Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              18    1935
NP_570712                                                              18    1935
NP_570714                                                              18    1935
NP_570713                                                              18    1935
NP_570716                                                              18    1935
NP_000235                                                              18    1935
NP_570715                                                              18    1935
XP_006718620                                                           18    1935
XP_005274059                                                           18    1935
XP_005274060                                                           18    1935
XP_005274058                                                           18    1935
NP_524144                                                              17    2528
NP_001135745                                                           16    5631
NP_001135746                                                           16    5631
NP_001193980                                                           16    5631
NP_056097                                                              16    5631
NP_055912                                                              16    5631
NP_001193973                                                           16    5631
NP_001273606                                                           16    5631
NP_073616                                                              16    5631
NP_689661                                                              16    5631
XP_005272265                                                           16    5631
XP_005272264                                                           16    5631
XP_006713123                                                           16    5631
XP_006713121                                                           16    5631
XP_006713120                                                           16    5631
XP_006713119                                                           16    5631
XP_006713118                                                           16    5631
XP_006713117                                                           16    5631
XP_006713116                                                           16    5631
XP_006713115                                                           16    5631
XP_006713114                                                           16    5631
XP_006713113                                                           16    5631
XP_006713112                                                           16    5631
XP_006713111                                                           16    5631
XP_006713110                                                           16    5631
XP_006713109                                                           16    5631
XP_006713108                                                           16    5631
XP_006713107                                                           16    5631
XP_006713106                                                           16    5631
XP_006713105                                                           16    5631
XP_006713104                                                           16    5631
XP_006713103                                                           16    5631
XP_006713102                                                           16    5631
XP_006713101                                                           16    5631
XP_006713100                                                           16    5631
XP_006713099                                                           16    5631
XP_006712448                                                           16    5631
XP_006712447                                                           16    5631
XP_006712446                                                           16    5631
XP_006712445                                                           16    5631
XP_006712444                                                           16    5631
XP_006712443                                                           16    5631
XP_006712442                                                           16    5631
XP_006712441                                                           16    5631
XP_006712440                                                           16    5631
XP_006712439                                                           16    5631
XP_006712438                                                           16    5631
XP_006712437                                                           16    5631
XP_006712436                                                           16    5631
NP_620150                                                              16    7355
NP_060654                                                              16    7355
NP_066919                                                              15    9605
NP_001003406                                                           15    9605
>NP_570711
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 569 KINSSAIKL 577
>NP_570712
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>NP_570714
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>NP_570713
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>NP_570716
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>NP_000235
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>NP_570715
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 574 KINSSAIKL 582
>XP_006718620
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 569 KINSSAIKL 577
>XP_005274059
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 569 KINSSAIKL 577
>XP_005274060
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 569 KINSSAIKL 577
>XP_005274058
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN SAIKL
Sbjct: 569 KINSSAIKL 577
>NP_524144
          Length = 194

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  KINLSAIKL 9
          KI+LSAIK+
Sbjct: 37 KIDLSAIKI 45
>NP_001135745
          Length = 1479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1379 INLAAIKM 1386
>NP_001135746
          Length = 1471

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1371 INLAAIKM 1378
>NP_001193980
          Length = 1477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1377 INLAAIKM 1384
>NP_056097
          Length = 1538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1438 INLAAIKM 1445
>NP_055912
          Length = 1515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1415 INLAAIKM 1422
>NP_001193973
          Length = 1294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1194 INLAAIKM 1201
>NP_001273606
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           + NLSA+KL
Sbjct: 270 EFNLSALKL 278
>NP_073616
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN+S IK+
Sbjct: 647 KINVSEIKM 655
>NP_689661
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KINLSAIK 8
           +IN+SAIK
Sbjct: 207 EINMSAIK 214
>XP_005272265
          Length = 722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN+S IK+
Sbjct: 518 KINVSEIKM 526
>XP_005272264
          Length = 755

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KINLSAIKL 9
           KIN+S IK+
Sbjct: 551 KINVSEIKM 559
>XP_006713123
          Length = 1514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1414 INLAAIKM 1421
>XP_006713121
          Length = 1286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1186 INLAAIKM 1193
>XP_006713120
          Length = 1287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1187 INLAAIKM 1194
>XP_006713119
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1208 INLAAIKM 1215
>XP_006713118
          Length = 1328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1228 INLAAIKM 1235
>XP_006713117
          Length = 1334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1234 INLAAIKM 1241
>XP_006713116
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1407 INLAAIKM 1414
>XP_006713115
          Length = 1514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1414 INLAAIKM 1421
>XP_006713114
          Length = 1523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1423 INLAAIKM 1430
>XP_006713113
          Length = 1524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1424 INLAAIKM 1431
>XP_006713112
          Length = 1527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1427 INLAAIKM 1434
>XP_006713111
          Length = 1532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1432 INLAAIKM 1439
>XP_006713110
          Length = 1533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1433 INLAAIKM 1440
>XP_006713109
          Length = 1537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1437 INLAAIKM 1444
>XP_006713108
          Length = 1541

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1441 INLAAIKM 1448
>XP_006713107
          Length = 1544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1444 INLAAIKM 1451
>XP_006713106
          Length = 1545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1445 INLAAIKM 1452
>XP_006713105
          Length = 1545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1445 INLAAIKM 1452
>XP_006713104
          Length = 1552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1452 INLAAIKM 1459
>XP_006713103
          Length = 1553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1453 INLAAIKM 1460
>XP_006713102
          Length = 1554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1454 INLAAIKM 1461
>XP_006713101
          Length = 1561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1461 INLAAIKM 1468
>XP_006713100
          Length = 1561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1461 INLAAIKM 1468
>XP_006713099
          Length = 1562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1462 INLAAIKM 1469
>XP_006712448
          Length = 1255

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1155 INLAAIKM 1162
>XP_006712447
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1164 INLAAIKM 1171
>XP_006712446
          Length = 1454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1354 INLAAIKM 1361
>XP_006712445
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1362 INLAAIKM 1369
>XP_006712444
          Length = 1470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1370 INLAAIKM 1377
>XP_006712443
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1378 INLAAIKM 1385
>XP_006712442
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1378 INLAAIKM 1385
>XP_006712441
          Length = 1486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1386 INLAAIKM 1393
>XP_006712440
          Length = 1487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1387 INLAAIKM 1394
>XP_006712439
          Length = 1487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1387 INLAAIKM 1394
>XP_006712438
          Length = 1494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1394 INLAAIKM 1401
>XP_006712437
          Length = 1494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1394 INLAAIKM 1401
>XP_006712436
          Length = 1495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    INLSAIKL 9
            INL+AIK+
Sbjct: 1395 INLAAIKM 1402
>NP_620150
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KINLSAIK 8
           K+NLSAI+
Sbjct: 146 KMNLSAIQ 153
>NP_060654
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KINLSAIK 8
           K+NLSAI+
Sbjct: 146 KMNLSAIQ 153
>NP_066919
          Length = 2223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   INLSAIK 8
           INLSAI+
Sbjct: 172 INLSAIR 178
>NP_001003406
          Length = 2188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   INLSAIK 8
           INLSAI+
Sbjct: 172 INLSAIR 178
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.135    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 291,638
Number of extensions: 384
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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