIVDWDV 730
>XP_006719518
          Length = 981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 729 KILIVDWDV 737
>XP_006719517
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 753 KILIVDWDV 761
>XP_005249342
          Length = 694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLLLDFD 8
          LLLLD+D
Sbjct: 75 LLLLDYD 81
>XP_006712943
          Length = 1062

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 811 KILIVDWDV 819
>XP_006712942
          Length = 1062

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 811 KILIVDWDV 819
>XP_006712941
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 838 KILIVDWDV 846
>XP_006712940
          Length = 1108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KLLLLDFDV 9
           K+L++D+DV
Sbjct: 857 KILIVDWDV 865
>NP_056297
          Length = 686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLLLDFD 8
          LLLLD+D
Sbjct: 75 LLLLDYD 81
>NP_065194
          Length = 1819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KLLLLDFDV 9
          K+L+L FD+
Sbjct: 69 KILMLSFDL 77
>NP_055751
          Length = 453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          KLLL+ FD
Sbjct: 27 KLLLVSFD 34
>NP_478056
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+L++D DV
Sbjct: 813 KILIVDLDV 821
>NP_848512
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+L++D DV
Sbjct: 816 KILIVDLDV 824
>NP_848510
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+L++D DV
Sbjct: 813 KILIVDLDV 821
>NP_848638
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          KLLL+ FD
Sbjct: 32 KLLLVSFD 39
>NP_115618
          Length = 1896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLLLD+
Sbjct: 116 KLLLLDY 122
>XP_005277842
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLLLLDFD 8
           KLLL+ FD
Sbjct: 105 KLLLVSFD 112
>XP_006715865
          Length = 1088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+L++D DV
Sbjct: 835 KILIVDLDV 843
>XP_006713726
          Length = 1910

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLLLD+
Sbjct: 134 KLLLLDY 140
>NP_004563
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LLDFDV 9
           LLDFD+
Sbjct: 549 LLDFDI 554
>NP_001005242
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LLDFDV 9
           LLDFD+
Sbjct: 505 LLDFDI 510
>NP_659486
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLLLLDFD 8
           KLL+LD D
Sbjct: 138 KLLVLDVD 145
>NP_079023
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLLLDF 7
           LLLLDF
Sbjct: 280 LLLLDF 285
>NP_001265092
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>NP_001265091
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>NP_005725
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>NP_001041665
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>NP_001137247
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          K+L+LD D
Sbjct: 62 KILVLDLD 69
>NP_056158
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KLLLLDFD 8
          K+L+LD D
Sbjct: 62 KILVLDLD 69
>NP_005779
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLDFDV 9
           LLL FDV
Sbjct: 129 LLLQFDV 135
>NP_003326
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLDFDV 9
           LLLDF V
Sbjct: 115 LLLDFQV 121
>NP_001248770
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           +LLL+DF
Sbjct: 735 RLLLMDF 741
>NP_059984
          Length = 1871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLL+D+
Sbjct: 98  KLLLIDY 104
>NP_001138639
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLLDFDV 9
          LLL FDV
Sbjct: 52 LLLQFDV 58
>NP_001138638
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLLDFDV 9
          LLL FDV
Sbjct: 67 LLLQFDV 73
>XP_006724893
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLL+D+
Sbjct: 98  KLLLIDY 104
>XP_005274763
          Length = 1789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KLLLLDF 7
          KLLL+D+
Sbjct: 16 KLLLIDY 22
>XP_006724892
          Length = 1841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLL+D+
Sbjct: 98  KLLLIDY 104
>XP_005274762
          Length = 1853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           KLLL+D+
Sbjct: 98  KLLLIDY 104
>XP_005255642
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           +LLL+DF
Sbjct: 376 RLLLMDF 382
>XP_005252787
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLDFDV 9
           LLL FDV
Sbjct: 96  LLLQFDV 102
>XP_006718183
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>XP_005252786
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLLLLDFDV 9
           K+LL+D D+
Sbjct: 504 KMLLIDADL 512
>XP_005265487
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLDFDV 9
           LLLDF V
Sbjct: 115 LLLDFQV 121
>XP_006713384
          Length = 1005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLDFDV 9
           LLLDF V
Sbjct: 115 LLLDFQV 121
>NP_001098719
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           +LLL+DF
Sbjct: 735 RLLLMDF 741
>NP_001098718
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           +LLL+DF
Sbjct: 735 RLLLMDF 741
>NP_079056
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KLLLLDF 7
           +LLL+DF
Sbjct: 489 RLLLMDF 495
>NP_699207
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLLLDFD 8
           LLL+DF+
Sbjct: 403 LLLIDFE 409
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.166    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,557
Number of extensions: 732
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package