Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              19     665
NP_653080                                                              19     665
XP_005267292                                                           19     665
XP_005267291                                                           19     665
XP_005267290                                                           19     665
NP_001367                                                              17    4312
NP_699179                                                              16    5631
XP_005253923                                                           16    5631
NP_036306                                                              16    5631
NP_899236                                                              16    7355
NP_001714                                                              16    7355
NP_056363                                                              16    7355
NP_001138241                                                           16    7355
NP_036230                                                              16    7355
NP_001138242                                                           16    7355
NP_001073940                                                           16    7355
XP_006717093                                                           16    7355
XP_006715232                                                           16    7355
XP_005249383                                                           16    7355
XP_005249382                                                           16    7355
XP_005249381                                                           16    7355
XP_005249380                                                           16    7355
XP_005249379                                                           16    7355
XP_005249377                                                           16    7355
XP_005249376                                                           16    7355
XP_005249375                                                           16    7355
XP_005249374                                                           16    7355
XP_005249373                                                           16    7355
XP_005249372                                                           16    7355
XP_005249371                                                           16    7355
XP_005249370                                                           16    7355
XP_005249369                                                           16    7355
XP_005249368                                                           16    7355
XP_005249367                                                           16    7355
XP_006711366                                                           16    7355
XP_005245198                                                           16    7355
XP_006711365                                                           16    7355
XP_006711364                                                           16    7355
NP_892021                                                              15    9605
NP_001273384                                                           15    9605
NP_068764                                                              15    9605
XP_006724469                                                           15    9605
XP_006715228                                                           15    9605
XP_005249342                                                           15    9605
XP_005270837                                                           15    9605
XP_005270836                                                           15    9605
NP_056297                                                              15    9605
>NP_005091
          Length = 1782

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGVVSEVEM 9
           +GVVSEVEM
Sbjct: 494 EGVVSEVEM 502
>NP_653080
          Length = 1684

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGVVSEVEM 9
           +GVVSEVEM
Sbjct: 396 EGVVSEVEM 404
>XP_005267292
          Length = 1677

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGVVSEVEM 9
           +GVVSEVEM
Sbjct: 389 EGVVSEVEM 397
>XP_005267291
          Length = 1684

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGVVSEVEM 9
           +GVVSEVEM
Sbjct: 396 EGVVSEVEM 404
>XP_005267290
          Length = 1782

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGVVSEVEM 9
           +GVVSEVEM
Sbjct: 494 EGVVSEVEM 502
>NP_001367
          Length = 4646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GVVSEVE 8
            G+VSEVE
Sbjct: 1042 GIVSEVE 1048
>NP_699179
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KG VSE+E
Sbjct: 199 KGAVSELE 206
>XP_005253923
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KG VSE+E
Sbjct: 199 KGAVSELE 206
>NP_036306
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KG VSE+E
Sbjct: 133 KGAVSELE 140
>NP_899236
          Length = 5497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1335 KMLVSEIEM 1343
>NP_001714
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1009 KMLVSEIEM 1017
>NP_056363
          Length = 5171

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1009 KMLVSEIEM 1017
>NP_001138241
          Length = 5675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1513 KMLVSEIEM 1521
>NP_036230
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVVSEVEM 9
           G+VSEV++
Sbjct: 115 GIVSEVKL 122
>NP_001138242
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1375 KMLVSEIEM 1383
>NP_001073940
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVVSEVEM 9
           KG++SE E+
Sbjct: 904 KGLISEEEL 912
>XP_006717093
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVVSEVEM 9
           G+VSEV++
Sbjct: 115 GIVSEVKL 122
>XP_006715232
          Length = 7498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1335 KMLVSEIEM 1343
>XP_005249383
          Length = 3186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249382
          Length = 5732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249381
          Length = 7281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1009 KMLVSEIEM 1017
>XP_005249380
          Length = 7607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1335 KMLVSEIEM 1343
>XP_005249379
          Length = 7633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1361 KMLVSEIEM 1369
>XP_005249377
          Length = 7640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1368 KMLVSEIEM 1376
>XP_005249376
          Length = 7647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1375 KMLVSEIEM 1383
>XP_005249375
          Length = 7680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1408 KMLVSEIEM 1416
>XP_005249374
          Length = 7709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249373
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1451 KMLVSEIEM 1459
>XP_005249372
          Length = 7785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1513 KMLVSEIEM 1521
>XP_005249371
          Length = 7788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249370
          Length = 7794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249369
          Length = 7797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1525 KMLVSEIEM 1533
>XP_005249368
          Length = 7812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_005249367
          Length = 7818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            K +VSE+EM
Sbjct: 1546 KMLVSEIEM 1554
>XP_006711366
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVVSEVEM 9
           KG++SE E+
Sbjct: 745 KGLISEEEL 753
>XP_005245198
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVVSEVEM 9
           KG++SE E+
Sbjct: 904 KGLISEEEL 912
>XP_006711365
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVVSEVEM 9
           KG++SE E+
Sbjct: 913 KGLISEEEL 921
>XP_006711364
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVVSEVEM 9
           KG++SE E+
Sbjct: 914 KGLISEEEL 922
>NP_892021
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GVVSEVE 8
           GVV EVE
Sbjct: 545 GVVGEVE 551
>NP_001273384
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KGV+ E+E
Sbjct: 118 KGVIPELE 125
>NP_068764
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KGV+ E+E
Sbjct: 118 KGVIPELE 125
>XP_006724469
          Length = 2373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KGVVSEVEM 9
            +GV +EVE+
Sbjct: 1930 RGVANEVEV 1938
>XP_006715228
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KGV+ E+E
Sbjct: 102 KGVIPELE 109
>XP_005249342
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KGV+ E+E
Sbjct: 399 KGVIPELE 406
>XP_005270837
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GVVSEVE 8
           GVV EVE
Sbjct: 339 GVVGEVE 345
>XP_005270836
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GVVSEVE 8
           GVV EVE
Sbjct: 339 GVVGEVE 345
>NP_056297
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVVSEVE 8
           KGV+ E+E
Sbjct: 399 KGVIPELE 406
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.123    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,509
Number of extensions: 579
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package