Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_066958                                                              16    5631
NP_001006933                                                           16    5631
NP_002944                                                              16    5631
NP_001006666                                                           16    5631
XP_005267149                                                           16    5631
XP_006715612                                                           16    5631
XP_005246023                                                           16    5631
NP_872198                                                              16    7355
NP_055520                                                              16    7355
NP_008937                                                              16    7355
NP_004746                                                              16    7355
NP_064710                                                              16    7355
XP_005272668                                                           16    7355
XP_005272667                                                           16    7355
XP_006724596                                                           16    7355
XP_005255493                                                           16    7355
XP_006721128                                                           16    7355
XP_005255492                                                           16    7355
XP_005251100                                                           16    7355
XP_006716252                                                           16    7355
XP_006716251                                                           16    7355
NP_004374                                                              15    9605
NP_001120662                                                           15    9605
NP_001161328                                                           15    9605
NP_060653                                                              15    9605
NP_001253989                                                           15    9605
NP_001253990                                                           15    9605
NP_001253988                                                           15    9605
NP_055563                                                              15    9605
NP_005301                                                              15    9605
NP_001269340                                                           15    9605
NP_002703                                                              15    9605
NP_001269338                                                           15    9605
NP_001269343                                                           15    9605
NP_001269339                                                           15    9605
NP_001269342                                                           15    9605
NP_001275990                                                           15    9605
NP_001275987                                                           15    9605
NP_647611                                                              15    9605
NP_647612                                                              15    9605
NP_001269341                                                           15    9605
NP_112168                                                              15    9605
NP_002369                                                              15    9605
NP_001229371                                                           15    9605
NP_001025173                                                           15    9605
NP_001229372                                                           15    9605
XP_006724172                                                           15    9605
XP_006724171                                                           15    9605
XP_006724170                                                           15    9605
XP_005254222                                                           15    9605
XP_005253633                                                           15    9605
XP_005253632                                                           15    9605
XP_006719537                                                           15    9605
XP_006719536                                                           15    9605
XP_005253630                                                           15    9605
XP_005253629                                                           15    9605
XP_006718343                                                           15    9605
XP_006718342                                                           15    9605
XP_006718341                                                           15    9605
NP_689449                                                              15    9605
>NP_066958
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR+V
Sbjct: 72 KVFLVRKV 79
>NP_001006933
          Length = 741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR+V
Sbjct: 80 KVFLVRKV 87
>NP_002944
          Length = 735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR+V
Sbjct: 75 KVFLVRKV 82
>NP_001006666
          Length = 744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR+V
Sbjct: 84 KVFLVRKV 91
>XP_005267149
          Length = 758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLFLVREV 9
           K+FLVR+V
Sbjct: 97  KVFLVRKV 104
>XP_006715612
          Length = 761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLFLVREV 9
           K+FLVR+V
Sbjct: 100 KVFLVRKV 107
>XP_005246023
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR+V
Sbjct: 59 KVFLVRKV 66
>NP_872198
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR++
Sbjct: 62 KVFLVRKI 69
>NP_055520
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KLFLVREV 9
           KLF VREV
Sbjct: 776 KLFDVREV 783
>NP_008937
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KKLFLVR 7
           KKLFLV+
Sbjct: 172 KKLFLVQ 178
>NP_004746
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KLFLVREV 9
          K+FLVR++
Sbjct: 62 KVFLVRKI 69
>NP_064710
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFLVREV 9
           LFLVRE+
Sbjct: 884 LFLVREL 890
>XP_005272668
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KLFLVRE 8
          KLFL+R+
Sbjct: 78 KLFLIRD 84
>XP_005272667
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KLFLVRE 8
          KLFL+R+
Sbjct: 78 KLFLIRD 84
>XP_006724596
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KLFLVRE 8
          KLFL+R+
Sbjct: 78 KLFLIRD 84
>XP_005255493
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFLVREV 9
           LFLVRE+
Sbjct: 791 LFLVREL 797
>XP_006721128
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFLVREV 9
           LFLVRE+
Sbjct: 817 LFLVREL 823
>XP_005255492
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFLVREV 9
           LFLVRE+
Sbjct: 858 LFLVREL 864
>XP_005251100
          Length = 2103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KKLFLVREV 9
            +K+F VREV
Sbjct: 2086 EKVFKVREV 2094
>XP_006716252
          Length = 1937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KLFLVREV 9
           KLF VREV
Sbjct: 776 KLFDVREV 783
>XP_006716251
          Length = 1975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KLFLVREV 9
           KLF VREV
Sbjct: 776 KLFDVREV 783
>NP_004374
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 103 LFLVRE 108
>NP_001120662
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 103 LFLVRE 108
>NP_001161328
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1228 KKLFLV 1233
>NP_060653
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1227 KKLFLV 1232
>NP_001253989
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 137 LFLVRE 142
>NP_001253990
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 142 LFLVRE 147
>NP_001253988
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 150 LFLVRE 155
>NP_055563
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 162 LFLVRE 167
>NP_005301
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 454 LFLVRE 459
>NP_001269340
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 124 KKLFLV 129
>NP_002703
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 167 KKLFLV 172
>NP_001269338
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 124 KKLFLV 129
>NP_001269343
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 108 KKLFLV 113
>NP_001269339
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 167 KKLFLV 172
>NP_001269342
          Length = 301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 108 KKLFLV 113
>NP_001275990
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 186 KKMYLVMEL 194
>NP_001275987
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 145 KKMYLVMEL 153
>NP_647611
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 102 LFLVRE 107
>NP_647612
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 143 LFLVRE 148
>NP_001269341
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKLFLV 6
           KKLFLV
Sbjct: 151 KKLFLV 156
>NP_112168
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 186 KKMYLVMEL 194
>NP_002369
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 144 LFLVRE 149
>NP_001229371
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 477 LFLVRE 482
>NP_001025173
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 454 LFLVRE 459
>NP_001229372
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 454 LFLVRE 459
>XP_006724172
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KKLFLVREV 9
          KKL LVR V
Sbjct: 84 KKLQLVRRV 92
>XP_006724171
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KKLFLVREV 9
          KKL LVR V
Sbjct: 84 KKLQLVRRV 92
>XP_006724170
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KKLFLVREV 9
          KKL LVR V
Sbjct: 84 KKLQLVRRV 92
>XP_005254222
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFLVRE 8
           LFLVRE
Sbjct: 103 LFLVRE 108
>XP_005253633
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1227 KKLFLV 1232
>XP_005253632
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1227 KKLFLV 1232
>XP_006719537
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1228 KKLFLV 1233
>XP_006719536
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1228 KKLFLV 1233
>XP_005253630
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1228 KKLFLV 1233
>XP_005253629
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KKLFLV 6
            KKLFLV
Sbjct: 1228 KKLFLV 1233
>XP_006718343
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 145 KKMYLVMEL 153
>XP_006718342
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 186 KKMYLVMEL 194
>XP_006718341
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKLFLVREV 9
           KK++LV E+
Sbjct: 145 KKMYLVMEL 153
>NP_689449
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  KKLFLVREV 9
          KKL LVR V
Sbjct: 84 KKLQLVRRV 92
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.153    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 437,864
Number of extensions: 772
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package