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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              19     869
XP_005271924                                                           19     869
XP_005271923                                                           19     869
XP_006717206                                                           18    1135
XP_005252108                                                           18    1135
NP_005383                                                              18    1135
NP_001171313                                                           17    4312
NP_003130                                                              17    4312
NP_001191676                                                           16    5631
NP_002904                                                              16    5631
NP_803193                                                              16    7355
NP_001185844                                                           16    7355
XP_006719223                                                           16    7355
XP_006719222                                                           16    7355
XP_005253568                                                           16    7355
XP_005253567                                                           16    7355
XP_005253566                                                           16    7355
XP_005253565                                                           16    7355
XP_005253564                                                           16    7355
XP_005253563                                                           16    7355
XP_005253562                                                           16    7355
NP_056052                                                              15    9605
NP_055520                                                              15    9605
NP_443143                                                              15    9605
XP_006722442                                                           15    9605
XP_006716252                                                           15    9605
XP_006716251                                                           15    9605

>NP_001261
          Length = 1710

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KKNKATKSI 9
            KKNKA KSI
Sbjct: 1337 KKNKAMKSI 1345



>XP_005271924
          Length = 1710

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KKNKATKSI 9
            KKNKA KSI
Sbjct: 1337 KKNKAMKSI 1345



>XP_005271923
          Length = 1798

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KKNKATKSI 9
            KKNKA KSI
Sbjct: 1337 KKNKAMKSI 1345



>XP_006717206
          Length = 1062

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK KATKS+
Sbjct: 528 KKGKATKSV 536



>XP_005252108
          Length = 1097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK KATKS+
Sbjct: 563 KKGKATKSV 571



>NP_005383
          Length = 1096

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK KATKS+
Sbjct: 563 KKGKATKSV 571



>NP_001171313
          Length = 610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KKNKATKS 8
           K NK+TKS
Sbjct: 199 KSNKSTKS 206



>NP_003130
          Length = 638

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KKNKATKS 8
           K NK+TKS
Sbjct: 227 KSNKSTKS 234



>NP_001191676
          Length = 1148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KKNKATKS 8
          KKN+ TKS
Sbjct: 22 KKNEKTKS 29



>NP_002904
          Length = 1147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KKNKATKS 8
          KKN+ TKS
Sbjct: 22 KKNEKTKS 29



>NP_803193
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>NP_001185844
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KKNKATKSI 9
          KK K+TKS+
Sbjct: 73 KKLKSTKSL 81



>XP_006719223
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_006719222
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KKNKATKSI 9
          KK K+TKS+
Sbjct: 73 KKLKSTKSL 81



>XP_005253568
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253567
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253566
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253565
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253564
          Length = 1033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253563
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>XP_005253562
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKNKATKSI 9
           KK K+TKS+
Sbjct: 226 KKLKSTKSL 234



>NP_056052
          Length = 1354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KNKATKSI 9
            KN +TKS+
Sbjct: 1161 KNSSTKSL 1168



>NP_055520
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKNKATKSI 9
           KKN + KS+
Sbjct: 863 KKNSSEKSV 871



>NP_443143
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  NKATKSI 9
          +KATKSI
Sbjct: 77 DKATKSI 83



>XP_006722442
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  NKATKSI 9
          +KATKSI
Sbjct: 77 DKATKSI 83



>XP_006716252
          Length = 1937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKNKATKSI 9
           KKN + KS+
Sbjct: 863 KKNSSEKSV 871



>XP_006716251
          Length = 1975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKNKATKSI 9
           KKN + KS+
Sbjct: 863 KKNSSEKSV 871



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.104    0.236 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,893
Number of extensions: 492
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)