Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000305                                                              20     390
XP_006717989                                                           20     390
NP_000195                                                              18    1482
XP_006714273                                                           18    1482
XP_005263033                                                           18    1482
XP_006714272                                                           18    1482
XP_005263032                                                           18    1482
NP_005372                                                              17    2528
NP_006182                                                              17    4312
NP_005915                                                              16    5631
NP_115996                                                              16    5631
NP_001258926                                                           16    5631
NP_001258925                                                           16    5631
NP_001258924                                                           16    5631
NP_002244                                                              16    5631
NP_001123633                                                           16    5631
XP_006719480                                                           16    5631
XP_006719479                                                           16    5631
XP_006719478                                                           16    5631
XP_006719477                                                           16    5631
XP_006719476                                                           16    5631
XP_006719475                                                           16    5631
XP_006717757                                                           16    5631
XP_006717756                                                           16    5631
NP_001123631                                                           16    5631
NP_689922                                                              16    5631
NP_848645                                                              16    7355
NP_002906                                                              16    7355
XP_005245183                                                           16    7355
XP_006711352                                                           16    7355
XP_005245182                                                           16    7355
NP_853536                                                              16    7355
NP_004360                                                              15    9605
NP_003048                                                              15    9605
NP_055105                                                              15    9605
NP_001005783                                                           15    9605
NP_037407                                                              15    9605
NP_056234                                                              15    9605
NP_001243112                                                           15    9605
NP_001243111                                                           15    9605
NP_001269789                                                           15    9605
NP_001269787                                                           15    9605
NP_001269790                                                           15    9605
NP_115668                                                              15    9605
NP_057611                                                              15    9605
NP_001269785                                                           15    9605
NP_001116118                                                           15    9605
XP_005274542                                                           15    9605
XP_006721247                                                           15    9605
XP_006721246                                                           15    9605
XP_006721245                                                           15    9605
XP_006721244                                                           15    9605
XP_006712629                                                           15    9605
XP_006712628                                                           15    9605
XP_006712627                                                           15    9605
XP_005246122                                                           15    9605
XP_006712316                                                           15    9605
XP_005245341                                                           15    9605
XP_006711459                                                           15    9605
XP_005245340                                                           15    9605
XP_006711458                                                           15    9605
XP_006711457                                                           15    9605
XP_006711456                                                           15    9605
XP_006711133                                                           15    9605
XP_005270972                                                           15    9605
XP_005270971                                                           15    9605
XP_005270970                                                           15    9605
NP_848600                                                              15    9605
>NP_000305
          Length = 403

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           KKGV IPSQ
Sbjct: 163 KKGVTIPSQ 171
>XP_006717989
          Length = 388

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           KKGV IPSQ
Sbjct: 148 KKGVTIPSQ 156
>NP_000195
          Length = 583

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           K GV IPSQ
Sbjct: 267 KSGVCIPSQ 275
>XP_006714273
          Length = 531

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           K GV IPSQ
Sbjct: 267 KSGVCIPSQ 275
>XP_005263033
          Length = 576

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           K GV IPSQ
Sbjct: 267 KSGVCIPSQ 275
>XP_006714272
          Length = 590

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           K GV IPSQ
Sbjct: 267 KSGVCIPSQ 275
>XP_005263032
          Length = 591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           K GV IPSQ
Sbjct: 267 KSGVCIPSQ 275
>NP_005372
          Length = 710

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           KKG AIP++
Sbjct: 124 KKGAAIPAK 132
>NP_006182
          Length = 394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KKGVAIPS 8
          KKG+A P+
Sbjct: 71 KKGIAFPT 78
>NP_005915
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           KKG  +PS+
Sbjct: 263 KKGTLLPSE 271
>NP_115996
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +P+Q
Sbjct: 225 KEGITLPTQ 233
>NP_001258926
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +P+Q
Sbjct: 225 KEGITLPTQ 233
>NP_001258925
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +P+Q
Sbjct: 223 KEGITLPTQ 231
>NP_001258924
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +P+Q
Sbjct: 224 KEGITLPTQ 232
>NP_002244
          Length = 1356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KKGVAIPS 8
           KKG  IPS
Sbjct: 182 KKGFTIPS 189
>NP_001123633
          Length = 989

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVAIPSQ 9
           G+AIPS+
Sbjct: 155 GIAIPSE 161
>XP_006719480
          Length = 2035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1343 KRGPAIPS 1350
>XP_006719479
          Length = 2059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1367 KRGPAIPS 1374
>XP_006719478
          Length = 2078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1390 KRGPAIPS 1397
>XP_006719477
          Length = 2082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1390 KRGPAIPS 1397
>XP_006719476
          Length = 2082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1390 KRGPAIPS 1397
>XP_006719475
          Length = 2082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KKGVAIPS 8
            K+G AIPS
Sbjct: 1390 KRGPAIPS 1397
>XP_006717757
          Length = 879

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GVAIPSQ 9
          G+AIPS+
Sbjct: 45 GIAIPSE 51
>XP_006717756
          Length = 879

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GVAIPSQ 9
          G+AIPS+
Sbjct: 45 GIAIPSE 51
>NP_001123631
          Length = 227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVAIPSQ 9
           G+AIPS+
Sbjct: 155 GIAIPSE 161
>NP_689922
          Length = 989

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVAIPSQ 9
           G+AIPS+
Sbjct: 155 GIAIPSE 161
>NP_848645
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KGVAIPSQ 9
           KG+++P Q
Sbjct: 173 KGISVPCQ 180
>NP_002906
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +PSQ
Sbjct: 202 KEGLNLPSQ 210
>XP_005245183
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KGVAIPSQ 9
           KG+++P Q
Sbjct: 172 KGISVPCQ 179
>XP_006711352
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KGVAIPSQ 9
           KG+++P Q
Sbjct: 172 KGISVPCQ 179
>XP_005245182
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KGVAIPSQ 9
           KG+++P Q
Sbjct: 184 KGISVPCQ 191
>NP_853536
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+ +PSQ
Sbjct: 202 KEGLNLPSQ 210
>NP_004360
          Length = 3177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           K G+A+PS
Sbjct: 155 KDGLALPS 162
>NP_003048
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KGVAIP 7
           KGVA+P
Sbjct: 517 KGVALP 522
>NP_055105
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  KKGVAIP 7
          K GVA+P
Sbjct: 19 KNGVALP 25
>NP_001005783
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KKGVAIP 7
           KKG AIP
Sbjct: 186 KKGNAIP 192
>NP_037407
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1632 KKGLDIPAK 1640
>NP_056234
          Length = 2828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           KKG  +PS+
Sbjct: 670 KKGSGLPSK 678
>NP_001243112
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1632 KKGLDIPAK 1640
>NP_001243111
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1632 KKGLDIPAK 1640
>NP_001269789
          Length = 2241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>NP_001269787
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>NP_001269790
          Length = 1529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>NP_115668
          Length = 1529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>NP_057611
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KKGVAIP 7
           KKG AIP
Sbjct: 186 KKGNAIP 192
>NP_001269785
          Length = 2241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>NP_001116118
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+A+P +
Sbjct: 164 KRGLALPEK 172
>XP_005274542
          Length = 2853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           KKG  +PS+
Sbjct: 695 KKGSGLPSK 703
>XP_006721247
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1533 KKGLDIPAK 1541
>XP_006721246
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1589 KKGLDIPAK 1597
>XP_006721245
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1598 KKGLDIPAK 1606
>XP_006721244
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KKGVAIPSQ 9
            KKG+ IP++
Sbjct: 1598 KKGLDIPAK 1606
>XP_006712629
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+A+P +
Sbjct: 164 KRGLALPEK 172
>XP_006712628
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+A+P +
Sbjct: 164 KRGLALPEK 172
>XP_006712627
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KKGVAIPSQ 9
           K+G+A+P +
Sbjct: 164 KRGLALPEK 172
>XP_005246122
          Length = 2977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           K G+A+PS
Sbjct: 155 KDGLALPS 162
>XP_006712316
          Length = 3010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           K G+A+PS
Sbjct: 155 KDGLALPS 162
>XP_005245341
          Length = 2068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 163 EKGVVIPT 170
>XP_006711459
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>XP_005245340
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>XP_006711458
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>XP_006711457
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>XP_006711456
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KKGVAIPS 8
           +KGV IP+
Sbjct: 335 EKGVVIPT 342
>XP_006711133
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KKGVAIPSQ 9
           ++GV +P Q
Sbjct: 383 RRGVPVPEQ 391
>XP_005270972
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KKGVAIP 7
           KKG AIP
Sbjct: 199 KKGNAIP 205
>XP_005270971
          Length = 395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KKGVAIP 7
           KKG AIP
Sbjct: 174 KKGNAIP 180
>XP_005270970
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KKGVAIP 7
           KKG AIP
Sbjct: 199 KKGNAIP 205
>NP_848600
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KKGVAIP 7
           K+G+AIP
Sbjct: 347 KEGLAIP 353
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.125    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 713,742
Number of extensions: 1621
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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