Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              20     509
XP_005273257                                                           20     509
NP_115627                                                              18    1935
XP_006718583                                                           18    1935
XP_006718582                                                           18    1935
NP_065433                                                              17    4312
NP_060500                                                              17    4312
NP_001229437                                                           17    4312
NP_542164                                                              17    4312
NP_219493                                                              17    4312
NP_001033043                                                           17    4312
XP_006722446                                                           17    4312
XP_006722445                                                           17    4312
XP_006722444                                                           17    4312
XP_006722443                                                           17    4312
XP_005277785                                                           17    4312
XP_005277784                                                           17    4312
XP_005277783                                                           17    4312
XP_005254804                                                           16    5631
XP_006720791                                                           16    5631
XP_005254803                                                           16    5631
XP_005254800                                                           16    5631
XP_005254799                                                           16    5631
XP_006712843                                                           16    5631
XP_005264079                                                           16    5631
NP_003913                                                              16    5631
NP_938080                                                              16    7355
NP_065801                                                              16    7355
NP_071396                                                              16    7355
XP_006715230                                                           16    7355
XP_006715229                                                           16    7355
XP_005249348                                                           16    7355
XP_005249347                                                           16    7355
XP_005249346                                                           16    7355
NP_001244030                                                           15    9605
NP_115749                                                              15    9605
NP_001243478                                                           15    9605
NP_001258029                                                           15    9605
NP_001129505                                                           15    9605
NP_055096                                                              15    9605
NP_510965                                                              15    9605
NP_001258028                                                           15    9605
NP_001258026                                                           15    9605
NP_001660                                                              15    9605
NP_001258025                                                           15    9605
NP_001258027                                                           15    9605
XP_005274573                                                           15    9605
XP_005274572                                                           15    9605
XP_005274571                                                           15    9605
XP_005268640                                                           15    9605
XP_006718094                                                           15    9605
XP_006718093                                                           15    9605
XP_006718092                                                           15    9605
XP_006718091                                                           15    9605
XP_006718090                                                           15    9605
XP_006714255                                                           15    9605
XP_006714253                                                           15    9605
NP_006829                                                              15    9605
>NP_064450
          Length = 1722

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            KIDQ AEEN
Sbjct: 1621 KIDQEAEEN 1629
>XP_005273257
          Length = 1726

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            KIDQ AEEN
Sbjct: 1625 KIDQEAEEN 1633
>NP_115627
          Length = 1476

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ AEEN
Sbjct: 411 QVDQLAEEN 419
>XP_006718583
          Length = 1482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ AEEN
Sbjct: 333 QVDQLAEEN 341
>XP_006718582
          Length = 1560

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ AEEN
Sbjct: 411 QVDQLAEEN 419
>NP_065433
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K DQ A+EN
Sbjct: 321 KFDQIAKEN 329
>NP_060500
          Length = 437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 372 EIDQASEE 379
>NP_001229437
          Length = 568

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 503 EIDQASEE 510
>NP_542164
          Length = 950

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 885 EIDQASEE 892
>NP_219493
          Length = 472

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ+ EEN
Sbjct: 131 RLDQSMEEN 139
>NP_001033043
          Length = 683

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ+ EEN
Sbjct: 342 RLDQSMEEN 350
>XP_006722446
          Length = 889

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 824 EIDQASEE 831
>XP_006722445
          Length = 905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 840 EIDQASEE 847
>XP_006722444
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 849 EIDQASEE 856
>XP_006722443
          Length = 925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KIDQAAEE 8
           +IDQA+EE
Sbjct: 860 EIDQASEE 867
>XP_005277785
          Length = 478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ+ EEN
Sbjct: 131 RLDQSMEEN 139
>XP_005277784
          Length = 688

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ+ EEN
Sbjct: 341 RLDQSMEEN 349
>XP_005277783
          Length = 689

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KIDQAAEEN 9
           ++DQ+ EEN
Sbjct: 342 RLDQSMEEN 350
>XP_005254804
          Length = 4796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2551 EIDQQAEES 2559
>XP_006720791
          Length = 4853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2608 EIDQQAEES 2616
>XP_005254803
          Length = 4854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2616 EIDQQAEES 2624
>XP_005254800
          Length = 4861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2616 EIDQQAEES 2624
>XP_005254799
          Length = 4861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2616 EIDQQAEES 2624
>XP_006712843
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIDQAAEE 8
           KIDQ AE+
Sbjct: 112 KIDQLAEQ 119
>XP_005264079
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KIDQAAEE 8
           KIDQ AE+
Sbjct: 107 KIDQLAEQ 114
>NP_003913
          Length = 4861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KIDQAAEEN 9
            +IDQ AEE+
Sbjct: 2616 EIDQQAEES 2624
>NP_938080
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           ++DQA  EN
Sbjct: 103 RVDQAYREN 111
>NP_065801
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DQAAEEN 9
           D+AA+EN
Sbjct: 944 DEAADEN 950
>NP_071396
          Length = 1805

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1526 KIDSEEEEN 1534
>XP_006715230
          Length = 1734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1455 KIDSEEEEN 1463
>XP_006715229
          Length = 1782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1503 KIDSEEEEN 1511
>XP_005249348
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1553 KIDSEEEEN 1561
>XP_005249347
          Length = 1837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1566 KIDSEEEEN 1574
>XP_005249346
          Length = 1845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    KIDQAAEEN 9
            KID   EEN
Sbjct: 1566 KIDSEEEEN 1574
>NP_001244030
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K+D+  +EN
Sbjct: 118 KVDEEGDEN 126
>NP_115749
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K+D+  +EN
Sbjct: 118 KVDEEGDEN 126
>NP_001243478
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K+D+  +EN
Sbjct: 118 KVDEEGDEN 126
>NP_001258029
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 155 IDQLAEE 161
>NP_001129505
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 172 IDQLAEE 178
>NP_055096
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 198 IDQLAEE 204
>NP_510965
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 215 IDQLAEE 221
>NP_001258028
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 186 IDQLAEE 192
>NP_001258026
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 169 IDQLAEE 175
>NP_001660
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  IDQAAEE 8
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>NP_001258025
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 197 IDQLAEE 203
>NP_001258027
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IDQAAEE 8
           IDQ AEE
Sbjct: 214 IDQLAEE 220
>XP_005274573
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  IDQAAEE 8
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005274572
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  IDQAAEE 8
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005274571
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  IDQAAEE 8
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005268640
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IDQAAEE 8
           +DQA+EE
Sbjct: 157 LDQASEE 163
>XP_006718094
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  KIDQAAEEN 9
          K+D+  +EN
Sbjct: 52 KVDEEGDEN 60
>XP_006718093
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  KIDQAAEEN 9
          K+D+  +EN
Sbjct: 53 KVDEEGDEN 61
>XP_006718092
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  KIDQAAEEN 9
          K+D+  +EN
Sbjct: 53 KVDEEGDEN 61
>XP_006718091
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K+D+  +EN
Sbjct: 118 KVDEEGDEN 126
>XP_006718090
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KIDQAAEEN 9
           K+D+  +EN
Sbjct: 117 KVDEEGDEN 125
>XP_006714255
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    KIDQAAEEN 9
            KID  +E+N
Sbjct: 1474 KIDMTSEKN 1482
>XP_006714253
          Length = 2069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    KIDQAAEEN 9
            KID  +E+N
Sbjct: 1486 KIDMTSEKN 1494
>NP_006829
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IDQAAEE 8
           +DQA+EE
Sbjct: 158 LDQASEE 164
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.111    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 455,366
Number of extensions: 1057
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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