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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001077059                                                           18    1135
XP_005264440                                                           18    1135
XP_006712099                                                           18    1135
XP_005264439                                                           18    1135
XP_005264438                                                           18    1135
NP_060197                                                              18    1135
NP_004110                                                              18    1482
NP_002323                                                              17    2528
NP_005831                                                              16    7355
XP_005274857                                                           16    7355
XP_005274700                                                           16    7355
XP_005274699                                                           16    7355
NP_000072                                                              15    9605
NP_065194                                                              15    9605
NP_001008                                                              15    9605
NP_001276018                                                           15    9605
NP_079048                                                              15    9605
NP_001276019                                                           15    9605
NP_001276017                                                           15    9605
NP_001276020                                                           15    9605
NP_001235                                                              15    9605
NP_078896                                                              15    9605
XP_006723447                                                           15    9605
XP_006723446                                                           15    9605
XP_006723445                                                           15    9605
XP_006723444                                                           15    9605
XP_006717388                                                           15    9605
XP_005273087                                                           15    9605
XP_006711794                                                           15    9605
XP_005273086                                                           15    9605
XP_005273085                                                           15    9605
XP_005273084                                                           15    9605
XP_005271279                                                           15    9605
XP_005271277                                                           15    9605
XP_005271276                                                           15    9605
XP_005271275                                                           15    9605
XP_005271273                                                           15    9605

>NP_001077059
          Length = 644

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KHLSQSALV 9
           KHLSQS+L+
Sbjct: 364 KHLSQSSLL 372



>XP_005264440
          Length = 352

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  KHLSQSALV 9
          KHLSQS+L+
Sbjct: 72 KHLSQSSLL 80



>XP_006712099
          Length = 708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KHLSQSALV 9
           KHLSQS+L+
Sbjct: 428 KHLSQSSLL 436



>XP_005264439
          Length = 715

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KHLSQSALV 9
           KHLSQS+L+
Sbjct: 435 KHLSQSSLL 443



>XP_005264438
          Length = 753

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KHLSQSALV 9
           KHLSQS+L+
Sbjct: 473 KHLSQSSLL 481



>NP_060197
          Length = 689

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KHLSQSALV 9
           KHLSQS+L+
Sbjct: 409 KHLSQSSLL 417



>NP_004110
          Length = 993

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KHLSQSALV 9
           KH SQSALV
Sbjct: 334 KHPSQSALV 342



>NP_002323
          Length = 4544

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    HLSQSAL 8
            HLSQSAL
Sbjct: 1305 HLSQSAL 1311



>NP_005831
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KHLSQSAL 8
          +HLSQS++
Sbjct: 77 QHLSQSSI 84



>XP_005274857
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KHLSQSAL 8
          +HLSQS++
Sbjct: 77 QHLSQSSI 84



>XP_005274700
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KHLSQSAL 8
          +HLSQS++
Sbjct: 77 QHLSQSSI 84



>XP_005274699
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KHLSQSAL 8
          +HLSQS++
Sbjct: 77 QHLSQSSI 84



>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLSQSALV 9
            HLSQS ++
Sbjct: 1145 HLSQSKVI 1152



>NP_065194
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    HLSQSAL 8
            H SQSAL
Sbjct: 1300 HTSQSAL 1306



>NP_001008
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KHLSQSAL 8
          K LSQSAL
Sbjct: 9  KGLSQSAL 16



>NP_001276018
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 783 KHISQS 788



>NP_079048
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 802 KHISQS 807



>NP_001276019
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 802 KHISQS 807



>NP_001276017
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 802 KHISQS 807



>NP_001276020
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 442 KHISQS 447



>NP_001235
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KHLSQSALV 9
           KH+ + ALV
Sbjct: 166 KHIKKQALV 174



>NP_078896
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  HLSQSAL 8
          HL QSAL
Sbjct: 46 HLRQSAL 52



>XP_006723447
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  HLSQSAL 8
          HL QSAL
Sbjct: 46 HLRQSAL 52



>XP_006723446
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  HLSQSAL 8
          HL QSAL
Sbjct: 46 HLRQSAL 52



>XP_006723445
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  HLSQSAL 8
          HL QSAL
Sbjct: 46 HLRQSAL 52



>XP_006723444
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  HLSQSAL 8
          HL QSAL
Sbjct: 46 HLRQSAL 52



>XP_006717388
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KHLSQSALV 9
           KH+ + ALV
Sbjct: 102 KHIKKQALV 110



>XP_005273087
          Length = 2788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLSQSALV 9
            HLSQS ++
Sbjct: 1145 HLSQSKVI 1152



>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLSQSALV 9
           HLSQS ++
Sbjct: 366 HLSQSKVI 373



>XP_005273086
          Length = 3264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLSQSALV 9
            HLSQS ++
Sbjct: 1145 HLSQSKVI 1152



>XP_005273085
          Length = 3755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLSQSALV 9
            HLSQS ++
Sbjct: 1145 HLSQSKVI 1152



>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLSQSALV 9
            HLSQS ++
Sbjct: 1145 HLSQSKVI 1152



>XP_005271279
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 442 KHISQS 447



>XP_005271277
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 611 KHISQS 616



>XP_005271276
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 727 KHISQS 732



>XP_005271275
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 727 KHISQS 732



>XP_005271273
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KHLSQS 6
           KH+SQS
Sbjct: 790 KHISQS 795



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.117    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 409,410
Number of extensions: 301
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)