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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1482
NP_001243765                                                           16    5631
NP_001243766                                                           16    5631
NP_078914                                                              16    5631
NP_001243764                                                           16    5631
XP_005247827                                                           16    5631
XP_006713807                                                           16    5631
XP_005247826                                                           16    5631
NP_115518                                                              16    7355
NP_112593                                                              16    7355
NP_001171561                                                           16    7355
NP_001171560                                                           16    7355
XP_006722617                                                           16    7355
XP_005258414                                                           16    7355
XP_006722395                                                           16    7355
XP_006722394                                                           16    7355
XP_005258167                                                           16    7355
XP_006722393                                                           16    7355
XP_006722392                                                           16    7355
XP_006722391                                                           16    7355
XP_006722390                                                           16    7355
XP_005258166                                                           16    7355
XP_006722389                                                           16    7355
XP_005258165                                                           16    7355
XP_005258164                                                           16    7355
XP_006714918                                                           16    7355
NP_872400                                                              16    7355
NP_056138                                                              15    9605

>NP_115927
          Length = 1321

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           KKS VTAEL
Sbjct: 845 KKSPVTAEL 853



>NP_001243765
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 131 SSVTAEL 137



>NP_001243766
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 114 SSVTAEL 120



>NP_078914
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 237 SSVTAEL 243



>NP_001243764
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 249 SSVTAEL 255



>XP_005247827
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 114 SSVTAEL 120



>XP_006713807
          Length = 329

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 151 SSVTAEL 157



>XP_005247826
          Length = 329

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSVTAEL 9
           SSVTAEL
Sbjct: 151 SSVTAEL 157



>NP_115518
          Length = 2537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 1062 RKSDITSEL 1070



>NP_112593
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KKSSVTAE 8
          KKSS TAE
Sbjct: 19 KKSSDTAE 26



>NP_001171561
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           KKS+V AE+
Sbjct: 92  KKSTVKAEI 100



>NP_001171560
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           KKS+V AE+
Sbjct: 92  KKSTVKAEI 100



>XP_006722617
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KKSSVTAE 8
          KKSS TAE
Sbjct: 91 KKSSDTAE 98



>XP_005258414
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KKSSVTAE 8
           KKSS TAE
Sbjct: 117 KKSSDTAE 124



>XP_006722395
          Length = 1419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 1062 RKSDITSEL 1070



>XP_006722394
          Length = 1845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           +KS +T+EL
Sbjct: 369 RKSDITSEL 377



>XP_005258167
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           +KS +T+EL
Sbjct: 380 RKSDITSEL 388



>XP_006722393
          Length = 2199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           +KS +T+EL
Sbjct: 723 RKSDITSEL 731



>XP_006722392
          Length = 2444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           +KS +T+EL
Sbjct: 968 RKSDITSEL 976



>XP_006722391
          Length = 2448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           +KS +T+EL
Sbjct: 972 RKSDITSEL 980



>XP_006722390
          Length = 2467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 992  RKSDITSEL 1000



>XP_005258166
          Length = 2468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 992  RKSDITSEL 1000



>XP_006722389
          Length = 2506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 1062 RKSDITSEL 1070



>XP_005258165
          Length = 2534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 1058 RKSDITSEL 1066



>XP_005258164
          Length = 2538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKSSVTAEL 9
            +KS +T+EL
Sbjct: 1062 RKSDITSEL 1070



>XP_006714918
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           KKS+V AE+
Sbjct: 92  KKSTVKAEI 100



>NP_872400
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKSSVTAEL 9
           KKS+V AE+
Sbjct: 92  KKSTVKAEI 100



>NP_056138
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KKSSVTAE 8
           +KSSVT E
Sbjct: 787 RKSSVTEE 794



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285    0.100    0.212 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 248,051
Number of extensions: 245
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)