Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              17    2528
NP_001129225                                                           17    4312
NP_001129224                                                           17    4312
NP_009196                                                              17    4312
NP_001071643                                                           16    5631
NP_001071644                                                           16    5631
NP_001071645                                                           16    5631
NP_001071642                                                           16    5631
NP_004946                                                              16    5631
NP_004645                                                              16    5631
NP_001034680                                                           16    5631
NP_001034679                                                           16    5631
NP_570969                                                              16    5631
NP_056127                                                              16    5631
NP_001073005                                                           16    5631
XP_005272733                                                           16    5631
XP_005272732                                                           16    5631
XP_005248939                                                           16    5631
XP_005248938                                                           16    5631
XP_005248936                                                           16    5631
XP_005248937                                                           16    5631
XP_005248935                                                           16    5631
XP_005248933                                                           16    5631
XP_005248932                                                           16    5631
XP_006714407                                                           16    5631
XP_006714406                                                           16    5631
XP_006714405                                                           16    5631
XP_005263349                                                           16    5631
XP_005263348                                                           16    5631
XP_005263347                                                           16    5631
XP_005263346                                                           16    5631
XP_005263345                                                           16    5631
XP_005263344                                                           16    5631
XP_005263343                                                           16    5631
XP_005263342                                                           16    5631
XP_005263341                                                           16    5631
XP_005263340                                                           16    5631
XP_005263339                                                           16    5631
NP_803235                                                              16    5631
NP_055887                                                              16    7355
>NP_115927
          Length = 1321

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KKSLVTAEL 9
           KKS VTAEL
Sbjct: 845 KKSPVTAEL 853
>NP_001129225
          Length = 601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   KKSLVTA 7
           KKSLVTA
Sbjct: 280 KKSLVTA 286
>NP_001129224
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   KKSLVTA 7
           KKSLVTA
Sbjct: 323 KKSLVTA 329
>NP_009196
          Length = 644

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   KKSLVTA 7
           KKSLVTA
Sbjct: 323 KKSLVTA 329
>NP_001071643
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>NP_001071644
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>NP_001071645
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>NP_001071642
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>NP_004946
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>NP_004645
          Length = 2555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KSL+TA+L
Sbjct: 959 KSLITAKL 966
>NP_001034680
          Length = 2554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KSL+TA+L
Sbjct: 958 KSLITAKL 965
>NP_001034679
          Length = 2570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KSL+TA+L
Sbjct: 958 KSLITAKL 965
>NP_570969
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KSLVTAEL 9
           KSLV AEL
Sbjct: 199 KSLVAAEL 206
>NP_056127
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>NP_001073005
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KS+VTAE+
Sbjct: 136 KSIVTAEV 143
>XP_005272733
          Length = 2559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KSL+TA+L
Sbjct: 963 KSLITAKL 970
>XP_005272732
          Length = 2575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KSL+TA+L
Sbjct: 963 KSLITAKL 970
>XP_005248939
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>XP_005248938
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>XP_005248936
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>XP_005248937
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>XP_005248935
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 50 SLVTAEL 56
>XP_005248933
          Length = 499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLVTAEL 9
          SLVTAEL
Sbjct: 93 SLVTAEL 99
>XP_005248932
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SLVTAEL 9
           SLVTAEL
Sbjct: 129 SLVTAEL 135
>XP_006714407
          Length = 5004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2761 KRSLVTSE 2768
>XP_006714406
          Length = 3680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_006714405
          Length = 4103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 1839 KRSLVTSE 1846
>XP_005263349
          Length = 4410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2146 KRSLVTSE 2153
>XP_005263348
          Length = 4443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2179 KRSLVTSE 2186
>XP_005263347
          Length = 4640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263346
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2719 KRSLVTSE 2726
>XP_005263345
          Length = 4991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263344
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263343
          Length = 5009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263342
          Length = 5025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2761 KRSLVTSE 2768
>XP_005263341
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263340
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>XP_005263339
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KKSLVTAE 8
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769
>NP_803235
          Length = 130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSLVTAEL 9
           KS+VTAE+
Sbjct: 108 KSIVTAEV 115
>NP_055887
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KSLVTAEL 9
            +S+VTAEL
Sbjct: 1026 QSMVTAEL 1033
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.116    0.256 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 263,530
Number of extensions: 249
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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