Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              19     665
NP_001008723                                                           18    1935
NP_055592                                                              17    3301
NP_001128128                                                           17    3301
NP_997287                                                              17    3301
XP_005273417                                                           17    3301
NP_001024                                                              16    5631
NP_079535                                                              16    5631
NP_751897                                                              16    5631
NP_006092                                                              16    5631
NP_001269633                                                           16    5631
NP_001269634                                                           16    5631
NP_001269635                                                           16    5631
NP_055612                                                              16    5631
NP_005733                                                              16    5631
NP_001157785                                                           16    5631
NP_001269636                                                           16    5631
XP_006726466                                                           16    5631
XP_006712969                                                           16    5631
XP_005246202                                                           16    5631
XP_006711919                                                           16    5631
XP_006710208                                                           16    5631
NP_004735                                                              16    7355
NP_001258579                                                           16    7355
NP_071906                                                              16    7355
NP_001127905                                                           16    7355
NP_851607                                                              16    7355
NP_001127904                                                           16    7355
NP_065156                                                              16    7355
XP_005274116                                                           16    7355
XP_006718652                                                           16    7355
XP_005274115                                                           16    7355
XP_005274114                                                           16    7355
XP_006714475                                                           16    7355
XP_005265449                                                           16    7355
XP_006711530                                                           16    7355
XP_006711529                                                           16    7355
XP_006711528                                                           16    7355
NP_036547                                                              15    9605
NP_001192192                                                           15    9605
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_001138508                                                           15    9605
NP_031383                                                              15    9605
NP_002526                                                              15    9605
NP_058197                                                              15    9605
NP_037375                                                              15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
>NP_002430
          Length = 1137

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           KILNEQ AK
Sbjct: 687 KILNEQAAK 695
>NP_001008723
          Length = 872

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           KILNE+ AK
Sbjct: 264 KILNERAAK 272
>NP_055592
          Length = 1524

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KILNEQVAK 9
           KI+NE+VA+
Sbjct: 101 KIINERVAE 109
>NP_001128128
          Length = 452

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           KILNEQ+
Sbjct: 210 KILNEQI 216
>NP_997287
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           KILNEQ+
Sbjct: 184 KILNEQI 190
>XP_005273417
          Length = 1487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   KILNEQVAK 9
           KI+NE+VA+
Sbjct: 101 KIINERVAE 109
>NP_001024
          Length = 792

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           K+L E++AK
Sbjct: 582 KVLKEKIAK 590
>NP_079535
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LNEQVAK 9
           LN+QVAK
Sbjct: 669 LNQQVAK 675
>NP_751897
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LNEQVAK 9
           LN+QVAK
Sbjct: 652 LNQQVAK 658
>NP_006092
          Length = 642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           + LNEQ+A+
Sbjct: 273 RALNEQIAR 281
>NP_001269633
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 332 EIINEDIAK 340
>NP_001269634
          Length = 488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 328 EIINEDIAK 336
>NP_001269635
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 285 EIINEDIAK 293
>NP_055612
          Length = 697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           +LNEQ+A
Sbjct: 206 VLNEQIA 212
>NP_005733
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 280 EIINEDIAK 288
>NP_001157785
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           +LNEQ+A
Sbjct: 206 VLNEQIA 212
>NP_001269636
          Length = 437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 277 EIINEDIAK 285
>XP_006726466
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KILNEQVA 8
            K+L EQVA
Sbjct: 1277 KVLEEQVA 1284
>XP_006712969
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KILNEQVA 8
            K+L EQVA
Sbjct: 1277 KVLEEQVA 1284
>XP_005246202
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 280 EIINEDIAK 288
>XP_006711919
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KILNEQVAK 9
           +I+NE +AK
Sbjct: 280 EIINEDIAK 288
>XP_006710208
          Length = 666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KILNEQVA 8
           K+L EQVA
Sbjct: 633 KVLEEQVA 640
>NP_004735
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILNEQVAK 9
           +LNE+VA+
Sbjct: 136 LLNEEVAR 143
>NP_001258579
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KILNEQV 7
          K+LNEQ+
Sbjct: 10 KVLNEQL 16
>NP_071906
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           K+LNEQ+
Sbjct: 122 KVLNEQL 128
>NP_001127905
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           K+LNEQ+
Sbjct: 122 KVLNEQL 128
>NP_851607
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           ILNEQV+
Sbjct: 204 ILNEQVS 210
>NP_001127904
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           K+LNEQ+
Sbjct: 122 KVLNEQL 128
>NP_065156
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           ILNEQV+
Sbjct: 204 ILNEQVS 210
>XP_005274116
          Length = 1602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILNEQVAK 9
           KI+NE V K
Sbjct: 592 KIINEHVDK 600
>XP_006718652
          Length = 2196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KILNEQVAK 9
            KI+NE V K
Sbjct: 1162 KIINEHVDK 1170
>XP_005274115
          Length = 2222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KILNEQVAK 9
            KI+NE V K
Sbjct: 1188 KIINEHVDK 1196
>XP_005274114
          Length = 2223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KILNEQVAK 9
            KI+NE V K
Sbjct: 1189 KIINEHVDK 1197
>XP_006714475
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILNEQVAK 9
           +LNE+VA+
Sbjct: 136 LLNEEVAR 143
>XP_005265449
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILNEQV 7
           K+LNEQ+
Sbjct: 122 KVLNEQL 128
>XP_006711530
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           ILNEQV+
Sbjct: 204 ILNEQVS 210
>XP_006711529
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILNEQVA 8
          ILNEQV+
Sbjct: 62 ILNEQVS 68
>XP_006711528
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILNEQVA 8
           ILNEQV+
Sbjct: 204 ILNEQVS 210
>NP_036547
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KILNEQVAK 9
           K+LN QV +
Sbjct: 561 KLLNSQVVR 569
>NP_001192192
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KILNEQVAK 9
           K+LN QV +
Sbjct: 377 KLLNSQVVR 385
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3433 KLLNEEV 3439
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>NP_001138508
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILNEQVAK 9
           KILN Q +K
Sbjct: 145 KILNSQSSK 153
>NP_031383
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILNEQVAK 9
           KILN Q +K
Sbjct: 145 KILNSQSSK 153
>NP_002526
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KILNEQVA 8
           K+LNE V+
Sbjct: 472 KVLNESVS 479
>NP_058197
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KILNEQVA 8
           K+LNE V+
Sbjct: 472 KVLNESVS 479
>NP_037375
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LNEQVAK 9
          LNEQ+A+
Sbjct: 42 LNEQIAE 48
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3387 KLLNEEV 3393
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3388 KLLNEEV 3394
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3433 KLLNEEV 3439
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3393 KLLNEEV 3399
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3416 KLLNEEV 3422
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3423 KLLNEEV 3429
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3433 KLLNEEV 3439
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KILNEQV 7
            K+LNE+V
Sbjct: 3440 KLLNEEV 3446
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.124    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 377,668
Number of extensions: 511
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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