Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           20     299
NP_858045                                                              20     299
NP_006525                                                              20     299
NP_001167559                                                           20     299
NP_919263                                                              18    1482
XP_006720118                                                           18    1482
XP_006720117                                                           18    1482
XP_006720116                                                           18    1482
XP_005267417                                                           18    1482
NP_078837                                                              17    2528
NP_733751                                                              17    2528
XP_005266580                                                           17    2528
XP_005266579                                                           17    2528
XP_006719929                                                           17    2528
XP_006716142                                                           17    2528
XP_005250088                                                           17    2528
XP_006716141                                                           17    2528
XP_005250085                                                           17    2528
XP_006716140                                                           17    2528
XP_005250084                                                           17    2528
XP_005250083                                                           17    2528
XP_005250082                                                           17    2528
NP_000954                                                              17    4312
NP_078858                                                              17    4312
NP_001278232                                                           17    4312
NP_001278214                                                           17    4312
NP_001860                                                              17    4312
NP_003292                                                              16    5631
NP_001161707                                                           16    5631
NP_055514                                                              16    7355
NP_005119                                                              16    7355
XP_006724131                                                           16    7355
XP_005255769                                                           16    7355
XP_005255768                                                           16    7355
XP_005255767                                                           16    7355
NP_001276627                                                           15    9605
NP_001122087                                                           15    9605
NP_062455                                                              15    9605
NP_001122088                                                           15    9605
NP_997244                                                              15    9605
NP_612388                                                              15    9605
NP_003081                                                              15    9605
NP_001140198                                                           15    9605
NP_065976                                                              15    9605
NP_055568                                                              15    9605
NP_775105                                                              15    9605
NP_689484                                                              15    9605
NP_631938                                                              15    9605
NP_006687                                                              15    9605
NP_001036148                                                           15    9605
NP_001157798                                                           15    9605
XP_005271905                                                           15    9605
XP_005271904                                                           15    9605
XP_005271903                                                           15    9605
XP_005273742                                                           15    9605
XP_006715506                                                           15    9605
XP_006715505                                                           15    9605
XP_006715504                                                           15    9605
XP_006715503                                                           15    9605
XP_006715502                                                           15    9605
XP_005271918                                                           15    9605
XP_006714588                                                           15    9605
XP_005271917                                                           15    9605
XP_005271912                                                           15    9605
XP_005271916                                                           15    9605
XP_005271914                                                           15    9605
XP_006714587                                                           15    9605
XP_005271913                                                           15    9605
XP_005263127                                                           15    9605
XP_005265245                                                           15    9605
XP_005265244                                                           15    9605
XP_005265243                                                           15    9605
NP_061908                                                              15    9605
>NP_001167558
          Length = 1423

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KLF NPVTN
Sbjct: 350 KLFRNPVTN 358
>NP_858045
          Length = 1424

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KLF NPVTN
Sbjct: 350 KLFRNPVTN 358
>NP_006525
          Length = 1420

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KLF NPVTN
Sbjct: 350 KLFRNPVTN 358
>NP_001167559
          Length = 1415

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KLF NPVTN
Sbjct: 360 KLFRNPVTN 368
>NP_919263
          Length = 488

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLFLNPV 7
           KLFLNP+
Sbjct: 336 KLFLNPI 342
>XP_006720118
          Length = 248

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLFLNPV 7
           KLFLNP+
Sbjct: 96  KLFLNPI 102
>XP_006720117
          Length = 396

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLFLNPV 7
           KLFLNP+
Sbjct: 244 KLFLNPI 250
>XP_006720116
          Length = 396

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLFLNPV 7
           KLFLNP+
Sbjct: 244 KLFLNPI 250
>XP_005267417
          Length = 471

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KLFLNPV 7
           KLFLNP+
Sbjct: 319 KLFLNPI 325
>NP_078837
          Length = 864

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KL+ NP+TN
Sbjct: 567 KLYDNPLTN 575
>NP_733751
          Length = 4911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2189 LFVTPVTN 2196
>XP_005266580
          Length = 452

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KL+ NP+TN
Sbjct: 155 KLYDNPLTN 163
>XP_005266579
          Length = 653

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KL+ NP+TN
Sbjct: 567 KLYDNPLTN 575
>XP_006719929
          Length = 804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLFLNPVTN 9
           KL+ NP+TN
Sbjct: 507 KLYDNPLTN 515
>XP_006716142
          Length = 4927

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_005250088
          Length = 4928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_006716141
          Length = 4959

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_005250085
          Length = 4979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_006716140
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_005250084
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>XP_005250083
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2205 LFVTPVTN 2212
>XP_005250082
          Length = 4983

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFLNPVTN 9
            LF+ PVTN
Sbjct: 2206 LFVTPVTN 2213
>NP_000954
          Length = 604

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KLFLNPVTN 9
          KLFL P  N
Sbjct: 64 KLFLKPTPN 72
>NP_078858
          Length = 4981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FLNPVT 8
            FLNP+T
Sbjct: 1890 FLNPIT 1895
>NP_001278232
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FLNPVT 8
            FLNP+T
Sbjct: 1890 FLNPIT 1895
>NP_001278214
          Length = 4982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FLNPVT 8
            FLNP+T
Sbjct: 1890 FLNPIT 1895
>NP_001860
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVTN
Sbjct: 215 IFLLPVTN 222
>NP_003292
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LFLNPV 7
           LFLNP+
Sbjct: 218 LFLNPI 223
>NP_001161707
          Length = 2139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LFLNPVTN 9
           LFL PV N
Sbjct: 820 LFLQPVDN 827
>NP_055514
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KLFLNPV 7
            K FLNPV
Sbjct: 1564 KEFLNPV 1570
>NP_005119
          Length = 2298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FLNPVT 8
            FLNP+T
Sbjct: 1675 FLNPLT 1680
>XP_006724131
          Length = 2298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FLNPVT 8
            FLNP+T
Sbjct: 1675 FLNPLT 1680
>XP_005255769
          Length = 1808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KLFLNPV 7
            K FLNPV
Sbjct: 1564 KEFLNPV 1570
>XP_005255768
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KLFLNPV 7
            K FLNPV
Sbjct: 1564 KEFLNPV 1570
>XP_005255767
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KLFLNPV 7
            K FLNPV
Sbjct: 1564 KEFLNPV 1570
>NP_001276627
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 473 FLNPTT 478
>NP_001122087
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 499 FLNPTT 504
>NP_062455
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 467 FLNPTT 472
>NP_001122088
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 473 FLNPTT 478
>NP_997244
          Length = 3169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           L+L+PV N
Sbjct: 820 LYLHPVDN 827
>NP_612388
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LFLNPVTN 9
          L+L PVT+
Sbjct: 17 LYLTPVTS 24
>NP_003081
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NPVTN 9
           NPVTN
Sbjct: 123 NPVTN 127
>NP_001140198
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LFLNPVTN 9
          L+L PVT+
Sbjct: 17 LYLTPVTS 24
>NP_065976
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KLFLNPVTN 9
           K FL+P T+
Sbjct: 232 KTFLSPATS 240
>NP_055568
          Length = 1282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FLNPVTN 9
            F NPVT+
Sbjct: 1109 FYNPVTS 1115
>NP_775105
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>NP_689484
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           +LF  PVT
Sbjct: 484 RLFFEPVT 491
>NP_631938
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 731 VFLQPVTD 738
>NP_006687
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 804 VFLQPVTD 811
>NP_001036148
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>NP_001157798
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 734 VFLQPVTD 741
>XP_005271905
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FLNPVTN 9
            F NPVT+
Sbjct: 1046 FYNPVTS 1052
>XP_005271904
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FLNPVTN 9
            F NPVT+
Sbjct: 1046 FYNPVTS 1052
>XP_005271903
          Length = 1282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FLNPVTN 9
            F NPVT+
Sbjct: 1109 FYNPVTS 1115
>XP_005273742
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           +LF  PVT
Sbjct: 473 RLFFEPVT 480
>XP_006715506
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>XP_006715505
          Length = 1673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>XP_006715504
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>XP_006715503
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>XP_006715502
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KLFLNPVT 8
           KL+ NP T
Sbjct: 345 KLYYNPYT 352
>XP_005271918
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 731 VFLQPVTD 738
>XP_006714588
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 765 VFLQPVTD 772
>XP_005271917
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 804 VFLQPVTD 811
>XP_005271912
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 804 VFLQPVTD 811
>XP_005271916
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 661 VFLQPVTD 668
>XP_005271914
          Length = 1238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 734 VFLQPVTD 741
>XP_006714587
          Length = 1269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 765 VFLQPVTD 772
>XP_005271913
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFLNPVTN 9
           +FL PVT+
Sbjct: 804 VFLQPVTD 811
>XP_005263127
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    FLNPVTN 9
            F NP TN
Sbjct: 1061 FQNPTTN 1067
>XP_005265245
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 479 FLNPTT 484
>XP_005265244
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 499 FLNPTT 504
>XP_005265243
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FLNPVT 8
           FLNP T
Sbjct: 499 FLNPTT 504
>NP_061908
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    FLNPVTN 9
            F NP TN
Sbjct: 1062 FQNPTTN 1068
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.141    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 736,793
Number of extensions: 980
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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