Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              20     390
NP_001087241                                                           20     390
XP_006714101                                                           20     390
XP_005265799                                                           20     390
XP_005265798                                                           20     390
XP_005265797                                                           20     390
NP_689500                                                              17    3301
NP_001106997                                                           17    3301
NP_001034589                                                           17    3301
XP_005256385                                                           17    3301
XP_006721400                                                           17    3301
XP_005256381                                                           17    3301
XP_006710423                                                           17    3301
NP_116248                                                              16    5631
NP_001240813                                                           16    5631
NP_055437                                                              16    5631
NP_938057                                                              16    5631
NP_079420                                                              16    5631
NP_001095876                                                           16    5631
XP_005263305                                                           16    5631
XP_005263304                                                           16    5631
XP_006714389                                                           16    5631
XP_005263303                                                           16    5631
XP_005263302                                                           16    5631
NP_001123614                                                           16    5631
NP_002009                                                              16    7355
NP_001128526                                                           16    7355
NP_001128525                                                           16    7355
NP_068577                                                              16    7355
NP_003254                                                              16    7355
NP_001243193                                                           16    7355
NP_001243194                                                           16    7355
XP_005256615                                                           16    7355
XP_005256613                                                           16    7355
XP_005256612                                                           16    7355
XP_006721109                                                           16    7355
XP_005255374                                                           16    7355
XP_005255373                                                           16    7355
XP_005253105                                                           16    7355
XP_005253104                                                           16    7355
XP_005253102                                                           16    7355
XP_005253103                                                           16    7355
XP_005253101                                                           16    7355
XP_005262723                                                           16    7355
XP_005262722                                                           16    7355
XP_006714091                                                           16    7355
XP_005262720                                                           16    7355
XP_005262719                                                           16    7355
NP_001013009                                                           16    7355
NP_065783                                                              15    9605
NP_059989                                                              15    9605
NP_003092                                                              15    9605
NP_001239441                                                           15    9605
NP_055086                                                              15    9605
NP_001010870                                                           15    9605
NP_001239440                                                           15    9605
NP_001161831                                                           15    9605
NP_001059                                                              15    9605
NP_060104                                                              15    9605
XP_005274498                                                           15    9605
XP_005273602                                                           15    9605
XP_005273601                                                           15    9605
XP_005273600                                                           15    9605
XP_005273599                                                           15    9605
XP_005273598                                                           15    9605
XP_006715590                                                           15    9605
XP_005267126                                                           15    9605
XP_006715589                                                           15    9605
XP_006715588                                                           15    9605
XP_006715587                                                           15    9605
XP_006715586                                                           15    9605
XP_005265484                                                           15    9605
>NP_000213
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>NP_001087241
          Length = 972

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>XP_006714101
          Length = 526

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>XP_005265799
          Length = 973

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>XP_005265798
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>XP_005265797
          Length = 977

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KIFLVDRSL 9
           K+FLVDRSL
Sbjct: 116 KLFLVDRSL 124
>NP_689500
          Length = 539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIFLVDRSL 9
           K+F++DR L
Sbjct: 399 KVFMIDRYL 407
>NP_001106997
          Length = 614

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIFLVDRSL 9
           K+F++DR L
Sbjct: 474 KVFMIDRYL 482
>NP_001034589
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IFLVDRS 8
           IFL+DRS
Sbjct: 363 IFLIDRS 369
>XP_005256385
          Length = 400

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIFLVDRSL 9
           K+F++DR L
Sbjct: 260 KVFMIDRYL 268
>XP_006721400
          Length = 539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIFLVDRSL 9
           K+F++DR L
Sbjct: 399 KVFMIDRYL 407
>XP_005256381
          Length = 597

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIFLVDRSL 9
           K+F++DR L
Sbjct: 457 KVFMIDRYL 465
>XP_006710423
          Length = 932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  IFLVDRS 8
          IFL+DRS
Sbjct: 80 IFLIDRS 86
>NP_116248
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           KIFL  RSL
Sbjct: 186 KIFLFGRSL 194
>NP_001240813
          Length = 1166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IFLVDRSL 9
          +FLVDR L
Sbjct: 33 VFLVDRFL 40
>NP_055437
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IFLVDRS 8
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_938057
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IFLVDRS 8
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_079420
          Length = 1244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FLVDR L
Sbjct: 111 VFLVDRFL 118
>NP_001095876
          Length = 1244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FLVDR L
Sbjct: 111 VFLVDRFL 118
>XP_005263305
          Length = 1167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IFLVDRSL 9
          +FLVDR L
Sbjct: 33 VFLVDRFL 40
>XP_005263304
          Length = 1167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IFLVDRSL 9
          +FLVDR L
Sbjct: 33 VFLVDRFL 40
>XP_006714389
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FLVDR L
Sbjct: 111 VFLVDRFL 118
>XP_005263303
          Length = 1245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FLVDR L
Sbjct: 111 VFLVDRFL 118
>XP_005263302
          Length = 1245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FLVDR L
Sbjct: 111 VFLVDRFL 118
>NP_001123614
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IFLVDRS 8
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_002009
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 647 VFLLDRGL 654
>NP_001128526
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>NP_001128525
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>NP_068577
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>NP_003254
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_001243193
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 636 VFLLDRGL 643
>NP_001243194
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 592 VFLLDRGL 599
>XP_005256615
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 646 VFLLDRGL 653
>XP_005256613
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 646 VFLLDRGL 653
>XP_005256612
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IFLVDRSL 9
           +FL+DR L
Sbjct: 647 VFLLDRGL 654
>XP_006721109
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KIFLVDRS 8
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>XP_005255374
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KIFLVDRS 8
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>XP_005255373
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KIFLVDRS 8
           KIF +DR+
Sbjct: 503 KIFYIDRN 510
>XP_005253105
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 141 KLFLDDRDL 149
>XP_005253104
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>XP_005253102
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>XP_005253103
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>XP_005253101
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+FL DR L
Sbjct: 196 KLFLDDRDL 204
>XP_005262723
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262722
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_006714091
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262720
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262719
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_001013009
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KIFLVDRS 8
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>NP_065783
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1797 LFVVDRS 1803
>NP_059989
          Length = 2236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1784 LFVVDRS 1790
>NP_003092
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           KIF+  RSL
Sbjct: 120 KIFIARRSL 128
>NP_001239441
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KIFLVDRSL 9
          KIF+  RSL
Sbjct: 55 KIFIARRSL 63
>NP_055086
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+F+ DR L
Sbjct: 445 KLFIPDRDL 453
>NP_001010870
          Length = 2096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IFLVDR 7
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_001239440
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KIFLVDRSL 9
          KIF+  RSL
Sbjct: 62 KIFIARRSL 70
>NP_001161831
          Length = 2066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IFLVDR 7
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_001059
          Length = 1621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KIFLVDRS 8
           +IF+VDR+
Sbjct: 928 EIFVVDRN 935
>NP_060104
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FLVDRS 8
           FL+DRS
Sbjct: 136 FLIDRS 141
>XP_005274498
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KIFLVDRSL 9
           K+F+ DR L
Sbjct: 445 KLFIPDRDL 453
>XP_005273602
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273601
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273600
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273599
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273598
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  FLVDRS 8
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_006715590
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1825 LFVVDRS 1831
>XP_005267126
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1864 LFVVDRS 1870
>XP_006715589
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1868 LFVVDRS 1874
>XP_006715588
          Length = 2330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1878 LFVVDRS 1884
>XP_006715587
          Length = 2359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1907 LFVVDRS 1913
>XP_006715586
          Length = 2373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IFLVDRS 8
            +F+VDRS
Sbjct: 1921 LFVVDRS 1927
>XP_005265484
          Length = 1626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KIFLVDRS 8
           +IF+VDR+
Sbjct: 933 EIFVVDRN 940
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.157    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 435,698
Number of extensions: 650
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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