Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     869
NP_000242                                                              19     869
XP_005264389                                                           19     869
NP_006217                                                              17    3301
XP_005246701                                                           17    3301
XP_005246700                                                           17    3301
NP_598328                                                              17    4312
NP_003169                                                              17    4312
NP_001129246                                                           17    4312
XP_006713376                                                           17    4312
XP_006713375                                                           17    4312
XP_006713374                                                           17    4312
NP_003481                                                              17    4312
NP_598344                                                              17    4312
NP_631938                                                              16    5631
NP_006687                                                              16    5631
NP_001157798                                                           16    5631
XP_005271922                                                           16    5631
XP_005271921                                                           16    5631
XP_005271918                                                           16    5631
XP_006714588                                                           16    5631
XP_005271917                                                           16    5631
XP_005271912                                                           16    5631
XP_005271916                                                           16    5631
XP_005271914                                                           16    5631
XP_006714587                                                           16    5631
XP_005271913                                                           16    5631
NP_071445                                                              16    7355
XP_006721306                                                           16    7355
XP_006721305                                                           16    7355
XP_005256141                                                           16    7355
NP_524144                                                              15    9605
NP_001164509                                                           15    9605
NP_004034                                                              15    9605
NP_443148                                                              15    9605
XP_006721725                                                           15    9605
XP_005257064                                                           15    9605
XP_006721724                                                           15    9605
XP_006721723                                                           15    9605
NP_001164510                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLDIAAVKA 9
           KLDIAAV+A
Sbjct: 235 KLDIAAVRA 243
>NP_000242
          Length = 934

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLDIAAVKA 9
           KLDIAAV+A
Sbjct: 301 KLDIAAVRA 309
>XP_005264389
          Length = 921

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KLDIAAVKA 9
           KLDIAAV+A
Sbjct: 301 KLDIAAVRA 309
>NP_006217
          Length = 1095

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KLDIAAVK 8
           KLDI+A+K
Sbjct: 157 KLDISAIK 164
>XP_005246701
          Length = 1016

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KLDIAAVK 8
          KLDI+A+K
Sbjct: 78 KLDISAIK 85
>XP_005246700
          Length = 1021

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KLDIAAVK 8
          KLDI+A+K
Sbjct: 83 KLDISAIK 90
>NP_598328
          Length = 582

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 367 LDICAVKA 374
>NP_003169
          Length = 478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 367 LDICAVKA 374
>NP_001129246
          Length = 579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 345 LDICAVKA 352
>XP_006713376
          Length = 325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 110 LDICAVKA 117
>XP_006713375
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 206 LDICAVKA 213
>XP_006713374
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 367 LDICAVKA 374
>NP_003481
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 346 LDICAVKA 353
>NP_598344
          Length = 444

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LDI AVKA
Sbjct: 346 LDICAVKA 353
>NP_631938
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 434 LDVAAVEA 441
>NP_006687
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>NP_001157798
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 437 LDVAAVEA 444
>XP_005271922
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271921
          Length = 713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271918
          Length = 878

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 434 LDVAAVEA 441
>XP_006714588
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 468 LDVAAVEA 475
>XP_005271917
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271912
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271916
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 364 LDVAAVEA 371
>XP_005271914
          Length = 1238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 437 LDVAAVEA 444
>XP_006714587
          Length = 1269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 468 LDVAAVEA 475
>XP_005271913
          Length = 1293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LDIAAVKA 9
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>NP_071445
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LD+A VKA
Sbjct: 185 LDLATVKA 192
>XP_006721306
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>XP_006721305
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>XP_005256141
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LDIAAVKA 9
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>NP_524144
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  KLDIAAVK 8
          K+D++A+K
Sbjct: 37 KIDLSAIK 44
>NP_001164509
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LDIAAVKA 9
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
>NP_004034
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LDIAAVKA 9
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
>NP_443148
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DIAAVKA 9
           DIA+VKA
Sbjct: 622 DIASVKA 628
>XP_006721725
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DIAAVKA 9
           DIA+VKA
Sbjct: 556 DIASVKA 562
>XP_005257064
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DIAAVKA 9
           DIA+VKA
Sbjct: 622 DIASVKA 628
>XP_006721724
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DIAAVKA 9
           DIA+VKA
Sbjct: 623 DIASVKA 629
>XP_006721723
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DIAAVKA 9
           DIA+VKA
Sbjct: 623 DIASVKA 629
>NP_001164510
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LDIAAVKA 9
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.128    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 294,125
Number of extensions: 232
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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