Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              19     869
NP_001006619                                                           17    3301
NP_001006618                                                           17    3301
NP_001006620                                                           17    3301
NP_077022                                                              17    3301
NP_001006621                                                           17    3301
NP_001006622                                                           17    3301
NP_055965                                                              16    5631
XP_006713134                                                           16    5631
XP_006713133                                                           16    5631
XP_005265045                                                           16    5631
XP_005265044                                                           16    5631
XP_006713132                                                           16    5631
XP_005265043                                                           16    5631
XP_005265042                                                           16    5631
NP_002200                                                              16    7355
NP_003090                                                              16    7355
NP_001107852                                                           16    7355
NP_001229862                                                           16    7355
NP_683758                                                              16    7355
NP_003881                                                              16    7355
XP_006721107                                                           16    7355
XP_005255370                                                           16    7355
XP_005254668                                                           16    7355
XP_005254667                                                           16    7355
NP_056321                                                              15    9605
NP_640339                                                              15    9605
NP_001888                                                              15    9605
NP_114418                                                              15    9605
NP_001116451                                                           15    9605
NP_006258                                                              15    9605
NP_054722                                                              15    9605
NP_001640                                                              15    9605
NP_065859                                                              15    9605
NP_056502                                                              15    9605
NP_001276916                                                           15    9605
NP_001164102                                                           15    9605
XP_005276387                                                           15    9605
XP_005274557                                                           15    9605
XP_005256326                                                           15    9605
XP_006717042                                                           15    9605
XP_005251797                                                           15    9605
XP_005272420                                                           15    9605
XP_005248771                                                           15    9605
XP_005248770                                                           15    9605
XP_005264063                                                           15    9605
XP_005264062                                                           15    9605
XP_005264061                                                           15    9605
XP_005264060                                                           15    9605
XP_005264059                                                           15    9605
XP_006711862                                                           15    9605
XP_005273271                                                           15    9605
XP_005273270                                                           15    9605
XP_005273269                                                           15    9605
XP_005273268                                                           15    9605
XP_005273266                                                           15    9605
XP_006711861                                                           15    9605
XP_005273343                                                           15    9605
XP_005270781                                                           15    9605
XP_005276080                                                           15    9605
NP_690850                                                              15    9605
>NP_002430
          Length = 1137

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KGSQTISGI 9
           KGSQ ISGI
Sbjct: 484 KGSQIISGI 492
>NP_001006619
          Length = 323

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 313 KGSQKVSG 320
>NP_001006618
          Length = 522

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 313 KGSQKVSG 320
>NP_001006620
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 313 KGSQKVSG 320
>NP_077022
          Length = 486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 313 KGSQKVSG 320
>NP_001006621
          Length = 330

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 121 KGSQKVSG 128
>NP_001006622
          Length = 330

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGSQ +SG
Sbjct: 121 KGSQKVSG 128
>NP_055965
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_006713134
          Length = 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_006713133
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_005265045
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_005265044
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 276 KNGQTVSGL 284
>XP_006713132
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_005265043
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>XP_005265042
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           K  QT+SG+
Sbjct: 306 KNGQTVSGL 314
>NP_002200
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGSQTISGI 9
           +G+Q +SGI
Sbjct: 570 EGTQVLSGI 578
>NP_003090
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GSQTISG 8
           G+QT+SG
Sbjct: 275 GTQTLSG 281
>NP_001107852
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGSQTISGI 9
           +G+Q +SGI
Sbjct: 487 EGTQVLSGI 495
>NP_001229862
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GSQTISG 8
           G+QT+SG
Sbjct: 275 GTQTLSG 281
>NP_683758
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GSQTISG 8
           G+QT+SG
Sbjct: 210 GTQTLSG 216
>NP_003881
          Length = 5405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KGSQTIS 7
           +GSQT+S
Sbjct: 912 RGSQTVS 918
>XP_006721107
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGSQTISGI 9
           +G+Q +SGI
Sbjct: 487 EGTQVLSGI 495
>XP_005255370
          Length = 1169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGSQTISGI 9
           +G+Q +SGI
Sbjct: 570 EGTQVLSGI 578
>XP_005254668
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GSQTISG 8
           G+QT+SG
Sbjct: 117 GTQTLSG 123
>XP_005254667
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GSQTISG 8
           G+QT+SG
Sbjct: 177 GTQTLSG 183
>NP_056321
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GSQTISGI 9
           G+Q ISG+
Sbjct: 141 GNQRISGV 148
>NP_640339
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 462 KGSRKVSG 469
>NP_001888
          Length = 2322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGSQTIS 7
            KGSQT++
Sbjct: 1585 KGSQTLT 1591
>NP_114418
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 110 KGSRLVSG 117
>NP_001116451
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 110 KGSRLVSG 117
>NP_006258
          Length = 3224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1102 GSKNVSGI 1109
>NP_054722
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KGSQTI 6
           KGSQT+
Sbjct: 446 KGSQTV 451
>NP_001640
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KGSQTISG 8
            +GSQ +SG
Sbjct: 1134 RGSQHVSG 1141
>NP_065859
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>NP_056502
          Length = 1213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    KGSQTISG 8
            +G+Q++SG
Sbjct: 1140 RGTQSVSG 1147
>NP_001276916
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    KGSQTISG 8
            +G+Q++SG
Sbjct: 1143 RGTQSVSG 1150
>NP_001164102
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 110 KGSRLVSG 117
>XP_005276387
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KGSQTISG 8
          +G+Q+ISG
Sbjct: 73 QGNQSISG 80
>XP_005274557
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KGSQTISG 8
            +GSQ +SG
Sbjct: 1134 RGSQHVSG 1141
>XP_005256326
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KGSQTI 6
           KGSQT+
Sbjct: 411 KGSQTV 416
>XP_006717042
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 236 KGSRKVSG 243
>XP_005251797
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 421 KGSRKVSG 428
>XP_005272420
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KGSQTISG 8
          +G+Q+ISG
Sbjct: 73 QGNQSISG 80
>XP_005248771
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    KGSQTISG 8
            +G+Q++SG
Sbjct: 1140 RGTQSVSG 1147
>XP_005248770
          Length = 1213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    KGSQTISG 8
            +G+Q++SG
Sbjct: 1140 RGTQSVSG 1147
>XP_005264063
          Length = 3136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1102 GSKNVSGI 1109
>XP_005264062
          Length = 3232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1076 GSKNVSGI 1083
>XP_005264061
          Length = 3232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1102 GSKNVSGI 1109
>XP_005264060
          Length = 3250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1102 GSKNVSGI 1109
>XP_005264059
          Length = 3258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GSQTISGI 9
            GS+ +SGI
Sbjct: 1102 GSKNVSGI 1109
>XP_006711862
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273271
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273270
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273269
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273268
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273266
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_006711861
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KGSQTISGI 9
            KG+ T SGI
Sbjct: 1259 KGASTDSGI 1267
>XP_005273343
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KGSQTISG 8
           KGS+ +SG
Sbjct: 110 KGSRLVSG 117
>XP_005270781
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GSQTISGI 9
          G+Q ISG+
Sbjct: 76 GNQRISGV 83
>XP_005276080
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KGSQTISG 8
          +G+Q+ISG
Sbjct: 73 QGNQSISG 80
>NP_690850
          Length = 1714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGSQTISGI 9
           KG Q +SG+
Sbjct: 551 KGDQGLSGL 559
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.125    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 506,101
Number of extensions: 1024
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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