Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              17    2528
NP_066997                                                              17    4312
NP_056141                                                              16    7355
NP_001164108                                                           16    7355
NP_065813                                                              16    7355
NP_056493                                                              16    7355
XP_006719869                                                           16    7355
XP_006719868                                                           16    7355
XP_005266408                                                           16    7355
XP_005266407                                                           16    7355
XP_005266403                                                           16    7355
XP_006719867                                                           16    7355
XP_006719866                                                           16    7355
XP_005266405                                                           16    7355
XP_005266404                                                           16    7355
XP_005269099                                                           16    7355
XP_005277479                                                           16    7355
XP_005277478                                                           16    7355
XP_005277477                                                           16    7355
XP_005277476                                                           16    7355
XP_005277572                                                           16    7355
XP_005277571                                                           16    7355
XP_006711310                                                           16    7355
XP_005277570                                                           16    7355
XP_005277569                                                           16    7355
XP_006711309                                                           16    7355
XP_005277568                                                           16    7355
XP_005277567                                                           16    7355
XP_005277387                                                           16    7355
XP_005277386                                                           16    7355
XP_005277556                                                           16    7355
XP_005277555                                                           16    7355
XP_005277554                                                           16    7355
NP_001258816                                                           16    7355
NP_001258799                                                           16    7355
NP_001258801                                                           16    7355
NP_001017520                                                           15    9605
NP_004079                                                              15    9605
NP_061836                                                              15    9605
NP_001264                                                              15    9605
NP_387505                                                              15    9605
XP_005261051                                                           15    9605
XP_006719025                                                           15    9605
XP_005253725                                                           15    9605
XP_006719024                                                           15    9605
XP_006719023                                                           15    9605
XP_006719022                                                           15    9605
XP_006719021                                                           15    9605
NP_057382                                                              15    9605



>NP_722576
          Length = 3080

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KIESSEVKS 9
           K ESSEVKS
Sbjct: 165 KNESSEVKS 173





>NP_066997
          Length = 923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KIESSEVKS 9
           K+E SEV+S
Sbjct: 667 KLEDSEVRS 675





>NP_056141
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>NP_001164108
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>NP_065813
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 370 KIENEEVK 377





>NP_056493
          Length = 2946

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_006719869
          Length = 2943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_006719868
          Length = 2938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_005266408
          Length = 1934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_005266407
          Length = 2641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KIESSEVK 8
           K+E++EVK
Sbjct: 737 KVEATEVK 744





>XP_005266403
          Length = 2941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_006719867
          Length = 2961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_006719866
          Length = 2962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_005266405
          Length = 2964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_005266404
          Length = 2967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KIESSEVK 8
            K+E++EVK
Sbjct: 1063 KVEATEVK 1070





>XP_005269099
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 370 KIENEEVK 377





>XP_005277479
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277478
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277477
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>XP_005277476
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>XP_005277572
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>XP_005277571
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>XP_006711310
          Length = 849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>XP_005277570
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277569
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_006711309
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>XP_005277568
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>XP_005277567
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>XP_005277387
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 227 KIENEEVK 234





>XP_005277386
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277556
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277555
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 228 KIENEEVK 235





>XP_005277554
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 381 KIENEEVK 388





>NP_001258816
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 227 KIENEEVK 234





>NP_001258799
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>NP_001258801
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIESSEVK 8
           KIE+ EVK
Sbjct: 380 KIENEEVK 387





>NP_001017520
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESSEVKS 9
           ESSEVK+
Sbjct: 233 ESSEVKA 239





>NP_004079
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESSEVKS 9
           ESSEVK+
Sbjct: 233 ESSEVKA 239





>NP_061836
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KIESSEVKS 9
            KIESSE  S
Sbjct: 1752 KIESSEEDS 1760





>NP_001264
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1617 KVEKAEVK 1624





>NP_387505
          Length = 2269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KIESSEVKS 9
            KIESSE  S
Sbjct: 1752 KIESSEEDS 1760





>XP_005261051
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KIESSEVKS 9
            KIESSE  S
Sbjct: 1674 KIESSEEDS 1682





>XP_006719025
          Length = 1902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1604 KVEKAEVK 1611





>XP_005253725
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1610 KVEKAEVK 1617





>XP_006719024
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1610 KVEKAEVK 1617





>XP_006719023
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1616 KVEKAEVK 1623





>XP_006719022
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1617 KVEKAEVK 1624





>XP_006719021
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KIESSEVK 8
            K+E +EVK
Sbjct: 1645 KVEKAEVK 1652





>NP_057382
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIESSEVKS 9
           K+E+ EVK+
Sbjct: 338 KLEAQEVKT 346





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.276   0.0993    0.201 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 268,469
Number of extensions: 348
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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