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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     299
NP_001035957                                                           20     299
XP_006721991                                                           20     299
XP_006721990                                                           20     299
XP_006721989                                                           20     299
XP_005258041                                                           20     299
XP_006721988                                                           20     299
XP_006721987                                                           20     299
XP_006721986                                                           20     299
XP_005258040                                                           20     299
XP_006721985                                                           20     299
NP_777637                                                              17    4312
NP_001154840                                                           17    4312
XP_006724298                                                           17    4312
XP_006724297                                                           17    4312
XP_006724296                                                           17    4312
XP_005261640                                                           17    4312
XP_006724295                                                           17    4312
XP_006724294                                                           17    4312
NP_005496                                                              16    5631
NP_001076428                                                           16    5631
NP_996809                                                              16    7355
NP_065184                                                              16    7355
NP_689590                                                              16    7355
NP_001171434                                                           15    9605
NP_112492                                                              15    9605
NP_002422                                                              15    9605
XP_005267745                                                           15    9605
XP_005267744                                                           15    9605

>NP_000258
          Length = 2818

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 686 KLEVALYMF 694



>NP_001035957
          Length = 2839

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 686 KLEVALYMF 694



>XP_006721991
          Length = 1632

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>XP_006721990
          Length = 2823

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>XP_006721989
          Length = 2823

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>XP_005258041
          Length = 2836

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 686 KLEVALYMF 694



>XP_006721988
          Length = 2846

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>XP_006721987
          Length = 2849

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>XP_006721986
          Length = 2854

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 683 KLEVALYMF 691



>XP_005258040
          Length = 2857

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 686 KLEVALYMF 694



>XP_006721985
          Length = 2867

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLEMALYMF 9
           KLE+ALYMF
Sbjct: 696 KLEVALYMF 704



>NP_777637
          Length = 406

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 145 KIEMALMVF 153



>NP_001154840
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 145 KIEMALMVF 153



>XP_006724298
          Length = 352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLEMALYMF 9
          K+EMAL +F
Sbjct: 91 KIEMALMVF 99



>XP_006724297
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 92  KIEMALMVF 100



>XP_006724296
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 92  KIEMALMVF 100



>XP_005261640
          Length = 407

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 146 KIEMALMVF 154



>XP_006724295
          Length = 465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 204 KIEMALMVF 212



>XP_006724294
          Length = 466

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           K+EMAL +F
Sbjct: 205 KIEMALMVF 213



>NP_005496
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLEMALYM 8
           KL+++LYM
Sbjct: 387 KLQLSLYM 394



>NP_001076428
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLEMALYM 8
           KL+++LYM
Sbjct: 387 KLQLSLYM 394



>NP_996809
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           +LE+A+Y F
Sbjct: 383 RLEVAMYPF 391



>NP_065184
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLEMALYMF 9
           +LE+A+Y F
Sbjct: 417 RLEVAMYPF 425



>NP_689590
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLEMALYM 8
           KLE ALY+
Sbjct: 480 KLENALYL 487



>NP_001171434
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLEMALYMF 9
           KLE ALY +
Sbjct: 198 KLEEALYEY 206



>NP_112492
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LEMALYM 8
           LE+ALY+
Sbjct: 456 LELALYL 462



>NP_002422
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLEMALYMF 9
           KLE ALY +
Sbjct: 240 KLEEALYEY 248



>XP_005267745
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLEMALYMF 9
           KLE ALY +
Sbjct: 240 KLEEALYEY 248



>XP_005267744
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLEMALYMF 9
           KLE ALY +
Sbjct: 240 KLEEALYEY 248



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.146    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 369,769
Number of extensions: 366
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)