Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
NP_001072                                                              17    2528
NP_055859                                                              17    4312
NP_001668                                                              17    4312
NP_055042                                                              15    9605
NP_612385                                                              15    9605
XP_006724371                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2593 KIQALLLTV 2601
>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2614 KIQALLLTV 2622
>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2624 KIQALLLTV 2632
>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2624 KIQALLLTV 2632
>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2593 KIQALLLTV 2601
>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2603 KIQALLLTV 2611
>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2624 KIQALLLTV 2632
>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2611 KIQALLLTV 2619
>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2614 KIQALLLTV 2622
>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIQVLLLTV 9
            KIQ LLLTV
Sbjct: 2624 KIQALLLTV 2632
>NP_001072
          Length = 3623

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KIQVLLLT 8
            K+QVLLLT
Sbjct: 1365 KLQVLLLT 1372
>NP_055859
          Length = 613

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KIQVLLLTV 9
           ++QVLLLT+
Sbjct: 513 EVQVLLLTM 521
>NP_001668
          Length = 303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  IQVLLLTV 9
          IQV+LLT+
Sbjct: 54 IQVMLLTI 61
>NP_055042
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KIQVLLLTV 9
           +I VLLLTV
Sbjct: 427 RIFVLLLTV 435
>NP_612385
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KIQVLLLT 8
          K QVL+LT
Sbjct: 67 KAQVLMLT 74
>XP_006724371
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KIQVLLLTV 9
           +I VLLLTV
Sbjct: 381 RIFVLLLTV 389
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.151    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 314,065
Number of extensions: 246
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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