Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     665
NP_000242                                                              19     665
XP_005264389                                                           19     665
NP_060060                                                              18    1935
NP_116317                                                              17    2528
XP_005250956                                                           17    4312
NP_000828                                                              17    4312
NP_001009184                                                           17    4312
NP_006717                                                              16    5631
NP_001186211                                                           16    5631
NP_079148                                                              16    5631
XP_005266042                                                           16    5631
XP_005266041                                                           16    5631
XP_005263434                                                           16    5631
XP_005263433                                                           16    5631
XP_005263432                                                           16    5631
XP_005263431                                                           16    5631
XP_006714492                                                           16    5631
XP_005263430                                                           16    5631
XP_005263429                                                           16    5631
NP_851322                                                              16    7355
NP_062563                                                              16    7355
NP_620417                                                              15    9605
NP_001171582                                                           15    9605
NP_001171583                                                           15    9605
NP_689501                                                              15    9605
NP_997191                                                              15    9605
NP_001028755                                                           15    9605
NP_055793                                                              15    9605
NP_001032248                                                           15    9605
NP_001275929                                                           15    9605
NP_001275930                                                           15    9605
NP_001152956                                                           15    9605
NP_705837                                                              15    9605
NP_001272964                                                           15    9605
NP_001659                                                              15    9605
NP_001272965                                                           15    9605
NP_848514                                                              15    9605
NP_001252541                                                           15    9605
NP_057368                                                              15    9605
NP_996882                                                              15    9605
NP_001184254                                                           15    9605
NP_001129584                                                           15    9605
NP_689536                                                              15    9605
NP_996531                                                              15    9605
XP_005274529                                                           15    9605
XP_005274528                                                           15    9605
XP_005274527                                                           15    9605
XP_006724226                                                           15    9605
XP_006724225                                                           15    9605
XP_006720485                                                           15    9605
XP_006720484                                                           15    9605
XP_006720483                                                           15    9605
XP_005254088                                                           15    9605
XP_006719978                                                           15    9605
XP_005254087                                                           15    9605
XP_006719746                                                           15    9605
XP_005253685                                                           15    9605
XP_005253684                                                           15    9605
XP_005268704                                                           15    9605
XP_006719302                                                           15    9605
XP_006719301                                                           15    9605
XP_005268703                                                           15    9605
XP_005246968                                                           15    9605
XP_006711682                                                           15    9605
XP_005245214                                                           15    9605
XP_005245211                                                           15    9605
XP_005245210                                                           15    9605
XP_005245208                                                           15    9605
NP_073623                                                              15    9605
NP_003950                                                              15    9605
NP_001004684                                                           15    9605
NP_001004692                                                           15    9605
>NP_001245210
          Length = 868

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KGV TFMAE
Sbjct: 654 KGVSTFMAE 662
>NP_000242
          Length = 934

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KGV TFMAE
Sbjct: 720 KGVSTFMAE 728
>XP_005264389
          Length = 921

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KGV TFMAE
Sbjct: 720 KGVSTFMAE 728
>NP_060060
          Length = 977

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           +G+FTF+ E
Sbjct: 547 QGIFTFLCE 555
>NP_116317
          Length = 108

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KGVFTFM 7
          KGVFTF+
Sbjct: 33 KGVFTFV 39
>XP_005250956
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VFTFMAE 9
           VFTF+AE
Sbjct: 182 VFTFVAE 188
>NP_000828
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VFTFMAE 9
           VFTF+AE
Sbjct: 182 VFTFVAE 188
>NP_001009184
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VFTFMAE 9
           VFTF+AE
Sbjct: 182 VFTFVAE 188
>NP_006717
          Length = 2863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>NP_001186211
          Length = 2851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>NP_079148
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KGVF+F A
Sbjct: 271 KGVFSFEA 278
>XP_005266042
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KGVF+F A
Sbjct: 215 KGVFSFEA 222
>XP_005266041
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KGVF+F A
Sbjct: 215 KGVFSFEA 222
>XP_005263434
          Length = 1557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_005263433
          Length = 2832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_005263432
          Length = 2852

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_005263431
          Length = 2857

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_006714492
          Length = 2867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_005263430
          Length = 2868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>XP_005263429
          Length = 2868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   KGVFTFMAE 9
           KG F F AE
Sbjct: 387 KGTFKFKAE 395
>NP_851322
          Length = 724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   VFTFMA 8
           +FTFMA
Sbjct: 589 IFTFMA 594
>NP_062563
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           +G+ T+MAE
Sbjct: 157 RGIPTYMAE 165
>NP_620417
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFMA+
Sbjct: 110 FTFMAQ 115
>NP_001171582
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFMA+
Sbjct: 110 FTFMAQ 115
>NP_001171583
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFMA+
Sbjct: 110 FTFMAQ 115
>NP_689501
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   GVFTFMAE 9
           G F F+AE
Sbjct: 158 GTFLFLAE 165
>NP_997191
          Length = 1888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGVFTFMAE 9
           +GVFT + E
Sbjct: 598 QGVFTLLKE 606
>NP_001028755
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFM+E
Sbjct: 393 FTFMSE 398
>NP_055793
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTF+AE
Sbjct: 967 FTFLAE 972
>NP_001032248
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFM+E
Sbjct: 402 FTFMSE 407
>NP_001275929
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   GVFTFMAE 9
           G FTF  E
Sbjct: 523 GTFTFQCE 530
>NP_001275930
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   GVFTFMAE 9
           G FTF  E
Sbjct: 523 GTFTFQCE 530
>NP_001152956
          Length = 1736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGVFTFMAE 9
           +GVFT + E
Sbjct: 598 QGVFTLLKE 606
>NP_705837
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   GVFTFMAE 9
           G FTF  E
Sbjct: 532 GTFTFQCE 539
>NP_001272964
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 356 EGIFTFV 362
>NP_001659
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 370 EGIFTFV 376
>NP_001272965
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 370 EGIFTFV 376
>NP_848514
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 355 EGIFTFV 361
>NP_001252541
          Length = 2371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KG+ T+MA
Sbjct: 918 KGLVTYMA 925
>NP_057368
          Length = 2376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KG+ T+MA
Sbjct: 923 KGLVTYMA 930
>NP_996882
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGVFTFMA 8
           KG+ T+MA
Sbjct: 923 KGLVTYMA 930
>NP_001184254
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 355 EGIFTFV 361
>NP_001129584
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KGVFTFMAE 9
          +GVF F+ E
Sbjct: 8  EGVFIFLIE 16
>NP_689536
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KG+F F+++
Sbjct: 137 KGIFQFVSK 145
>NP_996531
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   KGVFTF 6
           KG FTF
Sbjct: 309 KGAFTF 314
>XP_005274529
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFM+E
Sbjct: 333 FTFMSE 338
>XP_005274528
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFM+E
Sbjct: 333 FTFMSE 338
>XP_005274527
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFM+E
Sbjct: 405 FTFMSE 410
>XP_006724226
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   GVFTFMAE 9
           G FTF  E
Sbjct: 523 GTFTFQCE 530
>XP_006724225
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   GVFTFMAE 9
           G FTF  E
Sbjct: 523 GTFTFQCE 530
>XP_006720485
          Length = 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FTFMAE 9
          FTFMA+
Sbjct: 39 FTFMAQ 44
>XP_006720484
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFMA+
Sbjct: 110 FTFMAQ 115
>XP_006720483
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FTFMAE 9
           FTFMA+
Sbjct: 128 FTFMAQ 133
>XP_005254088
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   KGVFTF 6
           KG FTF
Sbjct: 275 KGAFTF 280
>XP_006719978
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   KGVFTF 6
           KG FTF
Sbjct: 309 KGAFTF 314
>XP_005254087
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   KGVFTF 6
           KG FTF
Sbjct: 309 KGAFTF 314
>XP_006719746
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  KGVFTF 6
          KG FTF
Sbjct: 50 KGAFTF 55
>XP_005253685
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  KGVFTF 6
          KG FTF
Sbjct: 50 KGAFTF 55
>XP_005253684
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  KGVFTF 6
          KG FTF
Sbjct: 62 KGAFTF 67
>XP_005268704
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KG+F F+++
Sbjct: 121 KGIFQFVSK 129
>XP_006719302
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KG+F F+++
Sbjct: 137 KGIFQFVSK 145
>XP_006719301
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KG+F F+++
Sbjct: 137 KGIFQFVSK 145
>XP_005268703
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KGVFTFMAE 9
           KG+F F+++
Sbjct: 137 KGIFQFVSK 145
>XP_005246968
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGVFTFMAE 9
           +GVF F+ E
Sbjct: 229 EGVFVFLNE 237
>XP_006711682
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGVFTFMAE 9
           +GVFT + E
Sbjct: 449 QGVFTLLKE 457
>XP_005245214
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 370 EGIFTFV 376
>XP_005245211
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 361 EGIFTFV 367
>XP_005245210
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 365 EGIFTFV 371
>XP_005245208
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGVFTFM 7
           +G+FTF+
Sbjct: 370 EGIFTFV 376
>NP_073623
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   GVFTFM 7
           G+FTF+
Sbjct: 157 GIFTFL 162
>NP_003950
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  KGVFTF 6
          KG FTF
Sbjct: 62 KGAFTF 67
>NP_001004684
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   GVFTFM 7
           G+FT+M
Sbjct: 271 GIFTYM 276
>NP_001004692
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   GVFTFM 7
           G+FT+M
Sbjct: 253 GIFTYM 258
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.141    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 382,071
Number of extensions: 652
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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