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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              20     390
NP_001243397                                                           20     390
XP_005269721                                                           20     390
NP_001073936                                                           17    3301
NP_036260                                                              17    3301
XP_006710516                                                           17    3301
NP_689845                                                              16    5631
NP_056054                                                              16    7355
NP_001273646                                                           16    7355
NP_056078                                                              16    7355
NP_003483                                                              16    7355
NP_001167587                                                           16    7355
NP_001167588                                                           16    7355
NP_001273644                                                           16    7355
NP_001269308                                                           16    7355
NP_079334                                                              16    7355
NP_001243529                                                           16    7355
NP_001269307                                                           16    7355
NP_001243528                                                           16    7355
NP_001243530                                                           16    7355
XP_005254315                                                           16    7355
XP_005254314                                                           16    7355
XP_006720509                                                           16    7355
XP_005254313                                                           16    7355
XP_005254312                                                           16    7355
XP_005251906                                                           16    7355
XP_005251905                                                           16    7355
XP_005251904                                                           16    7355
XP_006716564                                                           16    7355
XP_005250826                                                           16    7355
NP_001106                                                              16    7355
NP_001934                                                              15    9605
NP_078966                                                              15    9605
NP_997257                                                              15    9605

>NP_036462
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KITTSSTYI 9
           KITT+STYI
Sbjct: 412 KITTTSTYI 420



>NP_001243397
          Length = 1890

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KITTSSTYI 9
           KITT+STYI
Sbjct: 412 KITTTSTYI 420



>XP_005269721
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KITTSSTYI 9
           KITT+STYI
Sbjct: 412 KITTTSTYI 420



>NP_001073936
          Length = 1848

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITTSSTYI 9
           +TTS TY+
Sbjct: 382 VTTSETYV 389



>NP_036260
          Length = 919

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  ITTSSTYI 9
          +TT+STY+
Sbjct: 56 VTTASTYL 63



>XP_006710516
          Length = 514

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  ITTSSTYI 9
          +TT+STY+
Sbjct: 56 VTTASTYL 63



>NP_689845
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ITTSSTYI 9
           + TSSTYI
Sbjct: 803 LPTSSTYI 810



>NP_056054
          Length = 1186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1125 KVTSPTTYV 1133



>NP_001273646
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1177 KVTSPTTYV 1185



>NP_056078
          Length = 3036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>NP_003483
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TTSSTYI 9
           TTS+TY+
Sbjct: 188 TTSATYL 194



>NP_001167587
          Length = 3037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>NP_001167588
          Length = 2400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1128 TSSTYI 1133



>NP_001273644
          Length = 1278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1217 KVTSPTTYV 1225



>NP_001269308
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 273 KLTKSLTYI 281



>NP_079334
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 273 KLTKSLTYI 281



>NP_001243529
          Length = 717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 260 KLTKSLTYI 268



>NP_001269307
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 147 KLTKSLTYI 155



>NP_001243528
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 250 KLTKSLTYI 258



>NP_001243530
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K+T S TYI
Sbjct: 260 KLTKSLTYI 268



>XP_005254315
          Length = 2576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>XP_005254314
          Length = 2605

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>XP_006720509
          Length = 2646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>XP_005254313
          Length = 3057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>XP_005254312
          Length = 3058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TSSTYI 9
            TSSTYI
Sbjct: 1764 TSSTYI 1769



>XP_005251906
          Length = 1108

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1047 KVTSPTTYV 1055



>XP_005251905
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1165 KVTSPTTYV 1173



>XP_005251904
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    KITTSSTYI 9
            K+T+ +TY+
Sbjct: 1165 KVTSPTTYV 1173



>XP_006716564
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K TTS TY+
Sbjct: 234 KDTTSHTYL 242



>XP_005250826
          Length = 1221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K TTS TY+
Sbjct: 234 KDTTSHTYL 242



>NP_001106
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KITTSSTYI 9
           K TTS TY+
Sbjct: 234 KDTTSHTYL 242



>NP_001934
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ITTSSTYI 9
            ITTSST +
Sbjct: 1100 ITTSSTRV 1107



>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KITTSSTY 8
            K+T SST+
Sbjct: 1164 KVTMSSTF 1171



>NP_997257
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ITTSSTYI 9
           ITTS T+I
Sbjct: 205 ITTSYTFI 212



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.114    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 310,285
Number of extensions: 337
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)